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Entera Bio Ltd. ENTX

Insider Buys alert about insiders buying in the last 12 month

We limit data available in the Overview Report for users who do not have Powerpack

Get access to target analyst prices, predictions, compound annual growth rates and more than four years of historical data.

Insider Decisions

Total buys
0.14
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy 1 5 2
Sell
Insider Ownership
0.00%

Capital & Financial Ratios

Market Cap
526.72
Revenue
0.22
Net Income
(17.03)
Free Cash Flow
(10.99)
Net Debt
(18.43)
Current Ratio
8.98
Debt/Equity
0.00
P/E ratio
0.00
P/S ratio
669.66
P/B ratio
20.55
Past 5Y EPS Growth
22.19%
This Y EPS Growth
(36.00%)
Next Y EPS Growth
(67.65%)
Next 5Y EPS Growth
in millions of $

Dividends

Payout Ratio
0.00
Annual Dividend Rate
Annual Dividend Yield
total individual payouts
2023 ‡‡‡
2022 ‡‡‡
2021 ‡‡‡
2020 ‡‡‡
2019 ‡‡‡
2017 ‡‡‡
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 11.02 8.66 14.88 18.43
Receivables 0.13
Inventory
Other 0.24 0.19 0.42 0.47
11.26 8.97 15.30 18.90
2023 2024 2025 Q'26
Payables 0.08 0.13 0.45 0.58
ST’ Debt
Other
1.09 1.18 2.20 2.10
in millions of $

Compound Annual Growth

10y 5y 3y
Sales ‡‡‡‡‡ ‡‡‡‡‡
Cash Flow ‡‡‡ ‡‡‡
Earnings ‡‡‡ ‡‡‡
Book Value ‡‡‡‡‡ ‡‡‡‡‡

Revenue

Mar Jun Sep Dec Year
’26
’25 0.04
0.04
’24 0.06 0.04 0.08
0.18
’22 0.07 0.04 0.01 0.01
0.13
’21 0.16 0.11 0.14 0.17
0.57
’20 0.04 0.05 0.05 0.22
0.37
’19 0.07 0.06 0.10
0.24
in millions of $

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (3.09) (3.46)
’25 (1.40) (1.63) (2.50) (1.83)
(7.37)
’24 (1.86) (1.33) (2.15) (1.47)
(6.82)
’23 (1.61) (1.56) (1.52) (2.62)
(7.31)
’22 (4.79) (2.83) (2.87) (2.01)
(12.50)
’21 (2.32) (2.12) (2.11) (2.51)
(9.06)
’20 (2.66) (3.53) (2.85) (1.53)
(10.56)
in millions of $

Free Cash Flow

Mar Jun Sep Dec Year
’26 (3.09) (3.47)
’25 (1.41) (1.66) (2.54) (1.86)
(7.48)
’24 (1.86) (1.33) (2.15) (1.47)
(6.82)
’23 (1.62) (1.56) (1.52) (2.62)
(7.33)
’22 (4.81) (2.85) (2.87) (2.01)
(12.55)
’21 (2.32) (2.12) (2.12) (2.52)
(9.08)
’20 (2.68) (3.53) (2.87) (1.53)
(10.61)
in millions of $

EPS

Mar Jun Sep Dec Year
’26 (0.07) (0.14)
’25 (0.06) (0.06) (0.07) (0.07)
(0.25)
’24 (0.05) (0.06) (0.08) (0.06)
(0.25)
’23 (0.08) (0.08) (0.08) (0.07)
(0.31)
’22 (0.13) (0.11) (0.11) (0.10)
(0.45)
’21 (0.43) (0.19) (0.05) 0.21
(0.47)
’20 (0.16) (0.17) (0.09) (0.11)
(0.55)

