BioCryst Pharmaceuticals, Inc.

BCRX Healthcare Drug Manufacturers Specialty & Generic

BioCryst Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $874.8 million, up 94.1% from fiscal 2024. In the quarter to June 2026, revenue grew 33.6%, EPS grew 1,450.0%, free cash flow grew 153.2% and total debt rose 15.2%, each against the same quarter a year earlier. Revenue growth for five consecutive years, operating cash flow growth for three.

7.79 0.23 −2.87%
Market cap
$2.1B
P/E
0.0×
Fwd P/E
−3.5×
Dividend yield
—
F-score
7/9
Altman Z
1.83
Beneish M
−2.27
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
P/E ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 6.24
Piotroski F-Score
2 5 2 3 2 5 3 4 3 7
P/S ratio
17.79 18.24 40.32 8.17 69.96 15.78 7.86 3.52 3.45 1.87
Altman Z-Score
(6.97) (2.91) (3.47) (6.07) (3.06) (0.52) (1.69) (3.06) (2.55) 1.83
P/FCF ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 4.74
Altman Z″-Score (non-manufacturers)
(23.23) (10.93) (18.03) (16.46) (9.26) (3.73) (5.90) (8.05) (8.82) (2.63)
Beneish M-Score
(2.04) (3.09) (3.57) (0.91) (4.64) 4.12 (2.23) (3.82) (0.91) (2.27)
P/Operating CF
(80.07) (43.67) (34.72) (38.17) (29.30) (76.43) (89.26) (130.82) (298.17) 5.61
P/B ratio
297.04 5.48 16.91 10.43 0.00 0.00 0.00 0.00 0.00 0.00
Price to Tangible BV
297.04 5.48 16.91 10.43 0.00 0.00 0.00 0.00 0.00 0.00
EV/Sales
16.62 14.60 36.77 6.45 68.66 16.31 9.01 4.87 4.58 2.11
EV/EBITDA
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.45
EV/Operating CF
(8.20) (8.94) (8.20) (3.51) (9.05) (18.03) (15.08) (16.96) (39.68) 5.31
EV/FCF
(7.46) (8.87) (8.17) (3.50) (9.02) (17.73) (14.95) (16.58) (38.84) 5.34
Quick Ratio
1.20 1.65 1.59 1.73 2.95 5.21 4.51 2.99 2.49 1.95
Current Ratio
1.23 1.68 1.65 1.78 3.06 5.46 4.90 3.31 2.63 2.06
Net Debt/EBITDA
0.05 1.65 0.79 0.85 0.13 (0.47) (2.09) (3.98) (39.91) 0.61
Debt/Assets
59.79% 14.57% 22.24% 30.64% 83.50% 100.86% 134.08% 162.04% 169.39% 93.53%
Debt/Equity
34.05 0.31 0.66 1.40 (14.51) (5.54) (2.50) (1.84) (1.75) (4.04)
Asset Turnover
0.25 0.19 0.13 0.30 0.07 0.34 0.48 0.62 0.89 1.74
Operating CF/Net income
0.97 0.63 0.91 0.82 0.74 0.77 0.66 0.42 0.59 1.32
Capex/Depreciation
(3.37) (0.18) (0.21) (0.41) (0.59) (3.08) 3.97 0.25 0.11 0.65
Interest Coverage
(7.49) (6.70) (10.27) (8.36) (12.05) (3.00) (1.50) (0.96) (0.03) 4.32
ROE
(223.70%) (154.16%) (152.26%) (248.94%) (1,925.37%) 291.59% 123.07% 60.40% 19.08% (88.68%)
ROA
(51.97%) (49.07%) (62.29%) (67.61%) (71.69%) (39.89%) (43.42%) (42.46%) (17.65%) 52.53%
ROIC
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% (544.24%) 0.00% (4.71%) 245.61%
Return on Tangible Assets
(244.55%) (109.45%) (187.47%) (137.22%) (81.16%) (39.07%) (58.89%) (64.01%) (33.00%) 121.56%
Average Days of Receivables
121.44 88.65 75.87 165.52 177.17 68.31 68.19 62.72 64.03 44.57
Research and Development Expense of Revenue
231.50% 265.87% 411.02% 219.24% 690.34% 132.85% 93.53% 65.35% 38.75% 18.99%
Selling, General and Administrative Expense of Revenue
