Agios Pharmaceuticals, Inc. (AGIO) vs Palvella Therapeutics, Inc. (PVLA)

Agios Pharmaceuticals, Inc. and Palvella Therapeutics, Inc. are both Biotechnology companies. Agios Pharmaceuticals, Inc. and Palvella Therapeutics, Inc. are of similar size ($1.9B and $1.8B). Palvella Therapeutics, Inc. grew revenue faster over the last twelve months: 146.7% against 140.6%. Palvella Therapeutics, Inc. has the higher net margin (0.00% vs −418.2%) and the higher return on invested capital (0.00% vs −70.2%). Across the 17 metrics below, Palvella Therapeutics, Inc. leads on 12 and Agios Pharmaceuticals, Inc. on 5.

Valuation

Metric AGIO PVLA Biotechnology median
P/E n/m n/m 8.50
P/S 18.95 41.55 9.71
P/B 1.82 7.96 2.13
Price to free cash flow n/m n/m 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales 12.67 35.55 9.21
Earnings yield (22.38%) (4.01%) (33.15%)
Free cash flow yield (19.60%) (1.86%) (25.50%)

Profitability

Metric AGIO PVLA Biotechnology median
Gross margin 91.99% 100.00% 65.16%
Operating margin (466.78%) 0.00% 0.00%
Net margin (418.24%) 0.00% 0.00%
Free cash flow margin (371.43%) 0.00% 0.00%
Return on equity (34.34%) (46.63%) (56.36%)
Return on assets (31.89%) (37.70%) (48.04%)
Return on invested capital (70.24%) 0.00% 0.00%

Growth

Metric AGIO PVLA Biotechnology median
Revenue growth (TTM) 140.58% 146.67% 6.02%
EPS growth (last fiscal year) (161.17%) 52.62% 30.26%
Revenue growth, 5-year CAGR (14.45%) 8.03% 9.41%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric AGIO PVLA Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 10.22 21.18 4.72
Net debt to EBITDA 1.80 1.50 0.96

Dividend

Metric AGIO PVLA Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric AGIO PVLA Biotechnology median
Market cap 1.93b 1.83b 135.18m

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