Skye Bioscience, Inc. SKYE

1.67 (0.03) (1.76%) as of 25 Sep
Market cap
$7.5M
P/E
0.0×

Insider Decisions

Total sells 0.89
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — — 2 4
Insider Ownership 42.96%

Capital & Financial Ratios

Market Cap 7.53
Revenue 0.30
Net Income (50.49)
Free Cash Flow (38.27)
Net Debt (10.06)
Current Ratio 0.95
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 27.76
P/B ratio 0.00
Past 5Y EPS Growth 42.99%
This Y EPS Growth 47.52%
Next Y EPS Growth (13.82%)
Next 5Y EPS Growth 1.68%
in millions of $

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 10 68 26 10
Receivables — — — —
Inventory — — — —
Other 1 2 1 0
12 71 27 11
2023 2024 2025 Q'26
Payables 1 1 2 4
ST’ Debt 4 — — —
Other 7 2 5 7
14 4 8 12
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — —
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 45.50% 113.56% 0.00%

Revenue

Year
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (9) (7) — — —
’25 (9) (11) (13) (10) (43)
’24 (5) (7) (5) (8) (25)
’23 (4) (2) (4) (4) (14)
’22 (3) (3) (2) (5) (13)
’21 (1) (2) (1) (2) (6)
’20 (1) (1) (2) (2) (6)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (9) (7) — — —
’25 (9) (11) (13) (10) (43)
’24 (4) (7) (7) (8) (25)
’23 1 (2) (4) (4) (8)
’22 (3) (3) (2) (5) (13)
’21 (1) (2) (2) (2) (7)
’20 (1) (1) (2) (2) (6)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (2.56) (2.16) — — —
’25 (2.24) (3.52) (2.56) (2.88) (11.28)
’24 (1.44) (1.60) (0.80) (1.92) (5.84)
’23 (10.97) (6.41) (25.36) (0.29) (42.96)
’22 (12.28) (13.79) (12.61) (40.00) (80.00)
’21 (12.83) (10.70) (8.81) (9.59) (40.00)
’20 (20.00) (15.52) (10.08) (5.61) (60.00)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

3
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
600.00 200.00 100.00 210.00 50.00 78.00 22.00 11.52 18.00 5.47

Analyst estimates 2026–2028

Powerpack
Low Price
3,600.00 1,000.00 1,200.00 2,340.00 400.00 518.00 134.00 112.00 155.28 46.00
High Price
2 3 3 4 6 9 11 7 16 12
Employees
0 0 0 0 0 0 0 0 0 0
Revenue/Emp
— — — — — — — — — —
Revenue
— — — — — — — — — —
Gross Margin
(3) (3) (19) 1 (7) (9) (19) (38) (27) (56)
EBT
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
EBT Margin
(3) (3) (19) 1 (7) (9) (19) (38) (27) (56)
Net Income
0 0 0 1 1 1 1 0 1 1
Depreciation
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Revenue/Sh
(340.00) (205.54) (320.00) 15.56 (60.00) (40.00) (80.00) (42.96) (5.84) (11.28)
Earnings/Sh
(373.99) (237.95) (65.07) (89.17) (52.46) (31.85) (45.91) (15.93) (5.53) (8.69)
Cash Flow/Sh
(1.17) (1.41) (0.07) 0.00 (0.06) (0.45) (0.10) 6.30 (0.05) 0.07
Capex/Sh
(375.16) (239.36) (65.14) (89.17) (52.52) (32.30) (46.01) (9.63) (5.59) (8.61)
Free CF/Sh
(152.73) (57.15) (256.80) 8.11 3.91 28.85 (10.84) (2.43) 14.94 4.04
Book Value/Sh
0 0 0 0 0 0 0 1 5 5
Shares
— — — — — — — — — —
PE Ratio
— — — — — — — — — —
PS Ratio
— — — — — — — — — —
PB Ratio
— — — — — — — — — —
EV/Sales
— — — — — — — — — —
EV/FCF
(4) (3) (4) (6) (6) (6) (13) (14) (25) (43)
Op' Cash Flow
0 0 0 — 0 0 0 6 0 0
Capex
(4) (3) (4) (6) (6) (7) (13) (8) (25) (43)
FCF
0 0 (14) 1 2 6 (3) (2) 66 19
Working Cap'
— 0 1 0 1 2 2 4 — —
Total Debt
0 0 0 (1) (2) (7) 1 (6) (68) (26)
Net Debt
(1) (1) (16) 1 0 6 (3) (2) 68 20
Sh' Equity
(182.72%) (939.88%) (1,526.80%) 53.20% (281.07%) (136.06%) (205.43%) (357.64%) (62.73%) (110.66%)
ROA
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
ROIC
184.06% 127.65% 200.65% (14.01%) (1,313.58%) (269.90%) (1,364.21%) 1,464.81% (80.48%) (126.85%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Oct 2013 · latest quarter Jul 2014

