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Screener Weekly Summary Pricing

Caris Life Sciences,�Inc. (CAI) vs Protagonist Therapeutics, Inc. (PTGX)

Caris Life Sciences,�Inc. and Protagonist Therapeutics, Inc. are both Biotechnology companies. Caris Life Sciences,�Inc. and Protagonist Therapeutics, Inc. are of similar size ($9.1B and $8.9B). Caris Life Sciences,�Inc. trades at the lower P/E: 85.1× against 117×. Caris Life Sciences,�Inc. grew revenue faster over the last twelve months: 96.4% against 34.8%. Protagonist Therapeutics, Inc. has the higher net margin (29.4% vs 8.15%) and the higher return on invested capital (61.8% vs 50.0%). Across the 20 metrics below, Protagonist Therapeutics, Inc. leads on 11 and Caris Life Sciences,�Inc. on 9.

Valuation

Metric CAI PTGX Biotechnology median
P/E 85.08 116.99 7.88
P/S 9.14 33.37 11.47
P/B 15.29 11.18 2.52
Price to free cash flow 72.98 72.07 21.16
EV/EBITDA 48.03 153.05 0.74
EV/Sales 8.74 30.60 10.73
Earnings yield 1.18% 0.85% (28.84%)
Free cash flow yield 1.37% 1.39% (23.03%)

Profitability

Metric CAI PTGX Biotechnology median
Gross margin 69.66% 100.00% 65.16%
Operating margin 15.49% 20.69% 0.00%
Net margin 8.15% 29.40% 0.00%
Free cash flow margin 12.53% 46.31% 0.00%
Return on equity 15.45% 10.98% (57.72%)
Return on assets 7.39% 10.34% (49.22%)
Return on invested capital 49.95% 61.84% 0.00%

Growth

Metric CAI PTGX Biotechnology median
Revenue growth (TTM) 96.36% 34.81% 5.64%
EPS growth (last fiscal year) 59.45% (148.46%) —
Revenue growth, 5-year CAGR — 9.96% 8.40%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric CAI PTGX Biotechnology median
Debt to equity 0.66 0.00 0.00
Current ratio 5.53 21.71 4.73
Net debt to EBITDA (5.23) 3.49 0.96

Dividend

Metric CAI PTGX Biotechnology median
Dividend yield — — 2.10%
Payout ratio — 0.00 0.00

Size

Metric CAI PTGX Biotechnology median
Market cap 9.12b 8.88b 162.10m

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