Codexis, Inc.

CDXS

Healthcare Biotechnology

Codexis, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $70.4 million, up 18.6% from fiscal 2024.

Revenue
−2.69%
EPS
+18.8%
Free cash flow
+48.6%
Total debt
−14.1%

Quarter to June 2026, against a year earlier

0.97 0.03 −3.00%
Market cap
$109.5M
P/E
n/m
Fwd P/E
n/m
Dividend yield
—
F-score
4/9
ROIC
−151.2%
Net debt / EBITDA
1.1×
Dividend safety
n/a

Codexis, Inc. (CDXS) Return on invested capital

Alert me on Return on invested capital

Codexis, Inc.'s return on invested capital over the twelve months to 30 June 2026 was −151.2%, up 67.2 percentage points from fiscal 2025 (−218.4%). Over the past ten years it has ranged from −719.4% (fiscal 2016) to 0.00% (fiscal 2017); the current reading is higher than 27% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Return on invested capital, annual

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Annual newest first

Period Return on invested capital Change (points)
FY2025 −218.4% (51.13)
FY2024 −167.2% 35.55
FY2023 −202.8% (170.99)
FY2022 −31.8% (16.13)
FY2021 −15.7% 20.22
FY2020 −35.9% (15.93)
FY2019 −20.0% 189.96
FY2018 −209.9% (209.91)
FY2017 0.00% 719.42
FY2016 −719.4% (189.26)

Against its own ten years

Low −719.4% High 0.00%
Ten-year median −167.2%
Current reading's percentile 27

Return on invested capital against peers

Company Return on invested capital
ENGN enGene Therapeutics Inc compare 0.00%
ANIX ANIXA BIOSCIENCES INC compare 0.00%
AVXL Anavex Life Sciences Corp. compare 0.00%
IMUX Immunic, Inc. compare 0.00%
FHTX Foghorn Therapeutics Inc. compare 0.00%
OTLK Outlook Therapeutics, Inc. compare 0.00%
PDSB PDS Biotechnology Corporation compare 0.00%
CDXS Codexis, Inc. −151.2%
VYGR Voyager Therapeutics, Inc. compare −249.6%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Return on invested capital is

Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.

TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)

The full definition of Return on invested capital →

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