Xeris Biopharma Holdings, Inc.

XERS Healthcare Drug Manufacturers Specialty & Generic

Xeris Biopharma Holdings, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $291.8 million, up 43.7% from fiscal 2024.

Revenue
+44.2%
EPS
+1,479.0%
Free cash flow
+93.2%
Total debt
−13.6%

Quarter to September 2026, against a year earlier

15.16 2.08 +15.90%
Market cap
$2.4B
P/E
0.0×
Fwd P/E
−143×
Dividend yield
—
F-score
8/9
Altman Z
0.98
Beneish M
−2.58
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
P/E ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2,065.79
Piotroski F-Score
— — 3 1 5 5 4 5 4 8
Altman Z-Score
— — 0.81 (5.01) (2.63) (2.29) (1.96) (1.80) (1.53) 0.98
P/S ratio
0.00 0.00 84.52 67.63 10.27 4.67 1.38 1.91 2.45 4.32
Altman Z″-Score (non-manufacturers)
12.69 5.84 1.06 (11.13) (5.04) (5.62) (4.53) (5.93) (6.20) (2.99)
P/FCF ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 45.09
Beneish M-Score
— 4.77 (2.83) 60.79 1.89 139.26 (1.67) (2.38) (2.72) (2.58)
P/Operating CF
(5.62) (5.62) (11.17) (6.22) (19.30) (8.00) (9.42) 41.83 251.93 62.83
P/B ratio
0.00 0.00 2.72 12.75 6.21 2.43 3.36 0.00 0.00 92.00
EV/Sales
0.00 0.00 51.19 62.39 8.13 4.44 1.98 2.64 3.24 4.73
EV/EBITDA
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 33.70
EV/FCF
(0.35) (0.35) (2.15) (1.61) (2.05) (2.28) (2.11) (8.79) (17.39) 49.43
Current Ratio
13.13 9.06 11.59 3.20 5.40 1.80 2.54 1.64 1.67 2.19
Net Debt/EBITDA
2.46 1.59 1.38 0.14 0.58 0.13 (0.98) (4.14) (8.91) 2.67
Debt/Equity
0.00 0.00 0.42 4.04 2.58 0.92 4.18 (28.15) (7.84) 16.10
ROE
29.43% 59.16% (683.66%) (279.56%) (378.20%) (190.28%) (134.83%) (324.20%) 301.32% (6.96%)
ROA
(33.64%) (67.63%) (72.81%) (109.67%) (67.98%) (52.95%) (29.18%) (18.66%) (16.99%) 0.16%
ROIC
0.00% 0.00% 0.00% 0.00% 0.00% (89.00%) (45.78%) (24.63%) (16.07%) 12.65%
Return on Tangible Assets
(42.67%) (66.42%) (54.74%) (184.68%) (69.73%) (174.86%) (79.74%) (92.86%) (75.34%) 0.41%
Average Days of Receivables
34.29 281.26 432.19 629.30 122.80 128.48 102.07 87.28 72.64 63.85
Earnings Yield
(9.55%) (9.55%) (60.28%) (68.09%) (46.34%) (51.88%) (62.50%) (19.82%) (11.21%) 0.05%
Free Cash Flow Yield
(76.34%) (76.34%) (28.22%) (57.29%) (38.58%) (41.73%) (68.08%) (15.77%) (7.61%) 2.22%
Free Cash Flow per Share
(8.75) (12.51) (4.80) (4.04) (1.90) (1.22) (0.76) (0.36) (0.26) 0.17
Book value per Share
16.81 19.75 6.26 0.55 0.79 1.21 0.33 (0.05) (0.20) 0.09
Free Cash Flow
(16.12) (25.36) (57.79) (105.45) (80.93) (96.62) (103.41) (49.29) (37.85) 27.93
EV/EBIT
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 55.45
Other line items

Show all line items

Columns are period end dates · fundamentals updated 5 Nov 2026