Avalo Therapeutics, Inc. AVTX

15.47 (0.25) (1.59%) as of 25 Sep
Market cap
$843.1M
P/E
0.0×

Insider Decisions

Total sells 8.50
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — — — — — —
Sell — 1 — — — 1 4 7 2 1 5 2
Insider Ownership 0.00%

Capital & Financial Ratios

Market Cap 843.06
Revenue 1.25
Net Income (100.33)
Free Cash Flow (68.29)
Net Debt (400.32)
Current Ratio 19.31
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 540.92
P/B ratio 1.50
Past 5Y EPS Growth 56.49%
This Y EPS Growth 50.96%
Next Y EPS Growth (3.97%)
Next 5Y EPS Growth 16.97%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2028 Powerpack
2027 Powerpack
2026 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 7 135 98 400
Receivables 0 1 — —
Inventory — — — —
Other — — — —
8 139 105 408
2023 2024 2025 Q'26
Payables 0 0 0 3
ST’ Debt — — — —
Other — 0 — —
5 7 13 21
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — (61.19%) (85.16%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 20.30% 27.59% 0.00%

Revenue

Mar Jun Sep Dec Year
’26 — — — — —
’25 — — — — 0
’24 — — 0 0 0
’23 0 1 0 1 2
’22 1 1 15 1 18
’21 0 3 1 0 5
’20 3 1 1 1 7
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (18) (20) — — —
’25 (9) (11) (16) (14) (51)
’24 (6) (16) (12) (15) (49)
’23 (10) (11) (7) (3) (31)
’22 (16) (12) 6 (4) (27)
’21 (18) (19) (16) (17) (71)
’20 (6) (9) (12) (14) (41)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (18) (20) — — —
’25 (9) (82) (16) (14) (51)
’24 (6) (16) (12) (15) (49)
’23 (10) (11) (7) (3) (31)
’22 (16) (13) 6 (4) (27)
’21 (18) (19) (16) (17) (71)
’20 (6) (9) (12) (14) (41)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (0.98) (0.83) — — —
’25 (1.25) (1.92) (2.19) (0.37) (5.84)
’24 (141.00) (14.07) (2.83) 121.45 (4.69)
’23 (202.38) (140.48) (26.19) 258.32 (114.00)
’22 (571.66) (328.57) 80.95 (247.62) (1.05k)
’21 (914.65) (514.49) (485.91) (392.83) (2.37k)
’20 (971.82) (543.07) (485.91) (484.51) (2.46k)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
2,183.04 979.20 6,278.40 8,380.80 4,377.60 4,608.00 581.76 7.92 3.95 3.39

Analyst estimates 2026–2028

Powerpack
Low Price
16,128.00 12,240.00 16,528.32 22,032.00 15,465.60 12,960.00 5,414.40 1,296.00 34.46 20.72
High Price
15 38 64 18 32 44 20 19 23 33
Employees
0 1 0 0 0 0 1 0 0 0
Revenue/Emp
1 28 7 7 7 5 18 2 0 0
Revenue
100.00% 97.71% 53.61% 108.39% 95.52% 72.38% 80.98% 33.26% 182.99% 100.00%
Gross Margin
(16) 14 (35) (16) (67) (85) (42) (32) (35) (78)
EBT
(1,428.59%) 49.75% (502.58%) (236.88%) (1,002.79%) (1,566.23%) (230.62%) (1,638.77%) (7,939.91%) (132,362.71%)
EBT Margin
(16) 12 (40) (16) (63) (84) (42) (32) (35) (78)
Net Income
0 1 7 5 2 2 2 6 0 0
Depreciation
371.94 4,345.80 576.10 450.03 287.51 154.23 460.48 6.93 0.10 0.00
Revenue/Sh
(5,344.99) 1,200.48 (3,174.71) (1,071.41) (2,458.13) (2,372.38) (1,054.76) (114.00) (7.94) (5.84)
Earnings/Sh
(4,701.00) 1,965.44 (256.40) (1,275.62) (1,739.87) (2,025.49) (682.42) (110.48) (11.08) (3.84)
Cash Flow/Sh
(11.26) (3.64) (46.26) (17.47) (2.70) (3.23) (2.42) 0.09 0.00 0.00
Capex/Sh
(4,712.26) 1,961.80 (302.66) (1,293.09) (1,742.58) (2,028.71) (684.85) (110.39) (11.08) (3.84)
Free CF/Sh
66.77 4,353.06 1,713.75 1,399.71 1,054.16 659.49 (278.44) 26.30 30.06 6.20
Book Value/Sh
0 0 0 0 0 0 0 0 4 13
Shares
0.00 7.70 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
PE Ratio
0.00 2.21 16.15 34.49 26.44 31.75 2.61 1.26 26.37 195.21
PS Ratio
38.39 2.20 5.43 11.09 7.21 7.42 0.00 0.33 0.25 2.93
PB Ratio
0.00 2.16 16.82 35.09 24.13 27.80 2.99 (1.56) (79.94) 117.92
EV/Sales
(0.40) 4.79 (32.01) (12.21) (3.98) (2.11) (2.01) 0.10 2.03 (1.20)
EV/FCF
(15) 13 (3) (19) (41) (71) (27) (31) (49) (51)
Op' Cash Flow
0 0 (1) 0 0 0 0 0 — —
Capex
(15) 13 (4) (19) (41) (71) (27) (31) (49) (51)
FCF
1 0 (4) 6 11 42 (6) 4 132 92
Working Cap'
2 — 15 1 3 33 20 — — —
Total Debt
(3) (2) 5 (10) (15) (21) 7 (7) (135) (98)
Net Debt
0 28 21 21 25 23 (11) 7 133 83
Sh' Equity
(120.11%) 32.00% (70.85%) (30.22%) (159.02%) (136.12%) (73.35%) (116.06%) (40.91%) (58.58%)
ROA
0.00% 34.20% (86.30%) (91.63%) (501.97%) (2,910.08%) 0.00% 0.00% 0.00% 0.00%
ROIC
(247.87%) 55.38% (164.27%) (76.72%) (278.79%) (354.20%) (684.77%) 1,747.11% (50.06%) (72.43%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2025 · latest quarter Dec 2024