Skye Bioscience, Inc. (SKYE) key facts

  • Skye Bioscience, Inc. (SKYE) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of September 25, 2026, SKYE traded at $1.67, a market capitalization of $7.5 million.
  • Return on equity was −126.9% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Skye Bioscience, Inc. (SKYE) Latest News

News by impact score

Fine-tune

17 Aug

4

Skye Bioscience Inc announces strategic pivot to Fibrex in Q2 2026 earnings call highlights. Strategic pivot to Fibrex represents major move that could significantly alter company's trajectory and investor sentiment.

14 Aug

5

Skye Bioscience enters transaction agreement with Redx Pharma and secures $125 million in financings. Transaction agreement with Redx Pharma plus $125 million financing will fundamentally redefine Skye Bioscience's competitive position and long-term prospects.

20 May

3

Skye Bioscience's Cohort Review Committee approved opening Cohort 2 after favorable safety data from the first four participants treated in Cohort 1. Favorable early safety data enabling next cohort advances clinical development with moderate effect on company trajectory.

12 May

3

Skye Bioscience, Inc. (SKYE) reported first quarter 2026 financial results and provided a business update. Q1 2026 financial results and business update affect financial performance and operational insights but are routine quarterly disclosures.

11 May

3

Skye Bioscience, Inc. (SKYE) reported first quarter 2026 financial results and provided a business update. Quarterly financial results and business updates affect key financial performance metrics and investor sentiment.

2 Apr

4

Skye Bioscience treats first patient in nimacimab higher-dose expansion study evaluating exposure-response to inform Phase 2b dose selection for GLP-1 combination development. Dosing first patient in higher-dose nimacimab study advances Phase 2b planning for GLP-1 combos, marking significant clinical progress in obesity pipeline.

11 Mar

4

Skye Bioscience Inc (SKYE) Q4 2025 earnings call highlights pioneering advances in obesity treatments. Pioneering advances in obesity treatments represent major strategic progress boosting SKYE's pipeline and investor sentiment.

10 Mar

3

Skye Bioscience, Inc. (SKYE) reported fourth quarter and full-year 2025 financial results and provided a business update. Quarterly and annual financial results with business updates moderately influence financial performance and investor sentiment.

2 Feb

4

Skye Bioscience, Inc. reported positive interim results from the CBeyond Phase 2a extension study for Nimacimab in combination with Semaglutide. The study demonstrated promising efficacy and safety profiles, indicating potential benefits for patients. These results may enhance the company's position in the market and support further development of the treatment. Positive interim study results could significantly influence Skye's future performance and market positioning.

29 Jan

4

Skye Bioscience, Inc. highlighted the attributes of its peripherally-restricted CB1 inhibitor antibody at the Keystone Obesity Conference. The company emphasized the potential of this innovative treatment in addressing obesity and related metabolic disorders, showcasing its unique mechanism of action and safety profile. This presentation aims to position Skye as a key player in the obesity treatment landscape, leveraging its proprietary technology to develop effective therapies. The presentation at a significant conference indicates a strategic move that could enhance product positioning and investor sentiment.

21 Jan

3

Skye Bioscience, Inc. (SKYE) will present a poster at the Keystone Obesity Conference, showcasing its research and developments in addressing obesity-related health issues. The conference is a significant event for professionals in the field, providing a platform for sharing innovative findings and advancements. Skye's participation highlights its commitment to tackling obesity through scientific exploration and collaboration with industry experts. Participation in a prominent conference may enhance visibility and networking opportunities, potentially influencing future collaborations and innovations.

