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Alumis Inc. (ALMS) vs Annexon, Inc. (ANNX)

Alumis Inc. and Annexon, Inc. are both Biotechnology companies. Alumis Inc. and Annexon, Inc. are of similar size ($780.9M and $759.3M). Annexon, Inc. has the higher net margin (0.00% vs −5,933.5%) and the higher return on invested capital (0.00% vs 0.00%). Across the 12 metrics below, Alumis Inc. leads on 7 and Annexon, Inc. on 5.

Valuation

Metric ALMS ANNX Biotechnology median
P/E n/m n/m 10.60
P/S 103.91 n/m 9.40
P/B 1.70 4.55 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA n/m n/m 0.66
EV/Sales 36.01 n/m 9.02
Earnings yield (63.00%) (27.55%) (32.88%)
Free cash flow yield (45.77%) (22.83%) (23.13%)

Profitability

Metric ALMS ANNX Biotechnology median
Gross margin 100.00% 0.00% 68.51%
Operating margin (6,204.39%) 0.00% 0.00%
Net margin (5,933.45%) 0.00% 0.00%
Free cash flow margin (4,755.33%) 0.00% 0.00%
Return on equity (93.65%) (105.26%) (51.96%)
Return on assets (74.94%) (79.38%) (46.06%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric ALMS ANNX Biotechnology median
Revenue growth (TTM) — — 6.76%
EPS growth (last fiscal year) 72.45% (32.67%) 29.88%
Revenue growth, 5-year CAGR — — 9.75%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric ALMS ANNX Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 6.74 5.53 4.97
Net debt to EBITDA 0.69 1.11 1.01

Dividend

Metric ALMS ANNX Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ALMS ANNX Biotechnology median
Market cap 780.94m 759.27m 161.82m

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