Target Price Range

High
‡‡‡‡‡
‡‡‡
Average
‡‡‡‡‡
‡‡‡
Low
‡‡‡‡‡
‡‡‡

Recommendation Rating

1
1
Buy
2
3
Hold
4
5
Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
‡‡‡‡ ‡‡‡‡ ‡‡‡ ‡‡‡‡ 0.47 0.52 0.58 1.50
Low Price
‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡‡‡ 3.51 1.48 3.35 3.22
High Price
‡‡‡‡ ‡‡‡‡ ‡‡‡‡ ‡‡‡‡ ‡‡‡‡ 20 19 20 22
Employees
‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 0.01 0.00 0.01 0.00
Revenue/Emp
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 0.13 0.18 0.04 ‡‡‡‡‡
Revenue
‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 24.63% 4.97% 0.00%
Gross Margin
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (12.93) (8.86) (9.53) (11.44)
EBT
‡‡‡ ‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (9,652.24%) 0.00% (5,263.54%) (27,235.71%) ‡‡‡ ‡‡‡ ‡‡‡
EBT Margin
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (13.07) (8.89) (9.54) (11.44) ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Net Income
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 0.06 0.06 0.05 0.03
Depreciation
‡‡‡ ‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 0.00 0.00 0.00 0.00 ‡‡‡ ‡‡‡ ‡‡‡
Revenue/Sh
‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (0.45) (0.31) (0.25) (0.25) ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡
Earnings/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (0.43) (0.25) (0.18) (0.16)
Cash Flow/Sh
‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 0.00 0.00 0.00 0.00 ‡‡‡ ‡‡‡ ‡‡‡
Capex/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (0.44) (0.25) (0.18) (0.16)
Free CF/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 0.41 0.36 0.21 0.28
Book Value/Sh
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 28.81 29.01 37.65 46.19 ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡
Shares
‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡ 0.00 0.00 0.00 ‡‡‡‡‡ ‡‡‡‡‡
PE Ratio
‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 219.28 409.32 401.84 ‡‡‡ ‡‡‡ ‡‡‡
PS Ratio
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 2.50 9.88 6.84 ‡‡‡ ‡‡‡ ‡‡‡
PB Ratio
‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 128.13 366.97 336.90 ‡‡‡‡‡
EV/Sales
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (1.37) (10.48) (10.05)
EV/FCF
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (12.50) (7.31) (6.82) (7.37) ‡‡‡ ‡‡‡ ‡‡‡
Op' Cash Flow
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (0.05) (0.02) 0.00 (0.11)
Capex
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (12.55) (7.33) (6.82) (7.48)
FCF
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 11.51 10.17 7.80 13.10
Working Cap'
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 0.09
Total Debt
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (12.22) (11.02) (8.66) (14.88)
Net Debt
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ 11.75 10.39 8.08 13.10
Sh' Equity
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (66.84%) (71.42%) (90.20%) (90.13%)
ROA
‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡ ‡‡‡ 0.00% 0.00% 0.00% 0.00%
ROIC
‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ ‡‡‡‡‡ (76.17%) (80.30%) (103.34%) (108.01%)
ROE
predictions in italic, sparklines do not include predictions

Analyst Commentary (Summary)

Entera Bio Ltd. (ENTX), leveraging its proprietary Peptelligence platform for oral peptide delivery, is at a pivotal juncture in the burgeoning markets for osteoporosis, hypoparathyroidism, and GLP-1 therapies amid the obesity epidemic. Despite the hallmark volatility of clinical-stage biotechs—lumpy milestone revenues, escalating R&D losses projected to widen to -$34 million by 2026, and share dilution—the company’s disciplined operations shine through stable headcount, shrinking cash burn, and a cash-rich balance sheet. Recent revenue rebounds and gross margins hinting at scalable manufacturing potential echo historical biotech transitions from development to commercialization, much like peers riding oral semaglutide’s blockbuster wave.

Stock resilience stands out: trading at multi-year lows versus 2021 peaks, yet up 52% from 2022 troughs amid stabilizing fundamentals, with premiums in PS and EV/Sales multiples justified by pipeline promise. Insider confidence bolsters the case—CEO and directors scooped up over 95,000 shares at sub-$2 levels in late 2025-early 2026, with zero sells—signaling alignment ahead of key milestones.

