BioCryst Pharmaceuticals, Inc.

BCRX Healthcare Drug Manufacturers Specialty & Generic

BioCryst Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $874.8 million, up 94.1% from fiscal 2024. In the quarter to June 2026, revenue grew 33.6%, EPS grew 1,450.0%, free cash flow grew 153.2% and total debt rose 15.2%, each against the same quarter a year earlier. Revenue growth for five consecutive years, operating cash flow growth for three.

7.79 0.23 −2.87%
Market cap
$2.1B
P/E
0.0×
Fwd P/E
−3.5×
Dividend yield
—
F-score
7/9
Altman Z
1.83
Beneish M
−2.27
Dividend safety
n/a
Dec '25 Dec '24 Dec '23 Dec '22 Dec '21 Dec '20 Dec '19 Dec '18 Dec '17 Dec '16
P/E ratio
6.24 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Piotroski F-Score
7 3 4 3 5 2 3 2 5 2
P/S ratio
1.87 3.45 3.52 7.86 15.78 69.96 8.17 40.32 18.24 17.79
Altman Z-Score
1.83 (2.55) (3.06) (1.69) (0.52) (3.06) (6.07) (3.47) (2.91) (6.97)
P/FCF ratio
4.74 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Altman Z″-Score (non-manufacturers)
(2.63) (8.82) (8.05) (5.90) (3.73) (9.26) (16.46) (18.03) (10.93) (23.23)
Beneish M-Score
(2.27) (0.91) (3.82) (2.23) 4.12 (4.64) (0.91) (3.57) (3.09) (2.04)
P/Operating CF
5.61 (298.17) (130.82) (89.26) (76.43) (29.30) (38.17) (34.72) (43.67) (80.07)
P/B ratio
0.00 0.00 0.00 0.00 0.00 0.00 10.43 16.91 5.48 297.04
Price to Tangible BV
0.00 0.00 0.00 0.00 0.00 0.00 10.43 16.91 5.48 297.04
EV/Sales
2.11 4.58 4.87 9.01 16.31 68.66 6.45 36.77 14.60 16.62
EV/EBITDA
5.45 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
EV/Operating CF
5.31 (39.68) (16.96) (15.08) (18.03) (9.05) (3.51) (8.20) (8.94) (8.20)
EV/FCF
5.34 (38.84) (16.58) (14.95) (17.73) (9.02) (3.50) (8.17) (8.87) (7.46)
Quick Ratio
1.95 2.49 2.99 4.51 5.21 2.95 1.73 1.59 1.65 1.20
Current Ratio
2.06 2.63 3.31 4.90 5.46 3.06 1.78 1.65 1.68 1.23
Net Debt/EBITDA
0.61 (39.91) (3.98) (2.09) (0.47) 0.13 0.85 0.79 1.65 0.05
Debt/Assets
93.53% 169.39% 162.04% 134.08% 100.86% 83.50% 30.64% 22.24% 14.57% 59.79%
Debt/Equity
(4.04) (1.75) (1.84) (2.50) (5.54) (14.51) 1.40 0.66 0.31 34.05
Asset Turnover
1.74 0.89 0.62 0.48 0.34 0.07 0.30 0.13 0.19 0.25
Operating CF/Net income
1.32 0.59 0.42 0.66 0.77 0.74 0.82 0.91 0.63 0.97
Capex/Depreciation
0.65 0.11 0.25 3.97 (3.08) (0.59) (0.41) (0.21) (0.18) (3.37)
Interest Coverage
4.32 (0.03) (0.96) (1.50) (3.00) (12.05) (8.36) (10.27) (6.70) (7.49)
ROE
(88.68%) 19.08% 60.40% 123.07% 291.59% (1,925.37%) (248.94%) (152.26%) (154.16%) (223.70%)
ROA
52.53% (17.65%) (42.46%) (43.42%) (39.89%) (71.69%) (67.61%) (62.29%) (49.07%) (51.97%)
ROIC
245.61% (4.71%) 0.00% (544.24%) 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Tangible Assets
121.56% (33.00%) (64.01%) (58.89%) (39.07%) (81.16%) (137.22%) (187.47%) (109.45%) (244.55%)
Average Days of Receivables
44.57 64.03 62.72 68.19 68.31 177.17 165.52 75.87 88.65 121.44
Research and Development Expense of Revenue
18.99% 38.75% 65.35% 93.53% 132.85% 690.34% 219.24% 411.02% 265.87% 231.50%
