Septerna, Inc. (SEPN) vs Xencor, Inc. (XNCR)

Septerna, Inc. and Xencor, Inc. are both Biotechnology companies. Septerna, Inc. and Xencor, Inc. are of similar size ($1.8B and $1.8B). Septerna, Inc. grew revenue faster over the last twelve months: 13,520.1% against −28.6%. Septerna, Inc. has the higher net margin (−24.5% vs −155.6%) and the higher return on invested capital (−189.0% vs −288.7%). Across the 15 metrics below, Septerna, Inc. leads on 12 and Xencor, Inc. on 3.

Valuation

Metric SEPN XNCR Biotechnology median
P/E n/m n/m 8.50
P/S 16.42 16.58 9.71
P/B 4.20 3.46 2.13
Price to free cash flow 13.81 n/m 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales 12.66 13.38 9.21
Earnings yield (1.50%) (9.46%) (33.15%)
Free cash flow yield 7.24% (12.02%) (25.50%)

Profitability

Metric SEPN XNCR Biotechnology median
Gross margin 100.00% 100.00% 65.16%
Operating margin (44.04%) (205.84%) 0.00%
Net margin (24.51%) (155.59%) 0.00%
Free cash flow margin 118.93% (198.42%) 0.00%
Return on equity (6.34%) (29.07%) (56.36%)
Return on assets (4.94%) (20.36%) (48.04%)
Return on invested capital (189.01%) (288.71%) 0.00%

Growth

Metric SEPN XNCR Biotechnology median
Revenue growth (TTM) 13,520.11% (28.56%) 6.02%
EPS growth (last fiscal year) 84.85% 65.36% 30.26%
Revenue growth, 5-year CAGR — 0.47% 9.41%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric SEPN XNCR Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 4.99 6.39 4.72
Net debt to EBITDA 5.86 2.51 0.96

Dividend

Metric SEPN XNCR Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric SEPN XNCR Biotechnology median
Market cap 1.75b 1.78b 135.18m

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