Analyst unanimity points to ~570% upside, driven by Phase 3 topline data for EB613 (oral PTH for osteoporosis) in Q2 2026, potential partnerships tapping $1B+ markets, and GLP-1 expansion opportunities. In a sector prone to binary outcomes, Entera’s setup offers calculated asymmetry for patient investors, reminiscent of early disruptors in endocrine therapies—warranting a deeper dive into the catalysts ahead.

Entera Bio Ltd. (ENTX) Latest News

News by impact score

Fine-tune

18 Aug

4 , 8:00 AM
Entera Bio Ltd. appoints Riccardo Paolo Camisasca, M.D., as Chief Medical Officer ahead of EB613 Phase 3 initiation. CMO appointment strengthens leadership for pivotal EB613 phase 3 execution.

13 Aug

4 www.marketbeat.com, 2:04 PM
Entera Bio reaches FDA agreement to begin Phase 3 trials for oral osteoporosis drug EB613. FDA agreement to start Phase 3 for lead asset EB613 represents major regulatory progress that can shift company trajectory.

7 Aug

3 , 4:05 PM
Entera Bio Ltd. (ENTX) announced second quarter 2026 financial results and business updates. Quarterly financial results and updates provide performance indicators that can moderately affect valuation and sentiment.

4 Aug

3 , 8:30 AM
Entera Bio Phase 2 data supporting EB613 oral PTH(1-34) anabolic effect on postmenopausal women with osteoporosis at high fracture risk selected for plenary poster at ASBMR 2026 annual meeting. Phase 2 data selection for major conference plenary raises EB613 visibility and supports future development trajectory.

27 Jul

4 , 8:30 AM
Entera Bio Ltd. priced an oversubscribed $275 million private placement. Oversubscribed $275 million private placement supplies major capital to advance operations and reshape company trajectory.

22 Jun

4 GlobeNewswire, 8:30 AM
Entera Bio received positive FDA feedback on its 12-month registrational Phase 3 study for EB613, the first oral anabolic tablet in development for postmenopausal women with osteoporosis. Positive FDA feedback advances EB613 Phase 3 trial toward potential approval and commercialization.

3 stocktwits.com, 2:29 PM
ENTX stock surges toward best day in over five years amid rally driven by unspecified positive factors. Rally boosts short-term sentiment and trading but lacks details on fundamental or lasting operational changes.

16 Jun

3 , 8:33 AM
Entera Bio Ltd. presented robust preclinical data for EB612 oral treatment of hypoparathyroidism and EB618 oral GLP-1/glucagon candidate for obesity at ENDO 2026. Preclinical data advances pipeline candidates and may support further development but lacks immediate commercial or regulatory effects.

15 Jun

4 , 8:45 AM
Entera Bio will present comparative clinical data on its oral EB613 tablet, the first-in-class PTH(1-34) anabolic for osteoporosis, during an oral session at ENDO 2026. Highlighting comparative clinical data for lead candidate EB613 at ENDO 2026 can drive regulatory progress and investor attention for Entera.

28 May

3 GlobeNewswire, 8:50 AM
Entera Bio's EB613 single-tablet data for osteoporosis selected for late-breaking oral presentation at ENDO 2026; additional oral peptide pipeline data accepted for presentation. Conference presentation slot raises visibility for EB613 but remains a non-commercial milestone with limited near-term financial effect.

8 May

4 GlobeNewswire, 4:05 PM
Entera Bio Ltd. (ENTX) announced first quarter 2026 financial results and provided updates across its oral peptide programs. Quarterly financial results combined with oral peptide program updates represent major pipeline progress impacting future performance and investor sentiment.

