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Agios Pharmaceuticals, Inc. (AGIO) vs Mineralys Therapeutics, Inc. (MLYS)

Agios Pharmaceuticals, Inc. and Mineralys Therapeutics, Inc. are both Biotechnology companies. Agios Pharmaceuticals, Inc. and Mineralys Therapeutics, Inc. are of similar size ($1.9B and $1.9B). Mineralys Therapeutics, Inc. has the higher net margin (0.00% vs −418.2%) and the higher return on invested capital (0.00% vs −70.2%). Across the 13 metrics below, Mineralys Therapeutics, Inc. leads on 8 and Agios Pharmaceuticals, Inc. on 5.

Valuation

Metric AGIO MLYS Biotechnology median
P/E n/m n/m 8.50
P/S 18.95 n/m 9.71
P/B 1.82 3.12 2.13
Price to free cash flow n/m n/m 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales 12.67 n/m 9.21
Earnings yield (22.38%) (20.89%) (33.15%)
Free cash flow yield (19.60%) (8.07%) (25.50%)

Profitability

Metric AGIO MLYS Biotechnology median
Gross margin 91.99% — 65.16%
Operating margin (466.78%) 0.00% 0.00%
Net margin (418.24%) 0.00% 0.00%
Free cash flow margin (371.43%) 0.00% 0.00%
Return on equity (34.34%) (80.88%) (56.36%)
Return on assets (31.89%) (69.67%) (48.04%)
Return on invested capital (70.24%) 0.00% 0.00%

Growth

Metric AGIO MLYS Biotechnology median
Revenue growth (TTM) 140.58% — 6.02%
EPS growth (last fiscal year) (161.17%) 37.43% 30.26%
Revenue growth, 5-year CAGR (14.45%) — 9.41%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric AGIO MLYS Biotechnology median
Debt to equity 0.00 0.18 0.00
Current ratio 10.22 34.46 4.72
Net debt to EBITDA 1.80 3.85 0.96

Dividend

Metric AGIO MLYS Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric AGIO MLYS Biotechnology median
Market cap 1.93b 1.91b 135.18m

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