BioCryst Pharmaceuticals, Inc.

BCRX Healthcare Drug Manufacturers Specialty & Generic

BioCryst Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $874.8 million, up 94.1% from fiscal 2024.

Revenue
+13.1%
EPS
+150.0%
Free cash flow
−18.7%
Total debt
+15.2%

Quarter to September 2026, against a year earlier

7.55 0.69 −8.37%
Market cap
$2.0B
P/E
0.0×
Fwd P/E
−3.7×
Dividend yield
—
F-score
7/9
Altman Z
1.83
Beneish M
−2.27
Dividend safety
n/a
Dec '25 Dec '24 Dec '23 Dec '22 Dec '21 Dec '20 Dec '19 Dec '18 Dec '17 Dec '16
P/E ratio
6.24 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Piotroski F-Score
7 3 4 3 5 2 3 2 5 2
P/S ratio
1.87 3.45 3.52 7.86 15.78 69.96 8.17 40.32 18.24 17.79
Altman Z-Score
1.83 (2.55) (3.06) (1.69) (0.52) (3.06) (6.07) (3.47) (2.91) (6.97)
P/FCF ratio
4.74 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Altman Z″-Score (non-manufacturers)
(2.63) (8.82) (8.05) (5.90) (3.73) (9.26) (16.46) (18.03) (10.93) (23.23)
Beneish M-Score
(2.27) (0.91) (3.82) (2.23) 4.12 (4.64) (0.91) (3.57) (3.09) (2.04)
P/Operating CF
5.61 (298.17) (130.82) (89.26) (76.43) (29.30) (38.17) (34.72) (43.67) (80.07)
P/B ratio
0.00 0.00 0.00 0.00 0.00 0.00 10.43 16.91 5.48 297.04
EV/Sales
2.11 4.58 4.87 9.01 16.31 68.66 6.45 36.77 14.60 16.62
EV/EBITDA
5.45 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
EV/FCF
5.34 (38.84) (16.58) (14.95) (17.73) (9.02) (3.50) (8.17) (8.87) (7.46)
Current Ratio
2.06 2.63 3.31 4.90 5.46 3.06 1.78 1.65 1.68 1.23
Net Debt/EBITDA
0.61 (39.91) (3.98) (2.09) (0.47) 0.13 0.85 0.79 1.65 0.05
Debt/Equity
(4.04) (1.75) (1.84) (2.50) (5.54) (14.51) 1.40 0.66 0.31 34.05
ROE
(88.68%) 19.08% 60.40% 123.07% 291.59% (1,925.37%) (248.94%) (152.26%) (154.16%) (223.70%)
ROA
52.53% (17.65%) (42.46%) (43.42%) (39.89%) (71.69%) (67.61%) (62.29%) (49.07%) (51.97%)
ROIC
245.61% (4.71%) 0.00% (544.24%) 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Tangible Assets
121.56% (33.00%) (64.01%) (58.89%) (39.07%) (81.16%) (137.22%) (187.47%) (109.45%) (244.55%)
Average Days of Receivables
44.57 64.03 62.72 68.19 68.31 177.17 165.52 75.87 88.65 121.44
Earnings Yield
16.03% (5.72%) (19.44%) (11.62%) (7.44%) (14.50%) (28.41%) (12.14%) (14.34%) (11.79%)
Free Cash Flow Yield
21.10% (3.42%) (8.34%) (7.67%) (5.83%) (10.88%) (22.55%) (11.16%) (9.02%) (12.53%)
Free Cash Flow per Share
1.65 (0.26) (0.51) (0.88) (0.81) (0.81) (0.78) (0.90) (0.49) (0.80)
Book value per Share
(0.57) (2.30) (2.37) (1.58) (0.60) (0.12) 0.33 0.48 0.99 0.02
Free Cash Flow
345.45 (53.14) (97.31) (163.20) (144.54) (135.62) (89.93) (92.93) (41.46) (58.71)
EV/EBIT
5.41 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
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Columns are period end dates · fundamentals updated 4 Nov 2026