29 Apr

3 Zacks, 12:00 PM
Entera Bio Ltd. (ENTX) upgraded to Buy rating by analysts, highlighting strong clinical pipeline progress, upcoming Phase 3 data readouts, and undervalued growth potential. Analyst upgrade to Buy reflects improved sentiment on pipeline milestones, likely driving moderate short-term stock gains and visibility.

24 Apr

4 www.marketbeat.com, 7:33 PM
Entera Bio promotes EB613, an oral anabolic tablet targeting persistent osteoporosis treatment gaps, as Phase III trials approach. EB613 nearing Phase III offers significant potential to disrupt osteoporosis market and boost Entera Bio's trajectory.

20 Apr

3 , 11:59 AM
BriefCast published the transcript of Entera Bio's Key Opinion Leader roundtable on EB613, an oral anabolic tablet opportunity for osteoporosis. KOL roundtable transcript on EB613 promotes Entera Bio's oral osteoporosis treatment potential, moderately boosting investor sentiment and pipeline visibility.

2 Apr

4 GlobeNewswire, 8:45 AM
Entera Bio Ltd. (ENTX) priced a $10.0 million direct investment from BVF Partners, with potential for up to $24.5 million in total proceeds. The $10-24.5 million funding infusion represents a major strategic financial boost for Entera Bio's operations and investor sentiment.

27 Mar

3 GlobeNewswire, 4:05 PM
Entera Bio Ltd. (ENTX) announced full year 2025 financial results and provided business updates. Full-year financial results directly affect key financial performance metrics and investor sentiment.

4 Mar

4 GlobeNewswire, 8:30 AM
Entera Bio Ltd. (ENTX) submitted a streamlined Phase 3 protocol to initiate the registrational program for EB613, an oral anabolic osteoanabolic therapy for postmenopausal women with osteoporosis. Advancing to Phase 3 registrational trial for EB613 positions ENTX for potential FDA approval and commercialization in osteoporosis market.

11 Feb

3 GlobeNewswire, 9:00 AM
Entera Bio Ltd. (ENTX) announced that members of its board have made open market purchases of the company's stock. This move is seen as a sign of confidence in the company's future prospects and aims to align the interests of the board with those of shareholders. The purchases were made at varying prices, reflecting the board members' commitment to the company's growth and stability. Board members purchasing stock indicates confidence in the company's future, which may positively influence market sentiment.

9 Feb

4 GlobeNewswire, 8:50 AM
Entera Bio Ltd. has appointed Geno J. Germano, a former Pfizer executive, as the new Chairman of the Board. This strategic move comes as the company prepares for key milestones in its development pipeline, aiming to enhance its leadership and direction in the biopharmaceutical sector. The appointment of a seasoned executive like Germano is likely to significantly impact Entera Bio's strategic direction and investor confidence.

6 Feb

4 Insider Monkey, 11:02 AM
Opko Health has expanded its partnership with Entera Bio Ltd. for the co-development of drug candidates. This collaboration aims to leverage Entera's proprietary oral drug delivery technology to enhance the bioavailability of certain therapeutic agents. The agreement is expected to accelerate the development process and potentially lead to new treatment options in the market. The expanded partnership could significantly enhance Entera's product pipeline and market positioning through innovative drug delivery solutions.

4 Feb

4 GlobeNewswire, 8:00 AM
OPKO Health and Entera Bio Ltd. have expanded their partnership to develop a first-in-class oral long-acting PTH tablet aimed at treating patients with hypoparathyroidism. This collaboration is expected to enhance the development and commercialization of the innovative treatment, which could significantly improve patient outcomes in managing this rare condition. The partnership expansion is a significant strategic move that could lead to a major product launch and positively impact Entera Bio's market position.

4 , 8:00 AM
OPKO Health and Entera Bio Ltd. (ENTX) expand partnership to advance first-in-class oral long-acting PTH tablet for hypoparathyroidism patients. Partnership expansion with OPKO accelerates Entera Bio's lead oral PTH candidate for hypoparathyroidism, enhancing pipeline value and market potential.

