Orchestra BioMed Holdings, Inc.

OBIO Healthcare Biotechnology

Orchestra BioMed Holdings, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $33.5 million, up 1,169.2% from fiscal 2024. In the quarter to June 2026, revenue fell 89.5%, EPS grew 24.0%, free cash flow fell 25.9% and total debt rose 142.2%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

5.45 0.29 −5.05%
Market cap
$345.0M
P/E
0.0×
Fwd P/E
−2.6×
Dividend yield
—
F-score
6/9
Altman Z
−2.72
Beneish M
7.00
Dividend safety
n/a
Dec '25 Dec '24 Dec '23 Dec '22 Dec '21 Dec '20 Dec '19 Dec '17
Piotroski F-Score
6 2 — — — — — —
P/E ratio
0.00 0.00 0.00 0.00 — — — —
Altman Z-Score
(2.72) (5.57) 2.27 (1.10) — — — —
P/S ratio
5.92 55.83 105.69 42.60 — — — —
P/FCF ratio
0.00 0.00 0.00 0.00 — — — —
Altman Z″-Score (non-manufacturers)
(7.20) (13.57) (4.16) (3.29) — — — —
Beneish M-Score
7.00 (3.80) (2.68) — — — — —
P/Operating CF
(87.29) (10.88) (26.58) (17.21) — — — —
P/B ratio
3.70 4.47 4.29 2.86 — — — —
EV/Sales
3.16 35.92 74.36 21.57 — — — —
EV/EBITDA
0.00 0.00 0.00 0.00 — — — —
EV/FCF
(2.14) (1.86) (4.44) (2.55) — — — —
Current Ratio
6.45 4.27 7.95 4.56 10.88 18.06 — —
Net Debt/EBITDA
1.80 0.82 1.71 2.30 4.44 11.26 — —
Debt/Equity
0.27 0.43 0.00 0.18 0.00 0.00 — —
ROE
(122.40%) (120.84%) (81.47%) (138.33%) 10.09% 4.62% — —
ROA
(55.44%) (71.21%) (51.49%) (26.11%) (0.23%) (0.21%) 0.00% —
ROIC
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% — —
Return on Tangible Assets
(57.01%) (112.28%) (62.03%) (49.71%) (23.16%) (8.55%) — —
Average Days of Receivables
1.04 12.73 13.09 9.92 — — — —
Earnings Yield
(27.23%) (41.75%) (17.08%) (22.33%) — — — —
Free Cash Flow Yield
(24.96%) (34.52%) (15.84%) (19.86%) — — — —
Free Cash Flow per Share
(1.04) (1.38) (1.39) (1.99) (0.01) (0.02) — —
Book value per Share
1.12 0.90 2.05 3.50 (0.19) (0.23) — —
Free Cash Flow
(49.45) (50.85) (46.20) (29.88) (0.27) (0.26) — —
EV/EBIT
0.00 0.00 0.00 0.00 — — — —
Other line items

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Columns are period end dates