42.70% 55.32% 142.90% 76.01% 381.37% 75.60% 58.85% 64.59% 59.09% 39.85%
Intangible Assets out of Total Assets
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Share Based Compensation of Revenue
32.21% 50.11% 45.49% 36.28% 83.06% 22.04% 16.51% 16.78% 14.51% 9.72%
Graham Net Nets
(0.05) 0.07 0.02 0.07 (0.02) (0.05) (0.15) (0.41) (0.35) (0.14)
Graham Number
0.00 0.00 0.00 0.00 1.67 3.72 6.89 7.93 4.72 0.00
Earnings Yield
(11.79%) (14.34%) (12.14%) (28.41%) (14.50%) (7.44%) (11.62%) (19.44%) (5.72%) 16.03%
Free Cash Flow Yield
(12.53%) (9.02%) (11.16%) (22.55%) (10.88%) (5.83%) (7.67%) (8.34%) (3.42%) 21.10%
Revenue per Share
0.36 0.30 0.20 0.42 0.11 0.88 1.46 1.72 2.18 4.17
Operating CF per Share
(0.73) (0.49) (0.90) (0.77) (0.81) (0.79) (0.87) (0.49) (0.25) 1.66
Capex per Share
(0.07) 0.00 0.00 0.00 0.00 (0.01) (0.01) (0.01) (0.01) (0.01)
Free Cash Flow per Share
(0.80) (0.49) (0.90) (0.78) (0.81) (0.81) (0.88) (0.51) (0.26) 1.65
Cash per Share
0.76 1.39 1.03 1.19 1.81 2.85 2.29 2.03 1.55 1.31
Shareholders Equity per Share
0.02 0.99 0.48 0.33 (0.12) (0.60) (1.58) (2.37) (2.30) (0.57)
Interest Debt per Share
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Book value per Share
0.02 0.99 0.48 0.33 (0.12) (0.60) (1.58) (2.37) (2.30) (0.57)
Free Cash Flow
(58.71) (41.46) (92.93) (89.93) (135.62) (144.54) (163.20) (97.31) (53.14) 345.45
Working Capital
12.63 50.56 44.88 72.01 218.15 462.42 410.99 345.98 261.58 208.28
Capital Expenditures
(5.27) (0.32) (0.37) (0.34) (0.51) (2.38) (1.35) (2.17) (1.12) (1.92)
Net Current Asset Value
(21.28) 30.90 16.75 27.32 (30.18) (129.00) (328.10) (476.52) (544.39) (228.96)
EV/EBIT
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.41
Capex to Sales
0.20 0.01 0.02 0.01 0.03 0.02 0.01 0.01 0.00 0.00
Price to Operating Income
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 4.80
Other line items
Depreciation/Fixed assets
0.16 0.18 0.19 0.11 0.12 0.09 (0.04) (1.09) (1.31) (0.33)
Cash ROIC
(52.66%) (18.23%) (49.46%) (39.14%) (24.10%) (14.49%) (18.79%) (12.59%) (7.86%) 54.26%
Accounts Receivable Turnover
3.51 3.38 3.97 3.69 1.16 8.26 6.77 6.16 6.63 9.41
Accounts Payable Turnover
0.34 0.22 0.12 0.34 0.09 0.31 0.30 0.25 0.75 1.39
Inventory Turnover
2.18 2.28 0.80 2.26 0.36 0.63 0.30 0.16 0.67 2.83
Average Days of Payables
678.36 2,025.40 3,312.72 1,370.27 4,406.61 1,404.06 817.72 1,701.84 346.41 302.83
Days of Inventory on Hand
79.45 159.81 703.14 161.54 1,657.57 797.30 1,568.28 2,336.37 240.59 103.29
Average Receivables
7.51 7.44 5.21 13.22 15.40 19.03 40.01 53.77 68.01 92.94
Average Payables
6.79 5.30 7.05 10.88 16.35 23.26 21.08 17.62 16.27 13.74
Average Inventory
1.06 0.50 1.07 1.65 4.34 11.42 21.66 28.11 18.39 6.74
Average Assets
106.10 134.05 162.55 161.06 255.00 461.43 569.08 533.48 503.69 502.29
Average Common Equity
24.65 42.67 66.50 43.74 9.50 (63.12) (200.79) (375.06) (465.73) (297.54)

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