Upstream Bio, Inc.

UPB Healthcare Biotechnology

Upstream Bio, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $2.9 million, up 20.4% from fiscal 2024. In the quarter to June 2026, revenue fell 17.5%, EPS grew 1.35% and free cash flow grew 9.33%, each against the same quarter a year earlier.

2.76 0.61 −18.10%
Market cap
$184.6M
P/E
0.0×
Fwd P/E
−2.4×
Dividend yield
—
F-score
2/9
Altman Z
60.99
Beneish M
−2.81
Dividend safety
n/a
Older periods Sep '25 Dec '25 Mar '26 Jun '26
P/E ratio

+8 more quarters

2.56 0.00 0.00 0.00
P/S ratio
362.43 512.30 147.20 119.57
P/FCF ratio
0.00 0.00 0.00 0.00
P/Operating CF
(45.61) (47.73) (10.22) (10.60)
P/B ratio
2.68 4.30 1.61 1.39
EV/Sales
229.37 392.64 58.52 36.83
EV/EBITDA
0.00 0.00 0.00 0.00
EV/FCF
(5.22) (8.39) (1.39) (0.85)
Current Ratio
32.67 26.15 23.14 27.99
Net Debt/EBITDA
9.82 7.63 6.65 6.17
Debt/Equity
0.00 0.00 0.00 0.00
Earnings Yield
38.99% (9.83%) (32.33%) (41.91%)
Free Cash Flow Yield
(12.11%) (9.14%) (28.69%) (36.20%)
Free Cash Flow per Share
(0.41) (0.57) (0.88) (0.65)
Book value per Share
7.02 6.31 5.60 4.97
Free Cash Flow
(22.30) (30.68) (47.85) (35.62)
EV/EBIT
0.00 0.00 0.00 0.00
Other line items

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Columns are period end dates