Annexon, Inc. (ANNX) vs Rigel Pharmaceuticals, Inc. (RIGL)

Annexon, Inc. and Rigel Pharmaceuticals, Inc. are both Biotechnology companies. Annexon, Inc. and Rigel Pharmaceuticals, Inc. are of similar size ($838.3M and $794.3M). Annexon, Inc. has negative trailing earnings, so its P/E is not meaningful; Rigel Pharmaceuticals, Inc. trades at 2.6×. Rigel Pharmaceuticals, Inc. has the higher net margin (106.6% vs 0.00%) and the higher return on invested capital (13.7% vs 0.00%). Across the 14 metrics below, Rigel Pharmaceuticals, Inc. leads on 13 and Annexon, Inc. on 1.

Valuation

Metric ANNX RIGL Biotechnology median
P/E n/m 2.64 11.58
P/S n/m 2.88 9.61
P/B 5.99 1.87 2.26
Price to free cash flow n/m 42.58 26.41
EV/EBITDA n/m 9.44 0.72
EV/Sales n/m 2.59 9.43
Earnings yield (24.89%) 37.87% (32.28%)
Free cash flow yield (22.16%) 2.35% (22.27%)

Profitability

Metric ANNX RIGL Biotechnology median
Gross margin 0.00% 89.64% 68.81%
Operating margin 0.00% 26.28% 0.00%
Net margin 0.00% 106.59% 0.00%
Free cash flow margin 0.00% 6.72% 0.00%
Return on equity (130.80%) 109.18% (50.30%)
Return on assets (82.98%) 80.16% (45.47%)
Return on invested capital 0.00% 13.69% 0.00%

Growth

Metric ANNX RIGL Biotechnology median
Revenue growth (TTM) — 2.18% 6.78%
EPS growth (last fiscal year) (32.67%) 1,867.68% 29.88%
Revenue growth, 5-year CAGR — 22.06% 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ANNX RIGL Biotechnology median
Debt to equity 0.35 0.00 0.00
Current ratio 5.79 2.39 4.74
Net debt to EBITDA 1.11 (1.05) 1.01

Dividend

Metric ANNX RIGL Biotechnology median
Dividend yield — — 0.39%
Payout ratio — — —

Size

Metric ANNX RIGL Biotechnology median
Market cap 794.34m 838.31m 168.63m

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