Definium Therapeutics, Inc.

DFTX Healthcare Biotechnology

EPS
−188.0%
Free cash flow
−78.3%
Total debt
−11.5%

Quarter to June 2026, against a year earlier

33.27 2.91 +9.58%
Market cap
$4.1B
P/E
0.0×
Fwd P/E
—
Dividend yield
—
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Sold, $m 7.00
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — — — —
Sell 3 — — 3 — — 5 — — 6 — —
Insider Ownership 0.00%

Capital & Financial Ratios $m

Size
Market Cap 4,080.00
Revenue ttm —
Net income ttm (353.78)
Free cash flow ttm (167.95)
Net debt Q (1,047.41)
Valuation
P/E 0.00
Forward P/E —
Price / sales 0.00
Forward P/S Powerpack
Price / FCF 0.00
Price / book 4.01
Financial health
Current ratio Q 6.95 (at or above 1.5: strong)
Debt / equity Q 0.04 (at or below 0.5: strong)
Interest coverage Q (60.89)
Growth
Revenue growth Q —
Operating income growth Q −83.55% (below 0%: shrinking)
EPS, this year −55.18% (below 0%: weak)
EPS, next year A +35.96% (at or above 15%: strong)
Revenue, next year A —
EPS, past 5 yrs —
EPS, next 5 yrs A +25.36% (at or above 15%: strong)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/B against its own 10 years 54.00%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 100 274 412 1,084
Receivables — — — —
Inventory — — — —
Other — — — —
104 282 419 1,092
2023 2024 2025 Q'26
Payables 4 2 5 7
ST’ Debt — — — —
Other 16 24 41 113
32 39 67 157

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 34.37% 30.10%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (0.71) (1.44) — — —
’25 (0.35) (0.50) (0.78) (0.50) (2.06)
’24 (1.14) (0.08) (0.27) (0.44) (1.54)
’23 (0.65) (0.76) (0.45) (0.59) (2.44)
’22 (0.60) (0.60) (0.56) (0.02) (1.84)
’21 (0.60) (1.35) (0.61) (0.60) (3.45)
’20 (0.52) (0.30) (0.45) (0.58) (1.91)
Fiscal quarters ending in the months shown.

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (43) (53) — — —
’25 (29) (30) (30) (43) (132)
’24 (17) (20) (17) (25) (79)
’23 (13) (14) (17) (21) (64)
’22 (13) (15) (9) (13) (50)
’21 (10) (11) (17) (8) (46)
’20 (5) (6) (6) (7) (24)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (43) (53) — — —
’25 (29) (30) (30) (43) (132)
’24 (17) (20) (17) (25) (79)
’23 (13) (14) (17) (21) (64)
’22 (13) (15) (9) (13) (50)
’21 (10) (11) (17) (8) (46)
’20 (5) (6) (6) (7) (24)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Jun ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — — — — — — — — — — — 29 29 271 +203.9%
Gross margin, % — 0.00 0.00 0.00 0.00 0.00 0.00 — — — 0.00 0.0 pt
EBT 0 (1) (1) (11) (34) (94) (57) (96) (109) (184) (354) +123.3%
EBT margin, % 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.0 pt
Net income 0 0 (1) (11) (34) (93) (57) (96) (109) (184) (354) +123.3%
Per share, $
Per share, $ Revenue 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 n/m
Earnings (0.09) — (2.02) (1.56) (1.91) (3.45) (1.84) (2.44) (1.54) (2.06) (3.43) +41.8%
Cash flow (0.02) (2.11) (1.70) (0.47) (1.33) (1.67) (1.62) (1.64) (1.12) (1.47) (1.52) +64.9%
Capex 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 n/m
Free cash flow (0.02) (2.11) (1.70) (0.47) (1.33) (1.67) (1.62) (1.64) (1.12) (1.47) (1.52) +64.9%
Book value 0.08 12.49 8.29 0.00 4.27 5.54 4.89 2.00 3.43 3.72 8.30 +53.6%
Shares, m 1 0 0 7 18 27 31 39 70 89 99 +61.3%
Valuation, ×
Valuation, × P/E — — — — — — — — — — 0 —
P/S — — — — — — — — — — 0 —
P/B — — — — — — — — — — 0 —
EV/Sales — — — — — — — — — — 0 —
EV/FCF — — — — — — — — — — 0 —
Cash, $m
Cash, $m Operating cash flow 0 (1) (1) (3) (24) (46) (50) (64) (79) (132) (168) +166.0%
Capex 0 (2) (1) 0 — — — — — — 0 +121.2%
Free cash flow 0 (1) (1) (3) (24) (46) (50) (64) (79) (132) (168) +166.0%
Balance, $m
Balance, $m Working capital 0 1 0 2 79 127 128 72 243 353 935 +170.8%
Net debt 0 (1) 0 0 (80) (134) (142) (86) (252) (371) (1,047) +150.4%
Shareholders’ equity 0 3 3 — 76 152 151 78 241 332 919 +147.8%
Returns, %
Returns, % ROA (7.90) (1,306.54) (45.91) (823.70) (80.69) (75.79) (34.01) (65.01) (50.94) (49.52) (51.35) (41.6) pt
ROIC 0.00 0.00 0.00 0.00 0.00 (323.63) (472.44) 0.00 0.00 0.00 0.00 0.0 pt
ROE (8.20) (60.35) (21.94) (455.48) (87.05) (81.78) (37.54) (83.59) (68.01) (64.06) (64.09) (55.9) pt
People
People Employees — — — — — 41 48 57 74 106 — +26.8%
Revenue/emp, $m — — — — — 0.00 0.00 0.00 0.00 0.00 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fundamentals updated 26 Oct 2026

