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Alumis Inc. (ALMS) vs MeiraGTx Holdings PLC (MGTX)

Alumis Inc. and MeiraGTx Holdings PLC are both Biotechnology companies. Alumis Inc. and MeiraGTx Holdings PLC are of similar size ($817.3M and $780.9M). Alumis Inc. has negative trailing earnings, so its P/E is not meaningful; MeiraGTx Holdings PLC trades at 11.8×. MeiraGTx Holdings PLC has the higher net margin (19.9% vs −5,933.5%) and the higher return on invested capital (66.6% vs 0.00%). Across the 16 metrics below, MeiraGTx Holdings PLC leads on 11 and Alumis Inc. on 5.

Valuation

Metric ALMS MGTX Biotechnology median
P/E n/m 11.83 10.60
P/S 103.91 2.07 9.40
P/B 1.70 3.81 2.13
Price to free cash flow n/m 81.19 25.18
EV/EBITDA n/m 3.94 0.66
EV/Sales 36.01 1.96 9.02
Earnings yield (63.00%) 8.45% (32.88%)
Free cash flow yield (45.77%) 1.23% (23.13%)

Profitability

Metric ALMS MGTX Biotechnology median
Gross margin 100.00% 97.95% 68.51%
Operating margin (6,204.39%) 46.30% 0.00%
Net margin (5,933.45%) 19.87% 0.00%
Free cash flow margin (4,755.33%) 2.55% 0.00%
Return on equity (93.65%) 72.22% (51.96%)
Return on assets (74.94%) 26.54% (46.06%)
Return on invested capital 0.00% 66.60% 0.00%

Growth

Metric ALMS MGTX Biotechnology median
Revenue growth (TTM) — 948.35% 6.76%
EPS growth (last fiscal year) 72.45% 33.02% 29.88%
Revenue growth, 5-year CAGR — 39.22% 9.75%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric ALMS MGTX Biotechnology median
Debt to equity 0.00 0.46 0.00
Current ratio 6.74 3.76 4.97
Net debt to EBITDA 0.69 0.18 1.01

Dividend

Metric ALMS MGTX Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ALMS MGTX Biotechnology median
Market cap 780.94m 817.32m 161.82m

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