Avalo Therapeutics, Inc. peers in Biotechnology

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Avalo Therapeutics, Inc. (AVTX) key facts

  • Avalo Therapeutics, Inc. (AVTX) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • Avalo Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $59,000.00, down 86.6% from fiscal 2024.
  • As of September 25, 2026, AVTX traded at $15.47, a market capitalization of $843.1 million.
  • Return on equity was −72.4% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Avalo Therapeutics, Inc. (AVTX) Latest News

News by impact score

Fine-tune

23 Sep

4

Avalo Therapeutics announced a late-breaker oral presentation and poster at the EADV 2026 Congress in Vienna (Sept. 30–Oct. 3). The oral session (Hall A, Oct. 1 at 5:00 p.m. CEST) will present efficacy and safety of Abdakibart (ABD), a humanized high-affinity anti-IL-1β IgG4 mAb, in the Phase 2 LOTUS trial for moderate-to-severe hidradenitis suppurativa, including IHS4 subgroup and lesion-type analyses at Week 16. The poster (Sept. 30, 7:00 a.m. CEST) will report primary LOTUS results. Avalo says Abdakibart is advancing toward a Phase 3 registrational program in HS; it is also developing AVTX-010, a long-acting next-generation anti-IL-1β mAb. The event underscores Avalo's focus on IL-1β–driven inflammatory diseases and ongoing expansion of its HS program. Signals a major strategic milestone toward a Phase 3 HS program, likely affecting investor sentiment and future performance.

11 Aug

3

Avalo Therapeutics reports widening losses with improved EPS, raising questions of a potential strategy shift. Mixed earnings metrics signal possible strategic adjustments with moderate effects on near-term performance and sentiment.

6 Aug

3

Avalo Therapeutics reported second quarter 2026 financial results and recent business updates. Quarterly financial results and business updates deliver performance data that can shift near-term investor sentiment without altering long-term company trajectory.

16 Jun

4

Avalo Therapeutics adds AVTX-010, a long-acting next-generation anti-IL-1β antibody, to its pipeline. Pipeline addition of AVTX-010 marks major strategic product development step for Avalo.

13 May

3

Avalo Therapeutics reported first quarter 2026 financial results and recent business updates. Quarterly financial results and business updates moderately influence financial performance and investor sentiment.

6 May

4

Avalo Therapeutics, Inc. (AVTX), a small biotech challenging AbbVie, Novartis, and Sanofi, has catapulted into a breakout amid promising developments. AVTX's breakout positioning it against pharma giants like AbbVie, Novartis, and Sanofi promises major shifts in competitive dynamics and investor sentiment.

