C4 Therapeutics, Inc.

CCCC

Healthcare Biotechnology

C4 Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $35.9 million, up 1.02% from fiscal 2024.

Revenue
−24.6%
EPS
+63.5%
Free cash flow
+17.9%

Quarter to September 2026, against a year earlier

2.74 0.15 −5.19%
Market cap
$379.5M
P/E
n/m
Fwd P/E
n/m
Dividend yield
—
F-score
4/9
ROIC
−279.8%
Net debt / EBITDA
2.1×
Dividend safety
n/a

C4 Therapeutics, Inc. (CCCC) Return on invested capital

Alert me on Return on invested capital

C4 Therapeutics, Inc.'s return on invested capital over the twelve months to 30 September 2026 was −279.8%, up 614.8 percentage points from fiscal 2025 (−894.6%). Over the past ten years it has ranged from −894.6% (fiscal 2025) to 0.00% (fiscal 2024) — the current reading is the lowest in ten years. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Return on invested capital, annual

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Annual newest first

Period Return on invested capital Change (points)
FY2025 −894.6% (894.58)
FY2024 0.00% 0.00
FY2023 0.00% 329.60
FY2022 −329.6% (274.06)
FY2021 −55.5% (55.54)
FY2020 0.00% 0.00
FY2019 0.00% 0.00
FY2018 0.00% —

Against its own ten years

Low −894.6% High 0.00%
Ten-year median 0.00%
Current reading's percentile 13

Return on invested capital against peers

Company Return on invested capital
ALEC Alector, Inc. compare 0.00%
RZLT Rezolute, Inc. compare 0.00%
EDIT Editas Medicine, Inc. compare 0.00%
SRZN Surrozen, Inc. compare 0.00%
ALT Altimmune, Inc. compare −34.3%
AVTX Avalo Therapeutics, Inc. compare −137.8%
CCCC C4 Therapeutics, Inc. −279.8%
MPLT MapLight Therapeutics, Inc. compare −348.4%
LYEL Lyell Immunopharma, Inc. compare −1,070.8%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Return on invested capital is

Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.

TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)

The full definition of Return on invested capital →

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