Sunday 18 October 2026
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Fulcrum Therapeutics, Inc.
FULC Healthcare Biotechnology
Fulcrum Therapeutics, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $80.0 million, up 2,752.0% from fiscal 2023. In the quarter to June 2026, EPS fell 21.4% and free cash flow fell 13.1%, each against the same quarter a year earlier. Insiders bought in the last twelve months.
3.65
0.02
−0.54%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | — | — | — | 4.37 | 7.01 | 6.85 | 3.21 | 2.25 | 2.86 | 2.32 |
Analyst estimates 2026–2028 Powerpack |
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| High | — | — | — | 19.30 | 22.96 | 33.10 | 24.79 | 15.00 | 13.70 | 15.74 | |||||
| People | |||||||||||||||
| People | Employees | — | — | 62 | 73 | 73 | 104 | 89 | 76 | 45 | 55 | ||||
| Revenue/emp, $m | — | — | 0.00 | 0.00 | 0.12 | 0.18 | 0.07 | 0.04 | 1.78 | 0.00 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | — | — | — | — | 9 | 19 | 6 | 3 | 80 | — | ||||
| Gross margin, % | — | 0.00 | 0.00 | 0.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | — | |||||
| EBT | — | (23) | (33) | (83) | (71) | (81) | (110) | (97) | (10) | (75) | |||||
| EBT margin, % | — | 0.00 | 0.00 | 0.00 | (802.66) | (421.89) | (1,732.43) | (3,470.05) | (12.16) | 0.00 | |||||
| Net income | — | (23) | (33) | (83) | (71) | (81) | (110) | (97) | (10) | (75) | |||||
| Depreciation | — | 1 | 1 | 2 | 2 | 3 | 2 | 2 | 2 | 1 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | — | 0.00 | 0.00 | 0.00 | 0.35 | 0.54 | 0.14 | 0.05 | 1.29 | 0.00 | ||||
| Earnings | — | (32.30) | (25.93) | (8.13) | (2.79) | (2.29) | (2.44) | (1.59) | (0.16) | (1.18) | |||||
| Cash flow | — | (28.23) | (17.95) | (3.57) | (2.12) | (2.22) | (2.16) | (1.48) | (0.04) | (0.95) | |||||
| Capex | — | (2.68) | (7.14) | (0.08) | (0.05) | (0.05) | (0.04) | (0.01) | 0.00 | 0.00 | |||||
| Free cash flow | — | (30.92) | (25.09) | (3.65) | (2.17) | (2.27) | (2.20) | (1.49) | (0.04) | (0.95) | |||||
| Book value | — | 1.86 | 60.46 | 7.89 | 3.75 | 5.98 | 4.42 | 3.84 | 3.92 | 5.51 | |||||
| Shares, m | — | 1 | 1 | 11 | 25 | 35 | 45 | 61 | 62 | 63 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | — | — | — | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | — | ||||
| P/S | — | — | — | — | 33.65 | 32.64 | 56.04 | 157.59 | 3.53 | — | |||||
| P/B | — | — | — | — | 3.12 | 2.96 | 1.79 | 1.88 | 1.20 | — | |||||
| EV/Sales | — | — | — | — | 20.85 | 21.26 | 24.05 | 73.38 | 0.61 | — | |||||
| EV/FCF | — | — | — | — | (3.35) | (5.08) | (1.54) | (2.25) | (20.15) | — | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | — | (20) | (23) | (39) | (54) | (78) | (97) | (91) | (2) | (60) | ||||
| Capex | — | (2) | (9) | (1) | (1) | (2) | (2) | (1) | 0 | 0 | |||||
| Free cash flow | — | (22) | (32) | (40) | (55) | (80) | (99) | (91) | (2) | (60) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | — | (1) | 70 | 88 | 93 | 207 | 191 | 229 | 239 | 344 | ||||
| Total debt | — | 35 | 140 | 0 | 0 | — | 13 | — | — | — | |||||
| Net debt | — | 0 | (73) | (97) | (113) | (218) | (203) | (236) | (241) | (352) | |||||
| Shareholders’ equity | — | 1 | 76 | 87 | 95 | 212 | 199 | 235 | 243 | 349 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | — | (56.31) | (86.89) | (91.54) | (59.01) | (44.35) | (47.60) | (40.19) | (3.75) | (23.89) | ||||
| ROIC | — | (1,570.56) | (653.65) | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | (679.86) | 0.00 | |||||
| ROE | — | 52.35 | 80.77 | (764.85) | (77.68) | (52.72) | (53.53) | (44.84) | (4.07) | (25.30) | |||||
Negative figures in brackets.
Fiscal years to Dec 2024 · latest quarter Jun 2024
Charts ten years each
Fulcrum Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| BNTC Benitec Biopharma Limited | $295.1M | — (loss-making) | — (loss-making) | −85.42% (below 0%: shrinking) | n/m | +38.90% (above 0%: growing) | 0.00% | 0.00% | Compare |
| SRZN Surrozen, Inc. | $294.7M | — (loss-making) | — (loss-making) | +408.65% (above 0%: growing) | n/m | −21.25% (below 0%: shrinking) | 100.00% | (207.40%) | Compare |
| FULC Fulcrum Therapeutics, Inc. | $280.0M | — (loss-making) | — (loss-making) | +27,018.64% (above 0%: growing) | n/m | −13.05% (below 0%: shrinking) | 100.00% | 0.00% | |
| OCGN Ocugen, Inc. | $275.9M | — (loss-making) | — (loss-making) | +8.38% (above 0%: growing) | n/m | −13.42% (below 0%: shrinking) | 100.00% | (1,105.11%) | Compare |
| NAUT Nautilus Biotechnology, Inc. | $274.9M | — (loss-making) | — | — | n/m | −3.16% (below 0%: shrinking) | 92.11% | (8,296.32%) | Compare |
| IPSC Century Therapeutics, Inc. | $271.6M | — (loss-making) | — (loss-making) | +12,667.72% (above 0%: growing) | n/m | +26.66% (above 0%: growing) | 100.00% | 0.00% | Compare |
| EYPT EyePoint, Inc. | $270.7M | — (loss-making) | — (loss-making) | −90.49% (below 0%: shrinking) | n/m | +0.41% (above 0%: growing) | 100.00% | (19,207.10%) | Compare |
| PALI Palisade Bio, Inc. | $268.4M | 2.2× | — (loss-making) | +19,900.00% (above 0%: growing) | n/m | −318.44% (below 0%: shrinking) | 100.00% | (2,339.60%) | Compare |
| ABEO Abeona Therapeutics Inc. | $265.9M | — (loss-making) | — (loss-making) | +225.14% (above 0%: growing) | n/m | +17.11% (above 0%: growing) | 63.30% | (119.97%) | Compare |
| Median of peers | $273.2M | — | — | +225.14% | — | −1.38% | 100.00% | (656.25%) |
Fulcrum Therapeutics, Inc. (FULC) key facts
- Strength: Fulcrum Therapeutics, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $80.0 million, up 2,752.0% from fiscal 2023.
- Fulcrum Therapeutics, Inc. (FULC) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, FULC traded at $3.65, a market capitalization of $280.0 million.
- Return on equity was −25.3% and debt-to-equity 0.00.
- Its Piotroski F-score is 5 out of 9 and its Altman Z-score is 8.22 (safe zone) for fiscal 2024.