4

Avalo Therapeutics (AVTX) shares spiked on positive data from its skin drug; BioNTech announced staff cuts. Positive skin drug data triggered share spike, indicating strong clinical progress with potential to enhance competitive position and investor sentiment.

5 May

5

Avalo Therapeutics priced an underwritten public offering of 150 million shares of common stock at $2.50 per share, expecting gross proceeds of $375 million before expenses. A $375 million capital raise equips Avalo Therapeutics with transformative funding for clinical trials and operations, fundamentally enhancing long-term prospects and market position.

5

Avalo Therapeutics achieves positive topline results in Phase 2 LOTUS trial of abdakibart (AVTX-009) for moderate to severe hidradenitis suppurativa. Positive Phase 2 topline results for abdakibart in hidradenitis suppurativa mark a pivotal clinical milestone poised to redefine AVTX's pipeline, competitive position, and long-term market prospects.

4

Avalo Therapeutics, Inc. (AVTX) announces a proposed public offering of common stock and pre-funded warrants to raise capital. Public offering provides essential funding for operations but dilutes shareholders, significantly affecting financial position and stock performance.

28 Apr

3

Avalo Therapeutics, Inc. (AVTX) purchases optional milestone buyout. Purchasing the optional milestone buyout streamlines Avalo's financial commitments and mitigates future development risks.

6 Apr

3

Avalo Therapeutics (NASDAQ:AVTX) is well-positioned to execute its growth plans. Strong positioning for growth signals moderate influence on financial performance and investor sentiment.

3 Apr

4

Wall Street analysts predict 113.34% upside for Avalo Therapeutics (AVTX) stock, based on strong buy ratings and optimistic price targets amid promising clinical developments. Analyst consensus forecasting 113.34% upside highlights significant potential to drive investor sentiment and stock trajectory.

23 Mar

4

Avalo Therapeutics reported 2025 financial results and provided recent business updates. Financial results announcements and business updates often trigger significant shifts in investor sentiment and stock trajectory for biotechs.

12 Mar

4

Avalo Therapeutics CEO teases Q2 top-line data for AVTX-009 Phase 2b HS LOTUS Trial at conference. Teasing Phase 2b top-line data for lead anti-inflammatory candidate AVTX-009 signals potential pipeline advancement and major stock catalyst.

5 Mar

4

Avalo Therapeutics presented its AVTX-009 development plan and near-term Phase II data for hidradenitis suppurativa at a healthcare conference. Near-term Phase II HS data and AVTX-009 plans represent major clinical milestones likely to significantly influence investor sentiment and stock trajectory.

25 Feb

4

Avalo Therapeutics highlighted the upcoming Phase II catalyst for AVTX-009 in hidradenitis suppurativa and its extended cash runway during the Oppenheimer Conference presentation. Upcoming Phase II data readout for AVTX-009 and sufficient cash runway represent major catalysts that could significantly enhance investor sentiment and company trajectory.

11 Feb

4

Avalo Therapeutics, Inc. announced plans for a Phase IIb LOTUS readout for its drug AVTX-009 targeting Hidradenitis Suppurativa, expected in Q2 2026. This development is part of the company's ongoing efforts to advance its pipeline and address unmet medical needs in this chronic skin condition. The upcoming Phase IIb readout could significantly influence Avalo's product development and market positioning in a niche therapeutic area.

6 Nov

3

Avalo Therapeutics, Inc. reported its financial results for the third quarter of 2025, highlighting key business updates and financial metrics. The company detailed its revenue performance, expenses, and strategic initiatives aimed at advancing its product pipeline. Management provided insights into ongoing clinical trials and future plans, emphasizing commitment to innovation and growth in the biopharmaceutical sector. Financial results and updates on clinical trials indicate a moderately noticeable influence on the company's future performance.

29 Oct

4

Piper Sandler has reaffirmed a bullish price target of $48 for Avalo Therapeutics, Inc. (AVTX), indicating strong confidence in the company's future performance and potential growth. This endorsement reflects positive sentiment surrounding Avalo's strategic direction and market positioning. A bullish price target from a reputable analyst suggests significant confidence in Avalo's future performance and market dynamics.

4

Avalo Therapeutics, Inc. has completed enrollment in its Phase 2 LOTUS Trial for AVTX-009, a treatment aimed at addressing Hidradenitis Suppurativa. This trial is a significant step in evaluating the efficacy and safety of AVTX-009 for patients suffering from this chronic skin condition. Completion of enrollment in a Phase 2 trial is a critical milestone that could significantly influence Avalo's future product development and market positioning.

