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Agenus Inc. (AGEN) vs Prelude Therapeutics Incorporated (PRLD)

Agenus Inc. and Prelude Therapeutics Incorporated are both Biotechnology companies. Agenus Inc. and Prelude Therapeutics Incorporated are of similar size ($290.8M and $283.7M). Prelude Therapeutics Incorporated has negative trailing earnings, so its P/E is not meaningful; Agenus Inc. trades at 10.7×. Agenus Inc. has the higher net margin (22.0% vs −269.8%) and the higher return on invested capital (0.00% vs 0.00%). Across the 13 metrics below, Agenus Inc. leads on 11 and Prelude Therapeutics Incorporated on 2.

Valuation

Metric AGEN PRLD Biotechnology median
P/E 10.70 n/m 10.60
P/S 3.33 15.80 9.40
P/B n/m 2.65 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA 7.99 n/m 0.66
EV/Sales 3.24 9.03 9.02
Earnings yield 9.35% (20.28%) (32.88%)
Free cash flow yield (23.17%) (9.41%) (23.13%)

Profitability

Metric AGEN PRLD Biotechnology median
Gross margin 100.00% 100.00% 68.51%
Operating margin 38.94% (300.56%) 0.00%
Net margin 21.99% (269.75%) 0.00%
Free cash flow margin (77.54%) (148.30%) 0.00%
Return on equity (14.99%) (57.73%) (51.96%)
Return on assets 12.29% (39.76%) (46.06%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric AGEN PRLD Biotechnology median
Revenue growth (TTM) 25.38% — 6.76%
EPS growth (last fiscal year) 100.00% 23.21% 29.88%
Revenue growth, 5-year CAGR 5.31% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric AGEN PRLD Biotechnology median
Debt to equity (0.22) 0.00 0.00
Current ratio 0.73 4.07 4.97
Net debt to EBITDA (4.10) 1.00 1.01

Dividend

Metric AGEN PRLD Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric AGEN PRLD Biotechnology median
Market cap 290.84m 283.70m 161.82m

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