Definium Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
DNTH Dianthus Therapeutics, Inc. $4.6B — (loss-making) — (loss-making) +205.56% (above 0%: growing) n/m −65.91% (below 0%: shrinking) 100.00% (4,832.40%) Compare
ERAS Erasca, Inc. $4.6B — (loss-making) — — n/m −4.67% (below 0%: shrinking) 0.00% 0.00% Compare
LEGN Legend Biotech Corporation Sponsored ADR $4.4B — (loss-making) — (loss-making) +51.90% (above 0%: growing) n/m −26.79% (below 0%: shrinking) 64.54% 14.37% Compare
EWTX Edgewise Therapeutics, Inc. $4.2B 4.9× — — n/m −30.24% (below 0%: shrinking) 0.00% 0.00% Compare
DFTX Definium Therapeutics, Inc. $4.1B — (loss-making) — — n/m −78.31% (below 0%: shrinking) 0.00% 0.00%
RLAY Relay Therapeutics, Inc. $3.7B — (loss-making) — (loss-making) −95.44% (below 0%: shrinking) n/m +2.13% (above 0%: growing) 100.00% 0.00% Compare
ACAD ACADIA Pharmaceuticals Inc. $3.7B 10.0× 33.4× +22.85% (above 0%: growing) −27.86% (below 0%: shrinking) +141.15% (above 0%: growing) 89.75% 20.95% Compare
XENE Xenon Pharmaceuticals Inc. $3.7B — (loss-making) — (loss-making) +100.70% (above 0%: growing) n/m −48.57% (below 0%: shrinking) 100.00% 0.00% Compare
ABCL AbCellera Biologics Inc. $3.6B — (loss-making) — (loss-making) −76.29% (below 0%: shrinking) n/m +151.98% (above 0%: growing) 100.00% (1,550.05%) Compare
Median of peers $4.0B — — +37.38% — −15.73% 94.88% 0.00%

All 621 Biotechnology stocks →

Pay and ownership Proxy statement filed 27 April 2026

Ownership

Directors and executive officers, together 2.40%
Commodore Capital LP 6.80%
Driehaus Capital Management LLC 6.00%
BlackRock,Inc. 5.60%
Deep Track Capital, LP 5.20%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Definium Therapeutics, Inc. (DFTX) Latest News

DFTX metrics, ten years each

stockrow.com/DFTX · Data as of Oct 26, 2026 · For information only; not investment advice. · © 2026 stockrow.com