Puma Biotechnology, Inc.

PBYI Healthcare Biotechnology

Puma Biotechnology, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $228.4 million, down 0.91% from fiscal 2024. In the quarter to June 2026, revenue grew 7.75%, EPS grew 33.3%, free cash flow fell 88.5% and total debt fell 79.8%, each against the same quarter a year earlier. Operating cash flow growth for three consecutive years.

9.83 0.69 −6.56%
Market cap
$543.0M
P/E
18.2×
Fwd P/E
24.2×
Dividend yield
—
F-score
8/9
Altman Z
−4.16
Beneish M
−2.06
Dividend safety
n/a
Dec '25 Dec '24 Dec '23 Dec '22 Dec '21 Dec '20 Dec '19 Dec '18 Dec '17 Dec '16
Piotroski F-Score
8 5 6 4 4 4 5 — — —
P/E ratio
9.44 5.00 9.85 1,966.67 0.00 0.00 0.00 0.00 0.00 —
P/S ratio
1.30 0.64 0.91 0.81 0.49 1.80 1.25 3.08 0.00 —
Altman Z-Score
(4.16) (6.05) (5.69) (6.36) (6.82) (6.03) (5.68) (4.04) 5.12 —
P/FCF ratio
10.18 5.64 14.88 0.00 12.00 0.00 15.78 0.00 0.00 —
Altman Z″-Score (non-manufacturers)
(14.13) (16.73) (16.14) (17.56) (18.76) (17.86) (16.66) (13.98) (30.90) —
Beneish M-Score
(2.06) (2.90) (2.45) (1.81) (3.27) (3.57) (3.91) 2.20 — —
P/Operating CF
20.64 9.51 20.42 24.02 (22.73) (72.06) 216.62 109.57 (96.71) —
P/B ratio
2.28 1.61 4.00 8.54 0.00 0.00 19.43 22.51 64.61 —
EV/Sales
1.01 0.50 0.92 0.90 0.53 1.79 1.16 3.02 0.00 —
EV/EBITDA
4.80 2.69 4.92 6.13 10.58 0.00 0.00 0.00 0.00 —
EV/FCF
7.91 4.35 15.14 (8.88) 12.94 (41.98) 14.71 (30.69) (19.73) —
Current Ratio
2.00 1.54 1.57 1.73 1.28 1.28 1.83 3.02 1.82 6.31
Net Debt/EBITDA
(1.60) (0.80) 0.08 0.64 0.77 0.19 0.74 0.16 0.11 0.83
Debt/Equity
0.17 0.73 1.86 4.74 (41.16) (16.52) 5.59 4.43 0.91 0.00
ROE
27.97% 41.60% 57.54% 0.02% 693.73% (1,042.29%) (292.05%) (259.28%) (221.91%) (132.75%)
ROA
14.48% 13.64% 9.54% 0.00% (12.37%) (25.04%) (30.60%) (53.49%) (139.59%) (112.06%)
ROIC
43.78% 33.25% 35.69% 34.49% 11.10% 0.00% 0.00% (284.82%) (910.03%) 0.00%
Return on Tangible Assets
38.12% 58.16% 37.45% 0.00% (90.48%) (174.58%) (95.98%) (81.21%) (555.85%) (135.19%)
Average Days of Receivables
85.75 50.70 74.10 64.59 46.90 41.42 38.74 30.21 127.49 —
Earnings Yield
10.59% 20.00% 10.15% 0.05% (23.36%) (14.72%) (22.40%) (14.69%) (8.47%) —
Free Cash Flow Yield
9.82% 17.74% 6.72% (12.56%) 8.34% (2.36%) 6.34% (3.20%) (5.02%) —
Free Cash Flow per Share
0.83 0.80 0.30 (0.51) 0.51 (0.23) 0.57 (0.65) (6.00) (4.47)
Book value per Share
2.61 1.89 1.13 0.48 (0.06) (0.15) 0.45 0.90 1.43 6.30
Free Cash Flow
41.73 38.86 14.37 (22.83) 20.65 (9.27) 22.07 (24.71) (222.90) (148.97)
EV/EBIT
6.20 3.70 6.66 8.68 103.30 0.00 0.00 0.00 0.00 —
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