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Bicycle Therapeutics PLC Sponsored ADR (BCYC) vs Sionna Therapeutics, Inc. (SION)

Bicycle Therapeutics PLC Sponsored ADR and Sionna Therapeutics, Inc. are both Biotechnology companies. Bicycle Therapeutics PLC Sponsored ADR and Sionna Therapeutics, Inc. are of similar size ($185.0M and $182.9M). Sionna Therapeutics, Inc. has the higher net margin (0.00% vs −311.1%) and the higher return on invested capital (−125.0% vs −64,747.5%). Across the 13 metrics below, Sionna Therapeutics, Inc. leads on 10 and Bicycle Therapeutics PLC Sponsored ADR on 3.

Valuation

Metric BCYC SION Biotechnology median
P/E n/m n/m 8.42
P/S 4.11 n/m 10.01
P/B 0.49 0.70 2.21
Price to free cash flow n/m n/m 21.01
EV/EBITDA 1.16 0.23 0.61
EV/Sales (3.88) n/m 9.41
Earnings yield (75.83%) (53.17%) (31.85%)
Free cash flow yield (82.88%) (41.21%) (24.58%)

Profitability

Metric BCYC SION Biotechnology median
Gross margin 100.00% — 65.16%
Operating margin (343.60%) 0.00% 0.00%
Net margin (311.11%) 0.00% 0.00%
Free cash flow margin (340.29%) 0.00% 0.00%
Return on equity (32.30%) (32.34%) (56.36%)
Return on assets (26.47%) (30.66%) (48.04%)
Return on invested capital (64,747.54%) (125.00%) 0.00%

Growth

Metric BCYC SION Biotechnology median
Revenue growth (TTM) 217.44% — 6.02%
EPS growth (last fiscal year) (8.97%) 88.24% 30.26%
Revenue growth, 5-year CAGR 47.52% — 9.41%
Net income growth, 5-year CAGR 0.00% — 0.00%

Health

Metric BCYC SION Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 12.08 20.05 4.72
Net debt to EBITDA 2.61 2.58 0.96

Dividend

Metric BCYC SION Biotechnology median
Dividend yield — — 0.08%
Payout ratio — — —

Size

Metric BCYC SION Biotechnology median
Market cap 182.88m 184.98m 132.35m

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