Selling, General and Administrative Expense of Revenue
39.85% 59.09% 64.59% 58.85% 75.60% 381.37% 76.01% 142.90% 55.32% 42.70%
Intangible Assets out of Total Assets
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Share Based Compensation of Revenue
9.72% 14.51% 16.78% 16.51% 22.04% 83.06% 36.28% 45.49% 50.11% 32.21%
Graham Net Nets
(0.14) (0.35) (0.41) (0.15) (0.05) (0.02) 0.07 0.02 0.07 (0.05)
Graham Number
0.00 4.72 7.93 6.89 3.72 1.67 0.00 0.00 0.00 0.00
Earnings Yield
16.03% (5.72%) (19.44%) (11.62%) (7.44%) (14.50%) (28.41%) (12.14%) (14.34%) (11.79%)
Free Cash Flow Yield
21.10% (3.42%) (8.34%) (7.67%) (5.83%) (10.88%) (22.55%) (11.16%) (9.02%) (12.53%)
Revenue per Share
4.17 2.18 1.72 1.46 0.88 0.11 0.42 0.20 0.30 0.36
Operating CF per Share
1.66 (0.25) (0.49) (0.87) (0.79) (0.81) (0.77) (0.90) (0.49) (0.73)
Capex per Share
(0.01) (0.01) (0.01) (0.01) (0.01) 0.00 0.00 0.00 0.00 (0.07)
Free Cash Flow per Share
1.65 (0.26) (0.51) (0.88) (0.81) (0.81) (0.78) (0.90) (0.49) (0.80)
Cash per Share
1.31 1.55 2.03 2.29 2.85 1.81 1.19 1.03 1.39 0.76
Shareholders Equity per Share
(0.57) (2.30) (2.37) (1.58) (0.60) (0.12) 0.33 0.48 0.99 0.02
Interest Debt per Share
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Book value per Share
(0.57) (2.30) (2.37) (1.58) (0.60) (0.12) 0.33 0.48 0.99 0.02
Free Cash Flow
345.45 (53.14) (97.31) (163.20) (144.54) (135.62) (89.93) (92.93) (41.46) (58.71)
Working Capital
208.28 261.58 345.98 410.99 462.42 218.15 72.01 44.88 50.56 12.63
Capital Expenditures
(1.92) (1.12) (2.17) (1.35) (2.38) (0.51) (0.34) (0.37) (0.32) (5.27)
Net Current Asset Value
(228.96) (544.39) (476.52) (328.10) (129.00) (30.18) 27.32 16.75 30.90 (21.28)
EV/EBIT
5.41 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Capex to Sales
0.00 0.00 0.01 0.01 0.02 0.03 0.01 0.02 0.01 0.20
Price to Operating Income
4.80 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Other line items
Depreciation/Fixed assets
(0.33) (1.31) (1.09) (0.04) 0.09 0.12 0.11 0.19 0.18 0.16
Cash ROIC
54.26% (7.86%) (12.59%) (18.79%) (14.49%) (24.10%) (39.14%) (49.46%) (18.23%) (52.66%)
Accounts Receivable Turnover
9.41 6.63 6.16 6.77 8.26 1.16 3.69 3.97 3.38 3.51
Accounts Payable Turnover
1.39 0.75 0.25 0.30 0.31 0.09 0.34 0.12 0.22 0.34
Inventory Turnover
2.83 0.67 0.16 0.30 0.63 0.36 2.26 0.80 2.28 2.18
Average Days of Payables
302.83 346.41 1,701.84 817.72 1,404.06 4,406.61 1,370.27 3,312.72 2,025.40 678.36
Days of Inventory on Hand
103.29 240.59 2,336.37 1,568.28 797.30 1,657.57 161.54 703.14 159.81 79.45
Average Receivables
92.94 68.01 53.77 40.01 19.03 15.40 13.22 5.21 7.44 7.51
Average Payables
13.74 16.27 17.62 21.08 23.26 16.35 10.88 7.05 5.30 6.79
Average Inventory
6.74 18.39 28.11 21.66 11.42 4.34 1.65 1.07 0.50 1.06
Average Assets
502.29 503.69 533.48 569.08 461.43 255.00 161.06 162.55 134.05 106.10
Average Common Equity
(297.54) (465.73) (375.06) (200.79) (63.12) 9.50 43.74 66.50 42.67 24.65

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