21 Jan

4 GlobeNewswire, 8:30 AM
Entera Bio Ltd. (ENTX) has outlined its corporate priorities and pipeline outlook for Q1 2026, focusing on advancing its therapeutic candidates and enhancing its operational strategies. The company aims to strengthen its position in the biopharmaceutical sector through strategic initiatives and potential collaborations, emphasizing innovation in its product development pipeline. Significant strategic moves and potential collaborations could alter the company's trajectory and investor sentiment.

31 Dec

3 Simply Wall St., 7:51 AM
Entera Bio Ltd. is experiencing a cash burn situation, but analysts express confidence in the company's financial management and strategic direction. The firm has sufficient cash reserves to sustain operations for the foreseeable future, allowing it to focus on its product development pipeline. Investors are reassured by the company's plans to enhance its market position and potential revenue streams, mitigating concerns over cash flow. The company's cash burn situation is manageable, but ongoing product development and market strategies will influence its financial performance.

23 Dec

4 GlobeNewswire, 8:30 AM
Entera Bio Ltd. congratulates the FNIH-ASBMR-SABRE team on the FDA's qualification of Total Hip Bone Mineral Density (BMD) as a regulatory endpoint, marking a significant advancement in osteoporosis innovation. This qualification is expected to enhance the development and approval processes for osteoporosis treatments, potentially benefiting companies involved in this field. The FDA's qualification of Total Hip BMD as a regulatory endpoint is likely to significantly impact the development of osteoporosis treatments and Entera Bio's strategic positioning in this market.

22 Dec

4 , 8:30 AM
Entera Bio Ltd. announced new data supporting the development of its first-in-class oral, long-acting PTH tablet, aimed at treating patients with hypoparathyroidism. The EB612 program shows promise in addressing unmet medical needs in this patient population, potentially improving treatment adherence and outcomes. The development of a novel treatment for hypoparathyroidism could significantly enhance Entera Bio's product portfolio and market position.

14 Nov

3 GlobeNewswire, 4:05 PM
Entera Bio Ltd. (ENTX) reported its financial results for the third quarter of 2025, highlighting key business updates and developments. The company continues to focus on advancing its pipeline and strategic initiatives aimed at enhancing shareholder value. Financial metrics indicate progress, with notable advancements in product development and partnerships. Entera Bio remains committed to its long-term goals despite market challenges. Financial results and business updates indicate moderate progress in product development and strategic initiatives.

23 Oct

4 GlobeNewswire, 8:50 AM
Entera Bio Ltd. announced positive results from its Phase 2 trial of EB613, showing significant improvements in bone density among early postmenopausal women. The trial results suggest that EB613 may be an effective treatment for osteoporosis, potentially addressing a critical need in women's health. The data indicates a favorable safety profile and supports further development of the drug. The positive clinical data from the Phase 2 trial could significantly enhance Entera Bio's market position and investor sentiment regarding its osteoporosis treatment.

16 Oct

4 GlobeNewswire, 8:45 AM
Entera Bio Ltd. (ENTX) will present new clinical data from its Phase 2 trial of EB613 at the 2025 North American Menopause Society (NAMS) Annual Meeting. This presentation is expected to provide insights into the efficacy and safety of EB613, a treatment aimed at addressing bone health in postmenopausal women. The data could influence future development strategies and market positioning for Entera Bio. The presentation of new clinical data has the potential to significantly impact Entera Bio's product development and market perception.

11 Oct

3 Simply Wall St.Simply Wall St.Simply Wall St., 8:33 AM
Entera Bio Ltd. (NASDAQ: ENTX) saw its market capitalization increase by US$34 million last week, primarily benefiting individual investors who hold significant stakes in the company. This rise in market value reflects positive sentiment and potential growth prospects for Entera Bio, attracting attention from the investment community. The increase in market cap indicates a moderately noticeable influence on investor sentiment and potential future performance.

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