Friday 16 October 2026
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Alector, Inc.
ALEC Healthcare Biotechnology
Alector, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $21.0 million, down 79.1% from fiscal 2024. In the quarter to June 2026, revenue fell 57.8%, EPS grew 30.0%, free cash flow grew 30.2% and total debt rose 3.27%, each against the same quarter a year earlier.
1.84
0.07
−3.66%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | — | — | — | 13.64 | 9.12 | 14.66 | 6.85 | 3.66 | 1.68 | 0.87 |
Analyst estimates 2026–2028 Powerpack |
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| High | — | — | — | 27.00 | 35.93 | 43.32 | 21.26 | 9.86 | 8.90 | 3.40 | |||||
| People | |||||||||||||||
| People | Employees | — | — | 78 | 121 | 171 | 208 | 273 | 244 | 238 | 103 | ||||
| Revenue/emp, $m | 0.00 | 0.00 | 0.35 | 0.18 | 0.12 | 1.00 | 0.49 | 0.40 | 0.42 | 0.20 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 0 | 4 | 28 | 21 | 21 | 207 | 134 | 97 | 101 | 21 | ||||
| Gross margin, % | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | |||||
| EBT | (15) | (32) | (52) | (105) | (190) | (36) | (130) | (125) | (119) | (143) | |||||
| EBT margin, % | (3,632.21) | (869.61) | (188.78) | (496.65) | (901.64) | (17.54) | (97.33) | (128.97) | (118.26) | (678.36) | |||||
| Net income | (15) | (32) | (52) | (105) | (190) | (36) | (133) | (130) | (119) | (143) | |||||
| Depreciation | 0 | 1 | 1 | 6 | 8 | 10 | 7 | (6) | (6) | 3 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.06 | 0.41 | 2.45 | 0.34 | 0.27 | 2.58 | 1.62 | 1.16 | 1.04 | 0.20 | ||||
| Earnings | (2.11) | (3.55) | (4.62) | (1.71) | (2.45) | (0.45) | (1.62) | (1.56) | (1.23) | (1.39) | |||||
| Cash flow | (1.81) | (1.94) | 11.28 | (1.61) | (2.14) | 3.71 | (0.25) | (2.20) | (2.38) | (1.79) | |||||
| Capex | (0.31) | (0.09) | (0.17) | (0.25) | (0.06) | (0.04) | (0.05) | (0.03) | (0.01) | 0.00 | |||||
| Free cash flow | (2.13) | (2.03) | 11.11 | (1.86) | (2.21) | 3.67 | (0.30) | (2.23) | (2.39) | (1.79) | |||||
| Book value | 0.00 | 2.78 | 10.01 | 3.15 | 3.44 | 3.74 | 2.60 | 1.60 | 1.31 | 0.30 | |||||
| Shares, m | 7 | 9 | 11 | 62 | 78 | 80 | 82 | 84 | 97 | 103 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | 7.67 | 7.67 | 7.67 | 50.13 | 55.76 | 8.02 | 5.62 | 6.89 | 1.82 | 7.64 | |||||
| P/B | 0.00 | 0.00 | 0.00 | 5.46 | 4.40 | 5.52 | 3.50 | 4.99 | 1.44 | 5.24 | |||||
| EV/Sales | (2.82) | (2.82) | (2.82) | 35.75 | 38.60 | 4.70 | 0.61 | 1.65 | (2.12) | (4.07) | |||||
| EV/FCF | (0.62) | (0.62) | (0.62) | (6.62) | (4.74) | 3.29 | (3.31) | (0.86) | 0.92 | 0.47 | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (13) | (18) | 127 | (99) | (167) | 299 | (20) | (184) | (230) | (184) | ||||
| Capex | (2) | (1) | (2) | (15) | (5) | (3) | (4) | (2) | (1) | 0 | |||||
| Free cash flow | (15) | (19) | 126 | (115) | (172) | 295 | (24) | (187) | (231) | (184) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 50 | 206 | 245 | 295 | 353 | 610 | 633 | 388 | 300 | 197 | ||||
| Total debt | — | — | — | 48 | 51 | 48 | 43 | — | 9 | 10 | |||||
| Net debt | (51) | (32) | (290) | (305) | (362) | (688) | (670) | (549) | (404) | (246) | |||||
| Shareholders’ equity | — | 25 | 113 | 195 | 268 | 301 | 214 | 134 | 127 | 31 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (12.80) | (27.52) | (19.19) | (28.86) | (41.80) | (5.58) | (16.64) | (18.50) | (21.84) | (37.54) | ||||
| ROIC | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| ROE | 39.28 | 84.43 | 69.93 | (216.52) | (82.30) | (12.79) | (51.75) | (74.81) | (91.24) | (181.56) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Alector, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| LXEO Lexeo Therapeutics, Inc. | $226.6M | — (loss-making) | — (loss-making) | — | n/m | +35.58% (above 0%: growing) | 0.00% | 0.00% | Compare |
| PLX Protalix BioTherapeutics, Inc. | $217.5M | 11.4× | 10.2× | +27.07% (above 0%: growing) | +2,280.95% (above 0%: growing) | −94.09% (below 0%: shrinking) | 60.99% | 23.48% | Compare |
| CAMP CAMP4 Therapeutics Corporation | $216.5M | — (loss-making) | — (loss-making) | +18.84% (above 0%: growing) | n/m | −23.90% (below 0%: shrinking) | 100.00% | (752.11%) | Compare |
| PYXS Pyxis Oncology, Inc. | $215.3M | — (loss-making) | — (loss-making) | — | n/m | −5.46% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| EVMN Evommune Inc. | $215.2M | — (loss-making) | — (loss-making) | — | n/m | +21.78% (above 0%: growing) | 100.00% | 0.00% | Compare |
| MGNX MacroGenics, Inc. | $214.7M | — (loss-making) | — (loss-making) | +377.97% (above 0%: growing) | n/m | +12.88% (above 0%: growing) | 100.00% | (42.19%) | Compare |
| ALEC Alector, Inc. | $213.3M | — (loss-making) | — (loss-making) | −57.84% (below 0%: shrinking) | n/m | +30.19% (above 0%: growing) | 100.00% | (734.73%) | |
| ZNTL Zentalis Pharmaceuticals, Inc. | $212.1M | — (loss-making) | — (loss-making) | — | n/m | −9.06% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| ADCT ADC Therapeutics SA | $190.2M | — (loss-making) | — (loss-making) | +2.17% (above 0%: growing) | n/m | +50.98% (above 0%: growing) | 87.80% | (132.03%) | Compare |
| Median of peers | $215.2M | — | — | +22.96% | — | +3.71% | 100.00% | 0.00% |
Alector, Inc. (ALEC) key facts
- Concern: Alector, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $21.0 million, down 79.1% from fiscal 2024.
- Concern: Alector, Inc. reported a net loss of $142.9 million, or a loss of $1.39 per share, for fiscal 2025.
- Alector, Inc. (ALEC) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, ALEC traded at $1.84, a market capitalization of $213.3 million.
- Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 14.8× sales.
- Return on equity was −181.6% and debt-to-equity -0.99.
- Its Piotroski F-score is 1 out of 9 and its Altman Z-score is −5.15 (distress zone) for fiscal 2025.