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Annexon, Inc. (ANNX) vs Ginkgo Bioworks Holdings, Inc. (DNA)

Annexon, Inc. and Ginkgo Bioworks Holdings, Inc. are both Biotechnology companies. Annexon, Inc. is the larger, with a market value of $794.3M against $679.1M — 1.2× the size. Annexon, Inc. has the higher net margin (0.00% vs −192.0%) and the higher return on invested capital (0.00% vs −155.8%). Across the 14 metrics below, Annexon, Inc. leads on 8 and Ginkgo Bioworks Holdings, Inc. on 6.

Valuation

Metric ANNX DNA Biotechnology median
P/E n/m n/m 11.58
P/S n/m 5.11 9.61
P/B 5.99 1.70 2.26
Price to free cash flow n/m n/m 26.41
EV/EBITDA n/m n/m 0.72
EV/Sales n/m 3.38 9.43
Earnings yield (24.89%) (40.24%) (32.28%)
Free cash flow yield (22.16%) (25.90%) (22.27%)

Profitability

Metric ANNX DNA Biotechnology median
Gross margin 0.00% 69.79% 68.81%
Operating margin 0.00% (204.50%) 0.00%
Net margin 0.00% (191.99%) 0.00%
Free cash flow margin 0.00% (132.29%) 0.00%
Return on equity (130.80%) (52.71%) (50.30%)
Return on assets (82.98%) (23.53%) (45.47%)
Return on invested capital 0.00% (155.79%) 0.00%

Growth

Metric ANNX DNA Biotechnology median
Revenue growth (TTM) — (23.60%) 6.78%
EPS growth (last fiscal year) (32.67%) 46.49% 29.88%
Revenue growth, 5-year CAGR — 17.29% 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ANNX DNA Biotechnology median
Debt to equity 0.35 0.00 0.00
Current ratio 5.79 4.72 4.74
Net debt to EBITDA 1.11 1.63 1.01

Dividend

Metric ANNX DNA Biotechnology median
Dividend yield — — 0.39%
Payout ratio — — —

Size

Metric ANNX DNA Biotechnology median
Market cap 794.34m 679.14m 168.63m

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