Krystal Biotech, Inc.

KRYS Healthcare Biotechnology

Krystal Biotech, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $389.1 million, up 33.9% from fiscal 2024.

Revenue
+30.2%
EPS
−22.3%
Free cash flow
+137.8%

Quarter to September 2026, against a year earlier

300.31 0.06 +0.02%
Market cap
$8.9B
P/E
39.2×
Fwd P/E
45.7×
Dividend yield
—
F-score
7/9
Altman Z
39.03
Beneish M
−2.27
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
Piotroski F-Score
— — — — — — — — — 7
P/E ratio
— — — — — — — 694.22 50.54 34.82
P/S ratio
— — — — — — — 0.00 15.42 18.34
Altman Z-Score
— — — — — — — 50.87 25.52 39.03
P/FCF ratio
— — — — — — — 0.00 37.58 37.69
Altman Z″-Score (non-manufacturers)
— — — — — — — 23.06 12.92 16.61
Beneish M-Score
— — — — — — — — 1.05 (2.27)
P/Operating CF
— — — — — — — (469.19) 84.76 92.07
P/B ratio
— — — — — — — 4.36 4.73 5.85
EV/Sales
— — — — — — — 0.00 13.36 16.21
EV/EBITDA
— — — — — — — 0.00 53.57 37.58
EV/FCF
— — — — — — — (4,744.59) 32.57 33.31
Current Ratio
50.44 77.99 43.39 58.88 17.80 17.18 13.30 17.76 7.28 9.95
Net Debt/EBITDA
0.07 10.44 9.49 9.23 8.71 6.69 2.67 5.13 (8.25) (4.93)
Debt/Equity
6.38 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ROE
(4.76%) (32.76%) (13.39%) (12.08%) (13.00%) (15.71%) (25.09%) 1.68% 10.34% 18.91%
ROA
(4.40%) (30.29%) (13.10%) (11.74%) (12.38%) (14.85%) (23.63%) 1.59% 9.51% 17.14%
ROIC
(341.81%) 0.00% (508.36%) (149.54%) (99.05%) (27.45%) (63.43%) (27.80%) 11.78% 25.73%
Return on Tangible Assets
(53.76%) (16.01%) (9.63%) (9.50%) (11.07%) (13.15%) (27.09%) 1.53% 11.21% 19.10%
Average Days of Receivables
— — — — — — — 302.66 131.60 119.52
Earnings Yield
— — — — — — — 0.14% 1.98% 2.87%
Free Cash Flow Yield
— — — — — — — (0.02%) 2.66% 2.65%
Free Cash Flow per Share
(1.51) (0.76) (1.04) (1.58) (2.18) (5.24) (6.02) (0.02) 4.17 6.54
Book value per Share
0.33 9.23 10.11 12.76 15.55 26.74 20.49 28.68 33.10 42.14
Free Cash Flow
(1.33) (4.10) (11.68) (25.09) (40.93) (116.27) (153.55) (0.60) 119.18 189.35
EV/EBIT
— — — — — — — 0.00 59.04 39.11
Other line items

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Columns are period end dates · fundamentals updated 5 Nov 2026