Saturday 17 October 2026
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Clene Inc.
CLNN Healthcare Biotechnology
Clene Inc.’s revenue for fiscal 2025 (year ended December 2025) was $200,000.00, down 41.5% from fiscal 2024. In the quarter to June 2026, revenue grew 233.3%, EPS fell 38.5%, free cash flow grew 45.4% and total debt rose 16.2%, each against the same quarter a year earlier. Operating cash flow growth for three consecutive years; insiders bought in the last twelve months.
3.10
0.21
−6.34%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | — | — | 193.00 | 198.00 | 206.00 | 75.60 | 17.40 | 5.00 | 3.82 | 2.28 |
Analyst estimates 2026–2028 Powerpack |
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| High | — | — | 199.00 | 210.00 | 350.00 | 356.40 | 102.60 | 39.80 | 11.00 | 13.50 | |||||
| People | |||||||||||||||
| People | Employees | — | — | — | — | 74 | 102 | 86 | 85 | 76 | 79 | ||||
| Revenue/emp, $m | — | — | — | — | 0.00 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | — | — | — | — | 0 | 1 | 0 | 1 | 0 | 0 | ||||
| Gross margin, % | — | — | — | 0.00 | 68.45 | 60.03 | 94.50 | 81.50 | 79.53 | 78.50 | |||||
| EBT | — | 0 | 0 | (16) | (19) | (10) | (30) | (50) | (39) | (26) | |||||
| EBT margin, % | — | 0.00 | 0.00 | 0.00 | (9,160.68) | (1,406.36) | (6,325.16) | (7,569.42) | (11,520.47) | (13,086.50) | |||||
| Net income | — | 0 | 0 | (16) | (19) | (10) | (30) | (50) | (39) | (26) | |||||
| Depreciation | — | 0 | — | 1 | 1 | 1 | 1 | 2 | 2 | 1 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | — | 0.00 | 0.00 | 0.00 | 0.24 | 0.23 | 0.15 | 0.12 | 0.05 | 0.02 | ||||
| Earnings | — | 0.00 | (4.00) | (18.61) | (22.00) | (3.20) | (9.20) | (9.40) | (5.67) | (2.65) | |||||
| Cash flow | — | 0.00 | (3.02) | (15.21) | (21.63) | (11.25) | (11.97) | (5.75) | (3.07) | (1.88) | |||||
| Capex | — | 0.00 | 0.00 | (0.34) | (0.44) | (0.43) | (1.59) | (0.06) | 0.00 | 0.00 | |||||
| Free cash flow | — | 0.00 | (3.02) | (15.54) | (22.07) | (11.68) | (13.55) | (5.81) | (3.07) | (1.89) | |||||
| Book value | — | 0.00 | 73.64 | (78.09) | 0.39 | 4.09 | 0.99 | 2.55 | (1.27) | (1.78) | |||||
| Shares, m | — | 2 | 0 | 1 | 1 | 3 | 3 | 5 | 7 | 10 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | — | — | — | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | — | — | — | — | 919.38 | 349.08 | 130.96 | 46.53 | 107.97 | 289.36 | |||||
| P/B | — | — | — | — | 555.41 | 20.04 | 19.14 | 2.27 | 0.00 | 0.00 | |||||
| EV/Sales | — | — | — | — | 642.10 | 306.06 | 122.45 | 11.45 | 117.53 | 331.12 | |||||
| EV/FCF | — | — | — | — | (6.85) | (6.15) | (1.31) | (0.25) | (1.88) | (3.56) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | — | 0 | 0 | (13) | (19) | (35) | (39) | (30) | (21) | (19) | ||||
| Capex | — | 0 | — | 0 | 0 | (1) | (5) | 0 | 0 | 0 | |||||
| Free cash flow | — | 0 | 0 | (13) | (19) | (36) | (44) | (31) | (21) | (19) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | — | 0 | 1 | 5 | 51 | 49 | 15 | 14 | 6 | (2) | ||||
| Total debt | — | — | — | 1 | 2 | 19 | 19 | 12 | 15 | 14 | |||||
| Net debt | — | — | (1) | (8) | (57) | (31) | (4) | (23) | 3 | 8 | |||||
| Shareholders’ equity | — | 0 | 5 | (68) | 0 | 13 | 3 | 13 | (9) | (18) | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | — | 0.00 | (1.17) | (52.08) | (46.38) | (14.84) | (55.63) | (102.25) | (98.90) | (115.13) | ||||
| ROIC | — | 0.00 | (4.76) | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| ROE | — | 0.00 | (11.10) | 51.47 | 57.17 | (150.56) | (377.90) | (595.47) | (1,738.36) | 197.91 | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Clene Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| HOWL Werewolf Therapeutics, Inc. | $48.5M | — (loss-making) | — (loss-making) | +256.11% (above 0%: growing) | n/m | +146.46% (above 0%: growing) | 100.00% | 34.09% | Compare |
| ELTX Elicio Therapeutics, Inc. | $48.2M | — (loss-making) | — (loss-making) | −55.27% (below 0%: shrinking) | n/m | +8.77% (above 0%: growing) | 0.00% | 0.00% | Compare |
| ACET Adicet Bio, Inc. | $48.1M | — (loss-making) | — (loss-making) | +727.73% (above 0%: growing) | n/m | +24.94% (above 0%: growing) | 0.00% | 0.00% | Compare |
| KLRS Kalaris Therapeutics Inc. | $47.8M | — (loss-making) | — | — | n/m | +11.91% (above 0%: growing) | 0.00% | 0.00% | Compare |
| IBIO iBio, Inc. | $47.6M | — (loss-making) | — (loss-making) | +100.00% (above 0%: growing) | n/m | −35.33% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| CLNN Clene Inc. | $47.0M | — (loss-making) | — (loss-making) | +233.33% (above 0%: growing) | n/m | +45.43% (above 0%: growing) | 60.00% | (5,941.11%) | |
| TVGN Tevogen Inc. | $46.1M | — (loss-making) | — | — | n/m | +5.78% (above 0%: growing) | — | 0.00% | Compare |
| INMB INmune Bio, Inc. | $45.8M | — (loss-making) | — (loss-making) | +8.70% (above 0%: growing) | n/m | +55.39% (above 0%: growing) | 100.00% | 0.00% | Compare |
| IMA ImageneBio, Inc. | $45.7M | — (loss-making) | — (loss-making) | −60.08% (below 0%: shrinking) | n/m | +23.76% (above 0%: growing) | 100.00% | 0.00% | Compare |
| Median of peers | $47.7M | — | — | +54.35% | — | +17.84% | 100.00% | 0.00% |
Clene Inc. (CLNN) key facts
- Concern: Clene Inc.’s revenue for fiscal 2025 (year ended December 2025) was $200,000.00, down 41.5% from fiscal 2024.
- Clene Inc. (CLNN) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, CLNN traded at $3.10, a market capitalization of $47.0 million.
- Return on equity was 197.9% and debt-to-equity -0.74.
- Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −27.14 (distress zone) for fiscal 2025.