Avalo Therapeutics, Inc.

AVTX Healthcare Biotechnology

Avalo Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $59,000.00, down 86.6% from fiscal 2024. In the quarter to June 2026, revenue fell 70.1%, EPS grew 56.8% and free cash flow grew 75.7%, each against the same quarter a year earlier.

11.27 0.74 −6.16%
Market cap
$644.1M
P/E
0.0×
Fwd P/E
−5.2×
Dividend yield
—
F-score
2/9
Altman Z
−2.13
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total sells 8.50
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell 1 — — — 1 4 7 2 1 5 2 —
Insider Ownership 0.00%

Capital & Financial Ratios $m

Market Cap 644.10
Revenue 1.25
Net Income (100.33)
Free Cash Flow (68.29)
Net Debt (400.32)
Current Ratio 19.31 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (5.18) (negative: loss-making)
P/S ratio 394.06 (above 10: high)
P/B ratio 1.10
Past 5Y EPS Growth —
This Y EPS Growth 50.07% (at or above 15%: strong)
Next Y EPS Growth (2.13%) (below 0%: weak)
Next Y revenue growth 280.51% (at or above 10%: strong)
Next 5Y EPS Growth 16.97% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 96.75%
10-year low 10-year high
P/B against its own 10 years 17.56%
10-year low 10-year high
EV/Sales against its own 10 years 84.95%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2028 Powerpack
2027 Powerpack
2026 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 7 135 98 400
Receivables 0 1 — —
Inventory — — — —
Other — — — —
8 139 105 408
2023 2024 2025 Q'26
Payables 0 0 0 3
ST’ Debt — — — —
Other — 0 — —
5 7 13 21

Compound Annual Growth %

10y 5y 3y
Sales — (61.19%) (85.16%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 20.30% 27.59% 0.00%

Revenue $m

Mar Jun Sep Dec Year
’26 — — — — —
’25 — — — — 0
’24 — — 0 0 0
’23 0 1 0 1 2
’22 1 1 15 1 18
’21 0 3 1 0 5
’20 3 1 1 1 7
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (18) (20) — — —
’25 (9) (11) (16) (14) (51)
’24 (6) (16) (12) (15) (49)
’23 (10) (11) (7) (3) (31)
’22 (16) (12) 6 (4) (27)
’21 (18) (19) (16) (17) (71)
’20 (6) (9) (12) (14) (41)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (18) (20) — — —
’25 (9) (82) (16) (14) (51)
’24 (6) (16) (12) (15) (49)
’23 (10) (11) (7) (3) (31)
’22 (16) (13) 6 (4) (27)
’21 (18) (19) (16) (17) (71)
’20 (6) (9) (12) (14) (41)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.98) (0.83) — — —
’25 (1.25) (1.92) (2.19) (0.37) (5.84)
’24 (141.00) (14.07) (2.83) 121.45 (4.69)
’23 (202.38) (140.48) (26.19) 258.32 (114.00)
’22 (571.66) (328.57) 80.95 (247.62) (1.05k)
’21 (914.65) (514.49) (485.91) (392.83) (2.37k)
’20 (971.82) (543.07) (485.91) (484.51) (2.46k)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 2,183.04 979.20 6,278.40 8,380.80 4,377.60 4,608.00 581.76 7.92 3.95 3.39

