Fractyl Health, Inc.

GUTS Healthcare Biotechnology

Fractyl Health, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $93,000.00, down 22.5% from fiscal 2023.

Revenue
−57.1%
EPS
+71.9%
Free cash flow
+25.3%
Total debt
+1.54%

Quarter to June 2026, against a year earlier

0.94 0.04 +4.44%
Market cap
$11.9M
P/E
0.0×
Fwd P/E
−0.3×
Dividend yield
—
F-score
n/a
Altman Z
−6.98
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Bought, $m 0.19
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy 1 — — — — — 5 — — 1 — —
Sell — — — — — — — — — — — —
Insider Ownership 14.72%

Capital & Financial Ratios $m

Size
Market Cap 11.88
Revenue ttm 0.09
Net income ttm (105.65)
Free cash flow ttm (82.43)
Net debt Q (16.69)
Valuation
P/E 0.00
Forward P/E (0.25) (negative: loss-making)
Price / sales 127.89 (above 10: high)
Forward P/S Powerpack
Price / FCF 0.00
Price / book 0.00
Financial health
Current ratio Q 3.15 (at or above 1.5: strong)
Debt / equity Q (18.29) (negative: negative equity)
Interest coverage Q —
Growth
Revenue growth Q −57.14% (below 0%: shrinking)
Operating income growth Q +26.78% (above 0%: growing)
EPS, this year +81.17% (at or above 15%: strong)
EPS, next year A −37.72% (below 0%: weak)
Revenue, next year A +31,910.75% (at or above 10%: strong)
EPS, past 5 yrs —
EPS, next 5 yrs A +42.51% (at or above 15%: strong)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 34 67 82 47
Receivables 0 — — —
Inventory 0 0 — —
Other — — — —
36 72 88 50
2023 2024 2025 Q'26
Payables 1 3 2 1
ST’ Debt — — — —
Other 1 — — —
11 20 18 16

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — — 0.00%
Earnings — — 0.00%
Book Value — — 0.00%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 0.72 (1.92) — — —
’25 (5.88) (6.84) (8.52) (0.84) (22.33)
’24 (2.04) (4.32) (5.76) (6.24) (19.45)
’23 (69.70) (174.74) (90.45) (134.21) (543.70)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 — — — — —
’24 0 0 0 0 0
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (22) (16) — — —
’25 (25) (21) (23) (21) (90)
’24 (12) (19) (18) (17) (66)
’23 (10) (12) (11) (11) (43)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (22) (16) — — —
’25 (26) (21) (23) (21) (91)
’24 (13) (19) (18) (17) (67)
’23 (10) (12) (11) (11) (43)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Jun ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — — — — 0 0 — 0 (22.5%) 1 1 28 +361.2%
Gross margin, % — — — — — — — 35.83 46.24 — 46.24 +10.4 pt
EBT — — — — — — (46) (77) (69) (141) (106) +44.8%
EBT margin, % — — — — — — 0.00 (64,242.50) (73,864.52) 0.00 0.00 0.0 pt
Net income — — — — — — (46) (77) (69) (141) (106) +44.8%
Per share, $
Per share, $ Revenue — — — — — — 0.00 0.69 0.03 0.00 0.00 n/m
Earnings — — — — — — (280.23) (543.70) (19.45) (22.33) (10.56) (57.0%)
Cash flow — — — — — — (278.91) (247.10) (18.06) (14.30) (6.24) (62.8%)
Capex — — — — — — (0.34) (2.07) (0.49) (0.09) 0.00 (36.1%)
Free cash flow — — — — — — (279.25) (249.17) (18.55) (14.39) (6.24) (62.8%)
Book value — — — — — — (1,521.83) (1,875.72) 7.84 1.50 (0.13) n/m
Shares, m — — — — — — 0 0 4 6 10 +236.5%
Valuation, ×
Valuation, × P/E — — — — — — — 0.00 0.00 — 0.00 0.0
P/S — — — — — — — 225.02 964.08 — 127.89 594.5
P/B — — — — — — — 0.00 3.15 — 0.00 1.6
EV/Sales — — — — — — — 405.25 562.98 — (51.61) 484.1
EV/FCF — — — — — — — (1.13) (0.78) — 0.06 (1.0)
Cash, $m
Cash, $m Operating cash flow — — — — — — (46) (43) (66) (90) (82) +25.0%
Capex — — — — — — 0 0 (2) (1) (1) +115.1%
Free cash flow — — — — — — (46) (43) (67) (91) (82) +25.2%
Balance, $m
Balance, $m Working capital — — — — — — 44 24 52 69 34 +16.0%
Net debt — — — — — — (32) 22 (37) (51) (17) +17.4%
Shareholders’ equity — — — — — — (252) (325) 28 9 (2) n/m
Returns, %
Returns, % ROA — — — — — — 0.00 (137.45) (74.55) (122.85) (146.75) (122.8) pt
ROIC — — — — — — 0.00 0.00 0.00 0.00 0.00 0.0 pt
ROE — — — — — — 0.00 32.65 46.32 (744.17) 1,063.04 (744.2) pt
People
People Employees — — — — — — 94 102 107 100 — +2.1%
Revenue/emp, $m — — — — — — 0.00 0.00 0.00 0.00 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2024 · latest quarter Dec 2024 · fundamentals updated 2 Nov 2026

Fractyl Health, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
NCEL NewcelX Ltd. $15.6M — (loss-making) — — n/m −87.71% (below 0%: shrinking) 0.00% — Compare
RADX Radiopharm Theranostics Limited - Sponsored ADR $14.0M — — — — −137.75% (below 0%: shrinking) — — Compare
CASIF CASI Pharmaceuticals Inc. $12.4M — (loss-making) — (loss-making) −45.93% (below 0%: shrinking) n/m −23,251.69% (below 0%: shrinking) 51.14% (147.67%) Compare
BOLT Bolt Biotherapeutics, Inc. $12.3M — (loss-making) — (loss-making) −99.72% (below 0%: shrinking) n/m +38.87% (above 0%: growing) 100.00% (167,480.00%) Compare
DARE Dare Bioscience, Inc. $12.3M — (loss-making) — (loss-making) +984.43% (above 0%: growing) n/m −30.23% (below 0%: shrinking) (70.56%) (1,582.93%) Compare
GUTS Fractyl Health, Inc. $11.9M — (loss-making) — (loss-making) −57.14% (below 0%: shrinking) n/m +25.34% (above 0%: growing) 100.00% 0.00%
HIND Vyome Holdings, Inc. $11.4M — (loss-making) — (loss-making) −46.00% (below 0%: shrinking) n/m −195.04% (below 0%: shrinking) 43.33% (3,194.81%) Compare
PBM Psyence Biomedical Ltd. $11.2M 0.1× — — n/m −707.20% (below 0%: shrinking) — 0.00% Compare
AEON AEON Biopharma, Inc. $9.4M — (loss-making) — — n/m −76.85% (below 0%: shrinking) — 0.00% Compare
Median of peers $12.3M — — −45.96% — −112.73% 43.33% (865.30%)

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 24 August 2026

Ownership

Directors and executive officers, together 8.36%
Entities affiliated with Nantahala 9.99%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Fractyl Health, Inc. (GUTS) Latest News

26 Feb

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stockrow.com/GUTS · Data as of Nov 2, 2026 · For information only; not investment advice. · © 2026 stockrow.com