12 Jan

4

Skye Bioscience, Inc. (SKYE) has outlined its corporate outlook for 2026, focusing on advancements in its cannabinoid-based therapies. The company aims to enhance its product pipeline and expand its market presence, emphasizing research and development efforts. Key milestones include potential partnerships and regulatory approvals that could drive growth and innovation in the coming years. The outlined strategic initiatives and potential partnerships could significantly alter the company's trajectory and investor sentiment.

3

Skye Bioscience, Inc. (SKYE) faces significant risks as it operates in a volatile market characterized by regulatory uncertainties and competitive pressures. The company's focus on cannabinoid-based therapies may not guarantee success, given the challenges in clinical development and market acceptance. Investors should be cautious, as the potential for substantial returns is accompanied by equally substantial risks. The company's position in a high-risk market with regulatory challenges and competition may moderately influence its financial performance and investor sentiment.

7 Jan

4

Halozyme Therapeutics has entered a partnership with Skye Bioscience to utilize its ENHANZE technology for obesity treatment. This collaboration aims to enhance the delivery of therapeutics, potentially improving patient outcomes in obesity management. The partnership is expected to leverage Skye's expertise in cannabinoid-based therapies alongside Halozyme's innovative delivery system, marking a significant step in addressing obesity-related health issues. The partnership represents a major strategic move that could significantly enhance Skye's product offerings and market position in the obesity treatment sector.

5 Jan

4

Halozyme and Skye Bioscience, Inc. have entered into a global collaboration and license agreement to evaluate Nimacimab co-formulated with ENHANZE® for obesity treatment. This partnership aims to leverage Halozyme's ENHANZE® technology to enhance the delivery of Nimacimab, potentially improving its efficacy in addressing obesity. The collaboration signifies a strategic move for both companies in the growing obesity treatment market. The collaboration with Halozyme could significantly enhance Skye Bioscience's product offerings and market position in the obesity treatment sector.

24 Nov

3

Skye Bioscience, Inc. (SKYE) announced its participation in upcoming investment conferences, which are expected to provide opportunities for engagement with investors and stakeholders. The company aims to showcase its developments and strategic initiatives in the biotechnology sector, potentially enhancing its visibility and market presence. Participation in investment conferences may moderately influence investor sentiment and visibility but is not expected to significantly alter the company's trajectory.

13 Nov

4

Skye Bioscience, Inc. (SKYE) is highlighted for its innovative approaches to obesity treatment showcased at ObesityWeek 2025. The company is leveraging breakthrough research to reshape the obesity market landscape, potentially enhancing its competitive positioning and market presence. These advancements may lead to significant developments in product offerings and strategic initiatives aimed at addressing obesity-related health issues. Breakthrough results presented at a major conference indicate significant potential for strategic advancements and market influence.

11 Nov

4 transcript

Skye Bioscience, Inc. (SKYE) reported promising results from its recent study during the Q3 2025 earnings call, highlighting advancements in its product pipeline and potential market opportunities. The company emphasized its commitment to developing innovative therapies and discussed strategic plans for future growth. Financial performance metrics were also shared, indicating a positive trajectory despite ongoing challenges in the biotech sector. Promising study results and strategic plans indicate significant potential for future growth and market impact.

10 Nov

3

Skye Bioscience, Inc. (SKYE) reported its financial results for the third quarter of 2025, highlighting key metrics and updates on its business operations. The company continues to focus on its development pipeline and strategic initiatives aimed at enhancing its market position. Financial performance indicators showed progress, with specific attention to revenue growth and expense management. Management provided insights into future plans and ongoing projects, emphasizing their commitment to innovation in the biotech sector. The financial results and business updates indicate moderate progress that may influence investor sentiment and operational aspects.

5 Nov

4

Skye Bioscience, Inc. (SKYE) presented a late-breaking oral abstract at ObesityWeek 2025, showcasing significant improvements in rebound weight gain among participants. The findings suggest potential advancements in obesity treatment strategies, highlighting the company's commitment to addressing weight management challenges. The presentation of significant findings at a major conference could enhance investor sentiment and position the company favorably in the obesity treatment market.

3

Skye Bioscience, Inc. (SKYE) will announce its financial results for the third quarter of 2025 and provide a business update on November 10, 2025. This announcement is anticipated by investors and stakeholders as it may offer insights into the company's performance and strategic direction. The upcoming financial results and business update could moderately influence investor sentiment and perceptions of the company's performance.

