Fulcrum Therapeutics, Inc.

FULC Healthcare Biotechnology

Fulcrum Therapeutics, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $80.0 million, up 2,752.0% from fiscal 2023. In the quarter to June 2026, EPS fell 21.4% and free cash flow fell 13.1%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

3.65 0.02 −0.54%
Market cap
$280.0M
P/E
0.0×
Fwd P/E
−9.4×
Dividend yield
—
F-score
5/9
Altman Z
8.22
Beneish M
21.24
Dividend safety
n/a

Insider Decisions trades per month

Total buys 1.49
Total sells 58.98
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — 2 — — —
Sell 1 2 1 1 — — — 1 — — — —
Insider Ownership 3.32%

Capital & Financial Ratios $m

Market Cap 280.01
Revenue 82.51
Net Income (85.00)
Free Cash Flow (65.69)
Net Debt (318.84)
Current Ratio 31.35 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (9.38) (negative: loss-making)
P/S ratio 3.37
P/B ratio 0.90
Past 5Y EPS Growth —
This Y EPS Growth 48.94% (at or above 15%: strong)
Next Y EPS Growth 79.78% (at or above 15%: strong)
Next Y revenue growth (99.72%) (below 0%: weak)
Next 5Y EPS Growth 63.32% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 11.82%
10-year low 10-year high
P/B against its own 10 years 13.54%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2018 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 236 241 352 319
Receivables 1 2 — —
Inventory — — — —
Other — — — —
242 250 357 323
2023 2024 2025 Q'26
Payables 3 1 2 3
ST’ Debt — — — —
Other — — — —
14 11 13 10

Compound Annual Growth %

10y 5y 3y
Sales — — 61.02%
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 29.67% 20.61%

Revenue $m

Mar Jun Sep Dec Year
’26 — — — — —
’24 — 80 — — 80
’23 0 1 1 1 3
’22 3 2 1 1 6
’21 5 4 5 5 19
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (19) (16) — — —
’25 (15) (14) (14) (17) (60)
’24 (25) 59 (19) (17) (2)
’23 (24) (21) (23) (23) (91)
’22 (22) (27) (28) (20) (97)
’21 (16) (18) (23) (22) (78)
’20 (15) (14) (5) (20) (54)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (19) (16) — — —
’25 (15) (14) (14) (17) (60)
’24 (25) 59 (19) (17) (2)
’23 (24) (21) (23) (23) (91)
’22 (22) (29) (28) (20) (99)
’21 (16) (18) (23) (22) (80)
’20 (16) (14) (5) (20) (55)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.25) (0.34) — — —
’25 (0.28) (0.28) (0.31) (0.31) (1.18)
’24 (0.43) 0.87 (0.35) (0.31) (0.16)
’23 (0.41) (0.38) (0.39) (0.40) (1.59)
’22 (0.64) (0.83) (0.51) (0.50) (2.44)
’21 (0.54) (0.60) (0.57) (0.58) (2.29)
’20 (0.81) (0.66) (0.70) (0.64) (2.79)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

4
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low — — — 4.37 7.01 6.85 3.21 2.25 2.86 2.32

