BioCryst Pharmaceuticals, Inc.

BCRX Healthcare Drug Manufacturers Specialty & Generic

BioCryst Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $874.8 million, up 94.1% from fiscal 2024.

Revenue
+13.1%
EPS
+150.0%
Free cash flow
−18.7%
Total debt
+15.2%

Quarter to September 2026, against a year earlier

7.55 0.69 −8.37%
Market cap
$2.0B
P/E
0.0×
Fwd P/E
−3.7×
Dividend yield
—
F-score
7/9
Altman Z
1.83
Beneish M
−2.27
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
P/E ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 6.24
Piotroski F-Score
2 5 2 3 2 5 3 4 3 7
P/S ratio
17.79 18.24 40.32 8.17 69.96 15.78 7.86 3.52 3.45 1.87
Altman Z-Score
(6.97) (2.91) (3.47) (6.07) (3.06) (0.52) (1.69) (3.06) (2.55) 1.83
P/FCF ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 4.74
Altman Z″-Score (non-manufacturers)
(23.23) (10.93) (18.03) (16.46) (9.26) (3.73) (5.90) (8.05) (8.82) (2.63)
Beneish M-Score
(2.04) (3.09) (3.57) (0.91) (4.64) 4.12 (2.23) (3.82) (0.91) (2.27)
P/Operating CF
(80.07) (43.67) (34.72) (38.17) (29.30) (76.43) (89.26) (130.82) (298.17) 5.61
P/B ratio
297.04 5.48 16.91 10.43 0.00 0.00 0.00 0.00 0.00 0.00
EV/Sales
16.62 14.60 36.77 6.45 68.66 16.31 9.01 4.87 4.58 2.11
EV/EBITDA
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.45
EV/FCF
(7.46) (8.87) (8.17) (3.50) (9.02) (17.73) (14.95) (16.58) (38.84) 5.34
Current Ratio
1.23 1.68 1.65 1.78 3.06 5.46 4.90 3.31 2.63 2.06
Net Debt/EBITDA
0.05 1.65 0.79 0.85 0.13 (0.47) (2.09) (3.98) (39.91) 0.61
Debt/Equity
34.05 0.31 0.66 1.40 (14.51) (5.54) (2.50) (1.84) (1.75) (4.04)
ROE
(223.70%) (154.16%) (152.26%) (248.94%) (1,925.37%) 291.59% 123.07% 60.40% 19.08% (88.68%)
ROA
(51.97%) (49.07%) (62.29%) (67.61%) (71.69%) (39.89%) (43.42%) (42.46%) (17.65%) 52.53%
ROIC
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% (544.24%) 0.00% (4.71%) 245.61%
Return on Tangible Assets
(244.55%) (109.45%) (187.47%) (137.22%) (81.16%) (39.07%) (58.89%) (64.01%) (33.00%) 121.56%
Average Days of Receivables
121.44 88.65 75.87 165.52 177.17 68.31 68.19 62.72 64.03 44.57
Earnings Yield
(11.79%) (14.34%) (12.14%) (28.41%) (14.50%) (7.44%) (11.62%) (19.44%) (5.72%) 16.03%
Free Cash Flow Yield
(12.53%) (9.02%) (11.16%) (22.55%) (10.88%) (5.83%) (7.67%) (8.34%) (3.42%) 21.10%
Free Cash Flow per Share
(0.80) (0.49) (0.90) (0.78) (0.81) (0.81) (0.88) (0.51) (0.26) 1.65
Book value per Share
0.02 0.99 0.48 0.33 (0.12) (0.60) (1.58) (2.37) (2.30) (0.57)
Free Cash Flow
(58.71) (41.46) (92.93) (89.93) (135.62) (144.54) (163.20) (97.31) (53.14) 345.45
EV/EBIT
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.41
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Columns are period end dates · fundamentals updated 4 Nov 2026