Spero Therapeutics, Inc. SPRO

Healthcare — Biotechnology

Dividend Champion (3y)

Growth Flags show if company had growth for consecutive years

Overview Business Profile Analyst Commentary Income Statement Balance Sheet Cash Flow Metrics & Ratios 10-Q 10-K

Quarterly (Descending) Quarterly (Ascending) Annual (Descending) Annual (Ascending) TTM (Descending) TTM (Ascending)

Financial statements are limited to most recent four years or quarters for non-powerpack users

Ten years worth of data (where available), most important trends and XLS exports are available for our Powerpack users.

	Dec '16	Dec '17	Dec '18	Dec '19	Dec '20	Dec '21	Dec '22	Dec '23	Dec '24	Dec '25
P/E ratio	0.00	0.00	0.00	0.00	‡‡‡	‡‡‡	‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡‡‡
P/S ratio	0.00	15.87	24.81	9.63	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
P/FCF ratio	0.00	0.00	0.00	0.00	‡‡‡	‡‡‡	‡‡‡	‡‡‡	‡‡‡	‡‡‡
P/Operating CF	(0.37)	(2.47)	(7.28)	(10.06)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
P/B ratio	0.00	0.37	0.85	2.34	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Price to Tangible BV	0.00	0.37	0.85	2.34	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
EV/Sales	0.00	(28.24)	(4.29)	5.41	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
EV/EBITDA	0.61	1.35	0.40	0.00	‡‡‡	‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡‡‡
EV/Operating CF	0.61	1.43	0.43	(1.96)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
EV/FCF	0.61	1.39	0.40	(1.95)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Quick Ratio	1.54	11.06	9.48	3.40	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Current Ratio	1.72	11.29	10.08	3.58	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Net Debt/EBITDA	0.31	2.11	2.72	1.22	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Debt/Assets	0.00%	0.00%	0.00%	5.23%	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡	‡‡‡
Debt/Equity	0.00	0.00	0.00	0.07	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡	‡‡‡
Asset Turnover	0.05	0.04	0.04	0.15	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Operating CF/Net income	0.97	0.85	0.95	0.82	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Capex/Depreciation	(2.97)	(0.07)	(5.96)	(0.42)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡	‡‡‡	—
Depreciation/Fixed assets	0.19	0.31	0.14	0.33	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	—
Interest Coverage	0.00	0.00	0.00	0.00	‡‡‡	‡‡‡	‡‡‡	‡‡‡	‡‡‡	‡‡‡
ROE	(169.30%)	(258.18%)	(41.49%)	(63.99%)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
ROA	(434.62%)	(85.96%)	(37.45%)	(51.83%)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
ROIC	0.00%	0.00%	(6,493.63%)	0.00%	‡‡‡‡‡	‡‡‡	‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡‡‡
Cash ROIC	(182.65%)	(23.38%)	(18.38%)	(32.25%)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Return on Tangible Assets	(463.71%)	(54.19%)	(36.29%)	(85.78%)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Accounts Receivable Turnover	0.21	1.22	1.87	3.69	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡	‡‡‡‡‡
Accounts Payable Turnover	0.00	0.00	0.00	0.00	‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡	‡‡‡
Inventory Turnover	—	—	—	—	—	‡‡‡	‡‡‡	—	—	—
Average Days of Receivables	331.22	542.80	119.46	171.89	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Average Days of Payables	0.00	0.00	0.00	0.00	‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡	‡‡‡
Days of Inventory on Hand	—	—	—	—	—	‡‡‡	‡‡‡	—	—	—
Research and Development Expense of Revenue	7,860.60%	1,660.89%	854.39%	362.46%	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Selling, General and Administrative Expense of Revenue	2,156.12%	547.75%	324.94%	85.90%	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Intangible Assets out of Total Assets	0.00	0.00	0.00	0.00	‡‡‡	‡‡‡	‡‡‡	‡‡‡	‡‡‡	‡‡‡
Share Based Compensation of Revenue	53.73%	72.11%	69.31%	20.81%	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Graham Net Nets	5.11	2.66	1.13	0.37	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡	‡‡‡‡‡
Graham Number	0.00	0.00	0.00	0.00	‡‡‡	‡‡‡	‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡‡‡
Earnings Yield	(313.22%)	(309.80%)	(42.76%)	(34.30%)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Free Cash Flow Yield	(922.37%)	(128.00%)	(43.03%)	(28.81%)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Revenue per Share	1.07	0.77	0.25	1.00	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Operating CF per Share	(92.76)	(15.12)	(2.48)	(2.75)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Capex per Share	(2.66)	(0.01)	(0.15)	(0.02)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡	‡‡‡	‡‡‡
Free Cash Flow per Share	(95.42)	(15.13)	(2.63)	(2.77)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Cash per Share	33.04	33.74	7.21	4.52	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Shareholders Equity per Share	20.37	32.84	7.24	4.11	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Interest Debt per Share	0.00	0.00	0.00	0.00	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡	‡‡‡
Book value per Share	20.37	32.84	7.24	4.11	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Free Cash Flow	(29.79)	(39.14)	(42.06)	(50.33)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Working Capital	4.95	83.90	111.90	68.75	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Capital Expenditures	(0.83)	(0.03)	(2.44)	(0.31)	‡‡‡‡‡	‡‡‡‡‡	—	—	—	—
Net Current Asset Value	4.46	83.54	111.07	63.89	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Average Receivables	1.62	1.62	2.12	4.92	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Average Payables	2.30	2.30	3.54	3.88	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Average Assets	6.89	53.63	111.24	117.55	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Average Common Equity	17.68	17.85	100.41	95.21	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
EV/EBIT	0.60	1.34	0.40	0.00	‡‡‡	‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡‡‡
Capex to Sales	2.48	0.01	0.61	0.02	‡‡‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡	‡‡‡	‡‡‡
Net Profit Margin	(8,933.73%)	(2,329.31%)	(1,050.48%)	(335.73%)	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡	‡‡‡‡‡
Price to Operating Income	0.00	0.00	0.00	0.00	‡‡‡	‡‡‡	‡‡‡	‡‡‡‡‡	‡‡‡	‡‡‡‡‡

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