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Arrowhead Pharmaceuticals, Inc. (ARWR) vs Rhythm Pharmaceuticals, Inc. (RYTM)

Arrowhead Pharmaceuticals, Inc. and Rhythm Pharmaceuticals, Inc. are both Biotechnology companies. Arrowhead Pharmaceuticals, Inc. is the larger, with a market value of $8.1B against $7.3B — 1.1× the size. Rhythm Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 61.0% against 16.1%. Arrowhead Pharmaceuticals, Inc. has the higher net margin (−47.8% vs −70.6%) and the higher return on invested capital (0.00% vs 0.00%). Across the 16 metrics below, Arrowhead Pharmaceuticals, Inc. leads on 13 and Rhythm Pharmaceuticals, Inc. on 3.

Valuation

Metric ARWR RYTM Biotechnology median
P/E n/m n/m 10.26
P/S 12.34 25.49 9.18
P/B 17.73 81.36 2.05
Price to free cash flow n/m n/m 24.81
EV/EBITDA n/m n/m 0.65
EV/Sales 11.24 24.35 8.98
Earnings yield (3.90%) (2.79%) (34.89%)
Free cash flow yield (0.91%) (1.78%) (24.52%)

Profitability

Metric ARWR RYTM Biotechnology median
Gross margin 100.00% 88.23% 65.16%
Operating margin (33.82%) (66.70%) 0.00%
Net margin (47.79%) (70.63%) 0.00%
Free cash flow margin (11.22%) (29.13%) 0.00%
Return on equity (64.91%) (167.49%) (50.12%)
Return on assets (18.32%) (41.75%) (45.60%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric ARWR RYTM Biotechnology median
Revenue growth (TTM) 16.13% 61.04% 6.26%
EPS growth (last fiscal year) 99.80% 28.34% 29.88%
Revenue growth, 5-year CAGR 56.63% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ARWR RYTM Biotechnology median
Debt to equity 1.85 0.00 0.00
Current ratio 5.90 2.78 4.89
Net debt to EBITDA (5.70) 2.04 1.01

Dividend

Metric ARWR RYTM Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ARWR RYTM Biotechnology median
Market cap 8.12b 7.28b 172.11m

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