Analyst estimates 2026–2028

Powerpack
High 16,128.00 12,240.00 16,528.32 22,032.00 15,465.60 12,960.00 5,414.40 1,296.00 34.46 20.72
People
People Employees 15 38 64 18 32 44 20 19 23 33
Revenue/emp, $m 0.08 0.73 0.11 0.38 0.21 0.12 0.90 0.10 0.02 0.00
Income, $m
Income, $m Revenue 1 28 7 7 7 5 18 2 0 0
Gross margin, % 100.00 97.71 53.61 108.39 95.52 72.38 80.98 33.26 182.99 100.00
EBT (16) 14 (35) (16) (67) (85) (42) (32) (35) (78)
EBT margin, % (1,428.59) 49.75 (502.58) (236.88) (1,002.79) (1,566.23) (230.62) (1,638.77) (7,939.91) (132,362.71)
Net income (16) 12 (40) (16) (63) (84) (42) (32) (35) (78)
Depreciation 0 1 7 5 2 2 2 6 0 0
Per share, $
Per share, $ Revenue 371.94 4,345.80 576.10 450.03 287.51 154.23 460.48 6.93 0.10 0.00
Earnings (5,344.99) 1,200.48 (3,174.71) (1,071.41) (2,458.13) (2,372.38) (1,054.76) (114.00) (7.94) (5.84)
Cash flow (4,701.00) 1,965.44 (256.40) (1,275.62) (1,739.87) (2,025.49) (682.42) (110.48) (11.08) (3.84)
Capex (11.26) (3.64) (46.26) (17.47) (2.70) (3.23) (2.42) 0.09 0.00 0.00
Free cash flow (4,712.26) 1,961.80 (302.66) (1,293.09) (1,742.58) (2,028.71) (684.85) (110.39) (11.08) (3.84)
Book value 66.77 4,353.06 1,713.75 1,399.71 1,054.16 659.49 (278.44) 26.30 30.06 6.20
Shares, m 0 0 0 0 0 0 0 0 4 13
Valuation, ×
Valuation, × P/E 0.00 7.70 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S 0.00 2.21 16.15 34.49 26.44 31.75 2.61 1.26 26.37 195.21
P/B 38.39 2.20 5.43 11.09 7.21 7.42 0.00 0.33 0.25 2.93
EV/Sales 0.00 2.16 16.82 35.09 24.23 27.90 2.69 3.39 (72.30) 125.56
EV/FCF (0.40) 4.79 (32.01) (12.21) (4.00) (2.12) (1.81) (0.21) 1.84 (1.28)
Cash, $m
Cash, $m Operating cash flow (15) 13 (3) (19) (41) (71) (27) (31) (49) (51)
Capex 0 0 (1) 0 0 0 0 0 — —
Free cash flow (15) 13 (4) (19) (41) (71) (27) (31) (49) (51)
Balance, $m
Balance, $m Working capital 1 0 (4) 6 11 42 (6) 4 132 92
Total debt 2 — 14 1 3 33 13 — — —
Net debt (3) (2) 4 (10) (16) (22) 0 (7) (135) (98)
Shareholders’ equity 0 28 21 21 25 23 (11) 7 133 83
Returns, %
Returns, % ROA (120.11) 32.00 (70.85) (30.22) (159.02) (136.12) (73.35) (116.06) (40.91) (58.58)
ROIC 0.00 34.20 (89.99) (92.94) (526.72) (4,013.58) 0.00 0.00 0.00 0.00
ROE (247.87) 55.38 (164.27) (76.72) (278.79) (354.20) (684.77) 1,747.11 (50.06) (72.43)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Dec 2024

Charts ten years each

Avalo Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
GYRE Gyre Therapeutics, Inc. $678.6M — (loss-making) — (loss-making) −2.12% (below 0%: shrinking) n/m −130.45% (below 0%: shrinking) 92.41% (49.35%) Compare
AURA Aura Biosciences, Inc. $657.5M — (loss-making) — — n/m −56.26% (below 0%: shrinking) 0.00% 0.00% Compare
DSGN Design Therapeutics, Inc. $655.9M — (loss-making) — (loss-making) — n/m −7.00% (below 0%: shrinking) 0.00% 0.00% Compare
PRME Prime Medicine, Inc. $654.8M — (loss-making) — (loss-making) +3.50% (above 0%: growing) n/m +4.40% (above 0%: growing) 100.00% (3,750.87%) Compare
AVTX Avalo Therapeutics, Inc. $644.1M — (loss-making) — (loss-making) −70.14% (below 0%: shrinking) n/m +75.70% (above 0%: growing) 55.73% 0.00%
WVE WAVE Life Sciences Ltd. $628.6M — (loss-making) — (loss-making) −73.88% (below 0%: shrinking) n/m −17.59% (below 0%: shrinking) 100.00% (3,248.33%) Compare
CLYM Climb Bio, Inc. $626.6M — (loss-making) — — n/m +3.73% (above 0%: growing) — 0.00% Compare
NVCT Nuvectis Pharma, Inc. $618.0M — (loss-making) — — n/m −34.57% (below 0%: shrinking) — 0.00% Compare
SLDB Solid Biosciences Inc. $615.5M — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −39.56% (below 0%: shrinking) 0.00% 0.00% Compare
Median of peers $641.7M — — −38.00% — −26.08% 46.21% 0.00%

All 614 Biotechnology stocks →

Avalo Therapeutics, Inc. (AVTX) key facts

  • Concern: Avalo Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $59,000.00, down 86.6% from fiscal 2024.
  • Avalo Therapeutics, Inc. (AVTX) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, AVTX traded at $11.27, a market capitalization of $644.1 million.
  • Return on equity was −72.4% and debt-to-equity 0.00.
  • Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −2.13 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Avalo Therapeutics, Inc. (AVTX) Latest News

stockrow.com/AVTX · Data as of Dec 31, 2024 · For information only; not investment advice. · © 2026 stockrow.com