Saturday 17 October 2026
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Protalix BioTherapeutics, Inc.
Protalix BioTherapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $52.7 million, down 1.23% from fiscal 2024. In the quarter to June 2026, revenue grew 27.1%, EPS grew 2,281.0% and free cash flow fell 94.1%, each against the same quarter a year earlier. Insiders bought in the last twelve months.
2.62
0.08
−2.96%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 2.60 | 3.80 | 2.70 | 1.70 | 2.04 | 0.79 | 0.70 | 1.21 | 0.82 | 1.32 |
Analyst estimates 2026–2028 Powerpack |
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| High | 10.20 | 15.10 | 8.30 | 6.00 | 4.87 | 7.02 | 2.00 | 3.55 | 1.96 | 3.10 | |||||
| People | |||||||||||||||
| People | Employees | 232 | 190 | 184 | 196 | 207 | 206 | 197 | 208 | 213 | 226 | ||||
| Revenue/emp, $m | 0.04 | 0.11 | 0.19 | 0.28 | 0.30 | 0.19 | 0.24 | 0.31 | 0.25 | 0.23 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 9 | 21 | 34 | 55 | 63 | 38 | 48 | 65 | 53 | 53 | ||||
| Gross margin, % | 8.71 | 27.74 | 72.83 | 80.08 | 82.71 | 57.37 | 58.87 | 64.91 | 54.46 | 48.82 | |||||
| EBT | (29) | (83) | (26) | (18) | (7) | (28) | (14) | 9 | 4 | (6) | |||||
| EBT margin, % | (317.16) | (395.86) | (77.27) | (33.42) | (10.37) | (71.92) | (30.22) | 13.08 | 7.78 | (10.63) | |||||
| Net income | (29) | (83) | (26) | (18) | (7) | (28) | (15) | 8 | 3 | (7) | |||||
| Depreciation | 3 | 4 | 4 | 5 | 5 | 4 | 1 | 1 | 1 | 1 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.91 | 1.61 | 2.33 | 3.69 | 2.16 | 0.87 | 0.98 | 0.97 | 0.74 | 0.67 | ||||
| Earnings | (2.90) | (6.50) | (1.80) | (1.23) | (0.22) | (0.62) | (0.31) | 0.12 | 0.04 | (0.08) | |||||
| Cash flow | (3.17) | (0.76) | (0.53) | (1.30) | (0.90) | (0.23) | (0.52) | (0.02) | 0.12 | (0.15) | |||||
| Capex | (0.08) | (0.07) | (0.05) | (0.04) | (0.02) | (0.03) | (0.01) | (0.02) | (0.02) | (0.02) | |||||
| Free cash flow | (3.25) | (0.84) | (0.57) | (1.35) | (0.92) | (0.26) | (0.53) | (0.04) | 0.10 | (0.17) | |||||
| Book value | (0.98) | (2.25) | (3.59) | (4.74) | (0.93) | (0.14) | (0.22) | 0.50 | 0.60 | 0.61 | |||||
| Shares, m | 10 | 13 | 15 | 15 | 29 | 44 | 48 | 68 | 73 | 79 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 14.00 | 47.00 | 0.00 | ||||
| P/S | 4.63 | 4.29 | 1.33 | 0.89 | 1.68 | 0.96 | 1.39 | 1.88 | 2.55 | 2.68 | |||||
| P/B | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 3.66 | 3.16 | 2.93 | |||||
| EV/Sales | (0.15) | 4.06 | 1.63 | 1.50 | 1.14 | 0.67 | 1.52 | 1.50 | 2.28 | 2.48 | |||||
| EV/FCF | 0.04 | (7.80) | (6.62) | (4.09) | (2.68) | (2.18) | (2.83) | (39.90) | 16.45 | (9.58) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (32) | (10) | (8) | (19) | (26) | (10) | (25) | (1) | 9 | (12) | ||||
| Capex | (1) | (1) | (1) | (1) | (1) | (1) | (1) | (1) | (1) | (2) | |||||
| Free cash flow | (33) | (11) | (8) | (20) | (27) | (12) | (26) | (2) | 7 | (14) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 6 | 40 | 28 | (8) | (31) | 28 | 12 | 24 | 34 | 40 | ||||
| Total debt | 19 | 46 | 48 | 51 | 4 | 28 | 28 | — | — | — | |||||
| Net debt | (44) | (5) | 10 | 33 | (34) | (11) | 6 | (45) | (35) | (31) | |||||
| Shareholders’ equity | (10) | (29) | (53) | (70) | (27) | (6) | (11) | 34 | 43 | 48 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (32.72) | (108.04) | (39.68) | (34.31) | (11.51) | (38.96) | (23.06) | 11.86 | 3.71 | (8.48) | ||||
| ROIC | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 29.21 | (19.92) | |||||
| ROE | (6,411.57) | 423.40 | 64.26 | 29.67 | 13.40 | 166.79 | 179.02 | 72.50 | 7.64 | (14.44) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Protalix BioTherapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| KROS Keros Therapeutics, Inc. | $220.1M | — (loss-making) | — (loss-making) | −99.83% (below 0%: shrinking) | n/m | +32.19% (above 0%: growing) | 100.00% | 0.00% | Compare |
| PLX Protalix BioTherapeutics, Inc. | $217.5M | 10.9× | 10.2× | +27.07% (above 0%: growing) | +2,280.95% (above 0%: growing) | −94.09% (below 0%: shrinking) | 60.99% | 23.48% | |
| CAMP CAMP4 Therapeutics Corporation | $216.5M | — (loss-making) | — (loss-making) | +18.84% (above 0%: growing) | n/m | −23.90% (below 0%: shrinking) | 100.00% | (752.11%) | Compare |
| PYXS Pyxis Oncology, Inc. | $215.3M | — (loss-making) | — (loss-making) | — | n/m | −5.46% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| EVMN Evommune Inc. | $215.2M | — (loss-making) | — (loss-making) | — | n/m | +21.78% (above 0%: growing) | 100.00% | 0.00% | Compare |
| MGNX MacroGenics, Inc. | $214.7M | — (loss-making) | — (loss-making) | +377.97% (above 0%: growing) | n/m | +12.88% (above 0%: growing) | 100.00% | (42.19%) | Compare |
| ALEC Alector, Inc. | $213.3M | — (loss-making) | — (loss-making) | −57.84% (below 0%: shrinking) | n/m | +30.19% (above 0%: growing) | 100.00% | (734.73%) | Compare |
| IFRX InflaRx N.V. | $212.2M | — (loss-making) | — (loss-making) | −128.93% (below 0%: shrinking) | n/m | +69.33% (above 0%: growing) | 14,029.95% | 0.00% | Compare |
| ZNTL Zentalis Pharmaceuticals, Inc. | $212.1M | — (loss-making) | — (loss-making) | — | n/m | −9.06% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| Median of peers | $214.9M | — | — | −57.84% | — | +17.33% | 100.00% | 0.00% |
Protalix BioTherapeutics, Inc. (PLX) key facts
- Concern: Protalix BioTherapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $52.7 million, down 1.23% from fiscal 2024.
- Protalix BioTherapeutics, Inc. (PLX) is a Biotechnology company in the Healthcare sector, listed on NYSE American.
- As of October 16, 2026, PLX traded at $2.62, a market capitalization of $217.5 million.
- Return on equity was −14.4% and debt-to-equity 0.00.
- Its Piotroski F-score is 3 out of 9 and its Altman Z-score is −3.05 (distress zone) for fiscal 2025.