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Definium Therapeutics, Inc. (DFTX) vs Iovance Biotherapeutics, Inc. (IOVA)

Definium Therapeutics, Inc. and Iovance Biotherapeutics, Inc. are both Biotechnology companies. Definium Therapeutics, Inc. is the larger, with a market value of $4.1B against $3.5B — 1.2× the size. Definium Therapeutics, Inc. has the higher net margin (0.00% vs −58.2%) and the higher return on invested capital (0.00% vs −17.7%). Across the 13 metrics below, Definium Therapeutics, Inc. leads on 7 and Iovance Biotherapeutics, Inc. on 6.

Valuation

Metric DFTX IOVA Biotechnology median
P/E n/m n/m 10.60
P/S n/m 9.49 9.40
P/B 4.01 4.43 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA n/m n/m 0.66
EV/Sales n/m 8.71 9.02
Earnings yield (10.31%) (6.63%) (32.88%)
Free cash flow yield (4.56%) (6.01%) (23.13%)

Profitability

Metric DFTX IOVA Biotechnology median
Gross margin 0.00% 0.00% 68.51%
Operating margin 0.00% (60.79%) 0.00%
Net margin 0.00% (58.19%) 0.00%
Free cash flow margin 0.00% (57.01%) 0.00%
Return on equity (64.09%) (29.11%) (51.96%)
Return on assets (51.35%) (23.26%) (46.06%)
Return on invested capital 0.00% (17.72%) 0.00%

Growth

Metric DFTX IOVA Biotechnology median
Revenue growth (TTM) — 51.34% 6.76%
EPS growth (last fiscal year) (33.77%) 14.84% 29.88%
Revenue growth, 5-year CAGR — — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric DFTX IOVA Biotechnology median
Debt to equity 0.04 0.00 0.00
Current ratio 6.95 5.20 4.97
Net debt to EBITDA 2.21 0.82 1.01

Dividend

Metric DFTX IOVA Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric DFTX IOVA Biotechnology median
Market cap 4.08b 3.51b 161.82m

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