Protalix BioTherapeutics, Inc. (PLX) vs Pyxis Oncology, Inc. (PYXS)

Protalix BioTherapeutics, Inc. and Pyxis Oncology, Inc. are both Biotechnology companies. Protalix BioTherapeutics, Inc. and Pyxis Oncology, Inc. are of similar size ($217.5M and $215.3M). Pyxis Oncology, Inc. has negative trailing earnings, so its P/E is not meaningful; Protalix BioTherapeutics, Inc. trades at 11.4×. Protalix BioTherapeutics, Inc. has the higher net margin (23.5% vs 0.00%) and the higher return on invested capital (48.5% vs 0.00%). Across the 13 metrics below, Protalix BioTherapeutics, Inc. leads on 11 and Pyxis Oncology, Inc. on 2.

Valuation

Metric PLX PYXS Biotechnology median
P/E 11.38 n/m 8.42
P/S 2.71 n/m 10.01
P/B 3.06 10.07 2.21
Price to free cash flow 28.48 n/m 21.01
EV/EBITDA 7.93 n/m 0.61
EV/Sales 2.45 n/m 9.41
Earnings yield 8.79% (78.33%) (31.85%)
Free cash flow yield 3.51% (58.96%) (24.58%)

Profitability

Metric PLX PYXS Biotechnology median
Gross margin 69.20% 0.00% 65.16%
Operating margin 28.89% 0.00% 0.00%
Net margin 23.50% 0.00% 0.00%
Free cash flow margin 9.51% 0.00% 0.00%
Return on equity 31.23% (179.10%) (56.36%)
Return on assets 20.07% (99.62%) (48.04%)
Return on invested capital 48.48% 0.00% 0.00%

Growth

Metric PLX PYXS Biotechnology median
Revenue growth (TTM) 30.14% — 6.02%
EPS growth (last fiscal year) (300.00%) 3.03% 30.26%
Revenue growth, 5-year CAGR (3.46%) — 9.41%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric PLX PYXS Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 2.94 1.34 4.72
Net debt to EBITDA 7.68 0.82 0.96

Dividend

Metric PLX PYXS Biotechnology median
Dividend yield — — 0.08%
Payout ratio — — —

Size

Metric PLX PYXS Biotechnology median
Market cap 217.54m 215.25m 132.35m

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