7 Oct

4

Skye Bioscience, Inc. (SKYE) experienced a 51% decline in stock value following the release of Phase 2a trial results for Nimacimab, which did not meet primary endpoints. The disappointing outcomes have raised concerns about the drug's efficacy and future development. Investors reacted negatively, leading to a significant drop in market confidence. The company is now faced with the challenge of reassessing its strategy and potential next steps for Nimacimab, which could include further trials or exploring alternative treatments. The failure of the Phase 2a trial results is likely to significantly impact Skye Bioscience's future prospects and investor sentiment.

6 Oct

4

Skye Bioscience, Inc. announced topline results from its CBeyond™ Phase 2a clinical trial, evaluating Nimacimab both as a monotherapy and in combination with other treatments. The data demonstrated promising efficacy and safety profiles, suggesting potential for further development in treating specific conditions. The company plans to advance its clinical programs based on these findings. The positive Phase 2a data could significantly influence Skye Bioscience's future product development and market positioning.

4

Skye Bioscience, Inc. (SKYE) experienced a significant drop in share prices after its obesity drug failed to meet expectations in a crucial clinical study. The results raised concerns about the drug's efficacy and the company's future prospects in the competitive obesity treatment market. Investors reacted negatively, leading to a sharp decline in stock value as analysts reassessed the company's potential for success in this therapeutic area. The failure of the obesity drug in a key study is likely to significantly impact Skye's future performance and investor sentiment.

3

Skye Bioscience, Inc. (SKYE) has been identified as one of the most active stocks in the market, reflecting heightened trading activity and investor interest. The company's recent developments and market performance have contributed to its visibility among investors, indicating potential shifts in market sentiment and engagement with its stock. Increased trading activity suggests a moderately noticeable influence on investor sentiment and market performance.

19 Sep

4

Skye Bioscience, Inc. is developing a new drug aimed at combating obesity, which may offer a safer alternative to existing treatments. The drug leverages cannabinoid technology to potentially reduce appetite and promote weight loss without the adverse effects commonly associated with current obesity medications. Early studies show promise, and the company is optimistic about the drug's efficacy and safety profile. If successful, this could position Skye as a key player in the obesity treatment market, addressing a significant health issue affecting millions. The development of a new obesity drug could significantly alter Skye's market position and investor sentiment.

4

Skye Bioscience, Inc. presented Phase 1b data for its peripheral CB1-inhibiting antibody, Nimacimab, at the EASD Annual Meeting. The data demonstrated promising results in reducing body weight and improving metabolic parameters in patients with obesity and type 2 diabetes. This research highlights the potential of Nimacimab as a therapeutic option for these conditions, indicating a positive step forward in Skye's development pipeline. Promising Phase 1b data for Nimacimab could significantly influence Skye's future product offerings and market position in diabetes treatment.

4 Sep

4

Skye Bioscience, Inc. announced that its CB1 inhibitor, Nimacimab, has shown superior weight loss results compared to Monlunabant and demonstrates unique mechanisms of action. Additionally, Nimacimab continues to exhibit enhanced effectiveness when combined with Tirzepatide, leading to sustained weight maintenance after treatment in a diet-induced obesity model. The advancements in Nimacimab's efficacy and its combination with Tirzepatide could significantly influence Skye's market position and investor sentiment.

2 Sep

4

Skye Bioscience, Inc. has completed the 26-week treatment phase of its Phase 2a CBeyond™ study, which evaluates the efficacy and safety of its proprietary cannabinoid-based therapy for treating glaucoma. The study aims to assess the therapy's impact on intraocular pressure and overall ocular health. Results from this phase are expected to provide critical insights for further development and potential commercialization of the treatment. Completion of the treatment phase in a pivotal study could significantly influence future product development and investor sentiment.

27 Aug

4

Skye Bioscience, Inc. will host a virtual Key Opinion Leader (KOL) event to discuss the upcoming topline clinical data readout for its CBeyond™ Phase 2a trial. The event aims to provide insights and perspectives on the trial's results, which are anticipated to be significant for the company's future developments. The upcoming clinical data readout is likely to have a significant impact on Skye Bioscience's strategic direction and investor sentiment.

stockrow.com/SKYE · Data as of Jul 31, 2014 · For information only; not investment advice. · © 2026 stockrow.com