28 Oct

4

Avalo Therapeutics, Inc. is positioned to drive business growth, supported by its financial stability and strategic initiatives. The company has sufficient resources to invest in product development and expand its market presence, which could enhance its competitive edge. Analysts express optimism about Avalo's potential to leverage its assets for future advancements. Avalo's strategic initiatives and financial stability are likely to significantly impact its future performance and market positioning.

1 Oct

3

Avalo Therapeutics, Inc. has announced the expansion of its leadership team with key appointments in business development and human resources. These strategic hires are aimed at enhancing the company's operational capabilities and driving growth initiatives. Leadership changes can moderately influence the company's strategic direction and operational effectiveness.

22 Sep

3

Avalo Therapeutics, Inc. has appointed Kevin R. Lind to its Board of Directors, enhancing the board's expertise and governance. Lind brings extensive experience in the biotechnology sector, having held leadership roles in various companies. His appointment is expected to support Avalo's strategic initiatives and growth in the biopharmaceutical industry. The addition of a seasoned executive to the board may positively influence Avalo's strategic direction and operational effectiveness.

14 Sep

3

Institutional investors hold a significant 34% stake in Avalo Therapeutics, Inc. (NASDAQ:AVTX), indicating strong interest and potential influence on the company's strategic direction and market performance. The substantial institutional ownership may moderately influence investor sentiment and the company's financial performance.

7 Aug

3

Avalo Therapeutics, Inc. reported its financial results for the second quarter of 2025, highlighting key business updates and developments. The company detailed its revenue performance, expenses, and strategic initiatives aimed at advancing its pipeline. Management provided insights into ongoing clinical trials and collaborations, emphasizing their commitment to innovation in therapeutic solutions. The report reflects Avalo's efforts to enhance shareholder value and position itself within the competitive landscape of biotechnology. The financial results and updates indicate moderate influence on Avalo's market positioning and operational focus.

2 Jul

4

Avalo Therapeutics, Inc. (NASDAQ:AVTX) appointed Dr. Rita Jain to its Board of Directors as the company advances its Phase 2 LOTUS trial in HS, with results expected in mid-2026. Avalo will participate in upcoming virtual conferences in 2025. H.C. Wainwright analysts upgraded Avalo to Buy with a 12-month price target of $15.00, suggesting over 200% upside, driven by the potential of its leading candidate, AVTX-009, a monoclonal antibody targeting interleukin-1ß. The appointment of Dr. Jain and the advancement of the LOTUS trial are significant strategic moves that could greatly influence Avalo's future performance and market perception.

18 Jun

4

Avalo Therapeutics, Inc. has appointed Rita Jain, M.D. to its Board of Directors. Dr. Jain brings over two decades of experience in biopharmaceutical development and clinical strategy, having previously held leadership roles at ChemoCentryx and Akebia Therapeutics. Her expertise will support Avalo's ongoing Phase 2 trial of AVTX-009, an anti-IL-1β monoclonal antibody for hidradenitis suppurativa, which is expected to read out results in mid-2026. Avalo aims to address unmet needs in inflammatory diseases with this treatment. The appointment of Dr. Jain is a significant strategic move that could enhance Avalo's development capabilities and market positioning.

26 Mar

3

Avalo Therapeutics, Inc. has appointed Michael Heffernan as the new Chairman of the Board. Heffernan brings extensive experience in the biopharmaceutical industry, having previously held leadership roles at various companies. His appointment is expected to strengthen Avalo's strategic direction and governance as the company continues to focus on developing innovative therapies. The appointment of a seasoned industry leader may positively influence Avalo's strategic direction and governance, impacting its competitive positioning.

20 Mar

4

Avalo Therapeutics, Inc. reported its 2024 financial results, highlighting a cash balance of approximately $135 million, expected to fund operations into at least 2027. The company initiated the Phase 2 LOTUS trial for AVTX-009, targeting hidradenitis suppurativa, with topline data anticipated in 2026. Jennifer Riley was appointed as Chief Strategy Officer to guide strategy and pipeline planning. Research and development expenses rose to $24.4 million, while the net loss for 2024 was $35.1 million, an increase from the previous year. The initiation of the Phase 2 LOTUS trial and the appointment of a Chief Strategy Officer are significant strategic moves that could greatly influence Avalo's future performance and market positioning.

stockrow.com/AVTX · Data as of Dec 31, 2024 · For information only; not investment advice. · © 2026 stockrow.com