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ACADIA Pharmaceuticals Inc. (ACAD) vs Definium Therapeutics, Inc. (DFTX)

ACADIA Pharmaceuticals Inc. and Definium Therapeutics, Inc. are both Biotechnology companies. Definium Therapeutics, Inc. is the larger, with a market value of $4.1B against $3.7B — 1.1× the size. Definium Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; ACADIA Pharmaceuticals Inc. trades at 10.0×. ACADIA Pharmaceuticals Inc. has the higher net margin (30.1% vs 0.00%) and the higher return on invested capital (18.6% vs 0.00%). Across the 14 metrics below, ACADIA Pharmaceuticals Inc. leads on 13 and Definium Therapeutics, Inc. on 1.

Valuation

Metric ACAD DFTX Biotechnology median
P/E 9.97 n/m 10.60
P/S 3.05 n/m 9.40
P/B 2.64 4.01 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA 20.09 n/m 0.66
EV/Sales 2.23 n/m 9.02
Earnings yield 10.03% (10.31%) (32.88%)
Free cash flow yield (3.16%) (4.56%) (23.13%)

Profitability

Metric ACAD DFTX Biotechnology median
Gross margin 90.48% 0.00% 68.51%
Operating margin 10.17% 0.00% 0.00%
Net margin 30.13% 0.00% 0.00%
Free cash flow margin 6.82% 0.00% 0.00%
Return on equity 31.43% (64.09%) (51.96%)
Return on assets 23.18% (51.35%) (46.06%)
Return on invested capital 18.60% 0.00% 0.00%

Growth

Metric ACAD DFTX Biotechnology median
Revenue growth (TTM) 14.82% — 6.76%
EPS growth (last fiscal year) 69.12% (33.77%) 29.88%
Revenue growth, 5-year CAGR 19.39% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ACAD DFTX Biotechnology median
Debt to equity 0.00 0.04 0.00
Current ratio 3.82 6.95 4.97
Net debt to EBITDA (7.37) 2.21 1.01

Dividend

Metric ACAD DFTX Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ACAD DFTX Biotechnology median
Market cap 3.66b 4.08b 161.82m

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