Orchestra BioMed Holdings, Inc.
OBIO Healthcare Biotechnology
Orchestra BioMed Holdings, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $33.5 million, up 1,169.2% from fiscal 2024. In the quarter to June 2026, revenue fell 89.5%, EPS grew 24.0%, free cash flow fell 25.9% and total debt rose 142.2%, each against the same quarter a year earlier. Insiders bought in the last twelve months.
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Orchestra BioMed Holdings, Inc. (OBIO) EV/Sales
As of 16 October 2026, Orchestra BioMed Holdings, Inc. (OBIO) trades at a EV/Sales of 8.5×. Over the past ten years it has ranged from 0.0× (December 2022) to 129× (April 2023); the current reading is higher than 49% of that period. That is below the Biotechnology industry median of 9.2× and above the Healthcare sector median of 3.4×.
EV/Sales, daily
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Annual newest first
| Period | EV/Sales | Change |
|---|---|---|
| FY2025 | 3.2× | (91.19%) |
| FY2024 | 35.9× | (51.69%) |
| FY2023 | 74.4× | 244.80% |
| FY2022 | 21.6× | — |
Quarterly newest first
| Period | EV/Sales | Change |
|---|---|---|
| Jun 2026 | 6.3× | 10.05% |
| Mar 2026 | 5.7× | 80.18% |
| Dec 2025 | 3.2× | (81.36%) |
| Sep 2025 | 17.0× | (40.08%) |
| 14 more quarters | Free account |
Against its own ten years
EV/Sales against peers
| Company | EV/Sales |
|---|---|
| TTRX Turn Therapeutics Inc. compare | n/m |
| RLMD Relmada Therapeutics, Inc. compare | n/m |
| AVIR Atea Pharmaceuticals, Inc. compare | 0.4× |
| ENTA Enanta Pharmaceuticals, Inc. compare | 2.0× |
| CCCC C4 Therapeutics, Inc. compare | 3.6× |
| FENC Adherex Technologies Inc. compare | 5.4× |
| OBIO Orchestra BioMed Holdings, Inc. | 8.5× |
| IRD Opus Genetics, Inc. compare | 31.5× |
| CYPH Cypherpunk Technologies Inc. compare | 311× |
| Biotechnology industry median | 9.2× |
| Healthcare sector median | 3.4× |
| Market median | 2.1× |
What EV/Sales is
EV/Sales tells an investor how the value of a whole company, counting its debt and cash, compares with the sales it brings in.
((Stock Price × Shares (Basic, Weighted) (latest quarter)) + (Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter)) − Cash & Short Term Investments (latest quarter)) ÷ Revenue (TTM)