Vertex Pharmaceuticals Incorporated

VRTX Healthcare Biotechnology

Vertex Pharmaceuticals Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $12.0 billion, up 8.90% from fiscal 2024. In the quarter to June 2026, revenue grew 12.5%, EPS grew 7.96% and free cash flow grew 9.25%, each against the same quarter a year earlier. Member of the S&P 500 and Nasdaq 100; revenue growth for ten consecutive years.

499.39 9.36 −1.84%
Market cap
$129.0B
P/E
28.8×
Fwd P/E
25.5×
Dividend yield
—
F-score
8/9
Altman Z
12.06
Beneish M
−2.17
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
P/E ratio
0.00 142.91 20.11 47.91 22.68 24.13 22.04 29.27 0.00 29.31
Piotroski F-Score
5 8 5 6 8 6 7 3 3 8
P/S ratio
10.77 15.29 13.83 13.50 9.89 7.47 8.20 10.73 9.42 9.66
Altman Z-Score
5.37 14.30 14.64 16.27 14.09 12.43 12.94 14.39 11.55 12.06
P/FCF ratio
102.06 51.04 35.87 37.62 20.51 23.50 18.66 31.73 0.00 36.30
Altman Z″-Score (non-manufacturers)
(2.77) 0.36 4.55 5.85 8.34 8.97 10.01 9.23 5.89 7.50
Beneish M-Score
(2.69) (3.32) 1.61 (2.09) (2.36) (2.34) (2.42) (2.18) (2.23) (2.17)
P/Operating CF
126.62 167.26 133.95 126.03 124.92 56.88 67.92 451.37 177.65 232.78
P/B ratio
13.69 18.63 9.50 9.24 7.07 5.60 5.27 6.02 6.33 6.21
EV/Sales
10.38 14.81 13.08 12.79 8.96 6.58 7.08 9.66 8.91 9.14
EV/EBITDA
247.62 199.57 56.32 40.81 18.74 17.15 14.18 23.76 0.00 25.03
EV/FCF
98.38 49.43 33.92 35.63 18.57 20.71 16.10 28.57 (100.36) 34.36
Current Ratio
2.31 3.28 3.43 3.61 4.33 4.46 4.83 3.99 2.69 2.90
Net Debt/EBITDA
(9.27) (8.15) (3.66) (2.51) (2.06) (2.41) (2.32) (2.70) 233.58 (1.51)
Debt/Equity
0.61 0.29 0.13 0.09 0.06 0.05 0.03 0.02 0.01 0.00
ROE
(9.22%) 15.59% 64.74% 22.37% 36.71% 24.93% 27.67% 22.99% (3.15%) 22.54%
ROA
(4.15%) 8.18% 42.83% 16.16% 27.02% 18.60% 21.04% 17.71% (2.37%) 16.41%
ROIC
0.92% 14.33% 21.48% 26.58% 69.55% 56.37% 75.52% 35.54% (1.40%) 21.63%
Return on Tangible Assets
(6.45%) 10.01% 59.32% 27.80% 37.59% 27.51% 28.64% 30.79% (7.38%) 44.62%
Average Days of Receivables
42.96 41.26 49.07 55.55 52.08 54.78 58.94 57.82 53.31 62.43
Earnings Yield
(0.63%) 0.70% 4.97% 2.09% 4.41% 4.14% 4.54% 3.42% (0.51%) 3.41%
Free Cash Flow Yield
0.98% 1.96% 2.79% 2.66% 4.88% 4.26% 5.36% 3.15% (0.94%) 2.76%
Free Cash Flow per Share
0.73 3.00 4.62 5.82 11.52 9.35 15.33 12.72 (3.79) 12.49
Book value per Share
5.47 8.21 17.44 23.71 33.44 39.19 54.33 68.22 63.63 73.00
Free Cash Flow
179.54 745.52 1,174.84 1,493.90 2,993.70 2,408.50 3,925.20 3,278.90 (978.00) 3,193.80
EV/EBIT
1,777.69 298.99 62.74 44.45 19.46 17.93 14.67 24.88 0.00 26.29
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