Analyst estimates 2026–2028

Powerpack
High — — — 19.30 22.96 33.10 24.79 15.00 13.70 15.74
People
People Employees — — 62 73 73 104 89 76 45 55
Revenue/emp, $m — — 0.00 0.00 0.12 0.18 0.07 0.04 1.78 0.00
Income, $m
Income, $m Revenue — — — — 9 19 6 3 80 —
Gross margin, % — 0.00 0.00 0.00 100.00 100.00 100.00 100.00 100.00 —
EBT — (23) (33) (83) (71) (81) (110) (97) (10) (75)
EBT margin, % — 0.00 0.00 0.00 (802.66) (421.89) (1,732.43) (3,470.05) (12.16) 0.00
Net income — (23) (33) (83) (71) (81) (110) (97) (10) (75)
Depreciation — 1 1 2 2 3 2 2 2 1
Per share, $
Per share, $ Revenue — 0.00 0.00 0.00 0.35 0.54 0.14 0.05 1.29 0.00
Earnings — (32.30) (25.93) (8.13) (2.79) (2.29) (2.44) (1.59) (0.16) (1.18)
Cash flow — (28.23) (17.95) (3.57) (2.12) (2.22) (2.16) (1.48) (0.04) (0.95)
Capex — (2.68) (7.14) (0.08) (0.05) (0.05) (0.04) (0.01) 0.00 0.00
Free cash flow — (30.92) (25.09) (3.65) (2.17) (2.27) (2.20) (1.49) (0.04) (0.95)
Book value — 1.86 60.46 7.89 3.75 5.98 4.42 3.84 3.92 5.51
Shares, m — 1 1 11 25 35 45 61 62 63
Valuation, ×
Valuation, × P/E — — — — 0.00 0.00 0.00 0.00 0.00 —
P/S — — — — 33.65 32.64 56.04 157.59 3.53 —
P/B — — — — 3.12 2.96 1.79 1.88 1.20 —
EV/Sales — — — — 20.85 21.26 24.05 73.38 0.61 —
EV/FCF — — — — (3.35) (5.08) (1.54) (2.25) (20.15) —
Cash, $m
Cash, $m Operating cash flow — (20) (23) (39) (54) (78) (97) (91) (2) (60)
Capex — (2) (9) (1) (1) (2) (2) (1) 0 0
Free cash flow — (22) (32) (40) (55) (80) (99) (91) (2) (60)
Balance, $m
Balance, $m Working capital — (1) 70 88 93 207 191 229 239 344
Total debt — 35 140 0 0 — 13 — — —
Net debt — 0 (73) (97) (113) (218) (203) (236) (241) (352)
Shareholders’ equity — 1 76 87 95 212 199 235 243 349
Returns, %
Returns, % ROA — (56.31) (86.89) (91.54) (59.01) (44.35) (47.60) (40.19) (3.75) (23.89)
ROIC — (1,570.56) (653.65) 0.00 0.00 0.00 0.00 0.00 (679.86) 0.00
ROE — 52.35 80.77 (764.85) (77.68) (52.72) (53.53) (44.84) (4.07) (25.30)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2024 · latest quarter Jun 2024

Charts ten years each

Fulcrum Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
BNTC Benitec Biopharma Limited $295.1M — (loss-making) — (loss-making) −85.42% (below 0%: shrinking) n/m +38.90% (above 0%: growing) 0.00% 0.00% Compare
SRZN Surrozen, Inc. $294.7M — (loss-making) — (loss-making) +408.65% (above 0%: growing) n/m −21.25% (below 0%: shrinking) 100.00% (207.40%) Compare
FULC Fulcrum Therapeutics, Inc. $280.0M — (loss-making) — (loss-making) +27,018.64% (above 0%: growing) n/m −13.05% (below 0%: shrinking) 100.00% 0.00%
OCGN Ocugen, Inc. $275.9M — (loss-making) — (loss-making) +8.38% (above 0%: growing) n/m −13.42% (below 0%: shrinking) 100.00% (1,105.11%) Compare
NAUT Nautilus Biotechnology, Inc. $274.9M — (loss-making) — — n/m −3.16% (below 0%: shrinking) 92.11% (8,296.32%) Compare
IPSC Century Therapeutics, Inc. $271.6M — (loss-making) — (loss-making) +12,667.72% (above 0%: growing) n/m +26.66% (above 0%: growing) 100.00% 0.00% Compare
EYPT EyePoint, Inc. $270.7M — (loss-making) — (loss-making) −90.49% (below 0%: shrinking) n/m +0.41% (above 0%: growing) 100.00% (19,207.10%) Compare
PALI Palisade Bio, Inc. $268.4M 2.2× — (loss-making) +19,900.00% (above 0%: growing) n/m −318.44% (below 0%: shrinking) 100.00% (2,339.60%) Compare
ABEO Abeona Therapeutics Inc. $265.9M — (loss-making) — (loss-making) +225.14% (above 0%: growing) n/m +17.11% (above 0%: growing) 63.30% (119.97%) Compare
Median of peers $273.2M — — +225.14% — −1.38% 100.00% (656.25%)

All 614 Biotechnology stocks →

Fulcrum Therapeutics, Inc. (FULC) key facts

  • Strength: Fulcrum Therapeutics, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $80.0 million, up 2,752.0% from fiscal 2023.
  • Fulcrum Therapeutics, Inc. (FULC) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, FULC traded at $3.65, a market capitalization of $280.0 million.
  • Return on equity was −25.3% and debt-to-equity 0.00.
  • Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 8.22 (safe zone) for fiscal 2024.

Source: company filings (standardised) and stockrow calculations.

Fulcrum Therapeutics, Inc. (FULC) Latest News

stockrow.com/FULC · Data as of Jun 30, 2024 · For information only; not investment advice. · © 2026 stockrow.com