Puma Biotechnology, Inc.

PBYI Healthcare Biotechnology

Puma Biotechnology, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $228.4 million, down 0.91% from fiscal 2024. In the quarter to June 2026, revenue grew 7.75%, EPS grew 33.3%, free cash flow fell 88.5% and total debt fell 79.8%, each against the same quarter a year earlier. Operating cash flow growth for three consecutive years.

9.83 0.69 −6.56%
Market cap
$543.0M
P/E
18.2×
Fwd P/E
24.2×
Dividend yield
—
F-score
8/9
Altman Z
−4.16
Beneish M
−2.06
Dividend safety
n/a

Puma Biotechnology, Inc. (PBYI) P/E ratio

Alert me on P/E ratio

As of 16 October 2026, Puma Biotechnology, Inc. (PBYI) trades at a P/E ratio of 18.2×. Over the past ten years it has ranged from 0.0× (September 2023) to 2,295× (January 2023); the current reading is higher than 92% of that period. That is above the Biotechnology industry median of 8.5× and below the Healthcare sector median of 23.0×.

P/E ratio, daily

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Annual newest first

Period P/E ratio Change
FY2025 9.4× 88.89%
FY2024 5.0× (49.23%)
FY2023 9.8× (99.50%)
FY2022 1,967× —
FY2021 0.0× —
FY2020 0.0× —
FY2019 0.0× —
FY2018 0.0× —
FY2017 0.0× —

Quarterly newest first

Period P/E ratio Change
Jun 2026 15.0× 17.52%
Mar 2026 12.8× 35.32%
Dec 2025 9.4× 33.40%
Sep 2025 7.1× 102.29%
32 more quarters

Against its own ten years

Low 0.0× High 2,295×
Ten-year median 0.0×
Current reading's percentile 74

P/E ratio against peers

What P/E ratio is

Price to Earnings Ratio shows how much investors pay for each dollar of a company’s annual profit per share.

Stock Price ÷ EPS (Basic) (TTM)

The full definition of P/E ratio →

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