Septerna, Inc.

SEPN Healthcare Biotechnology

Septerna, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $46.0 million, up 4,174.5% from fiscal 2024.

Revenue
+22,375.6%
EPS
+48.2%
Free cash flow
−9.01%

Quarter to June 2026, against a year earlier

48.95 1.60 +3.38%
Market cap
$2.2B
P/E
0.0×
Fwd P/E
−32.6×
Dividend yield
—
F-score
5/9
Altman Z
3.41
Beneish M
32.85
Dividend safety
n/a
Older periods Sep '25 Dec '25 Mar '26 Jun '26
P/E ratio

+8 more quarters

0.00 0.00 0.00 0.00
P/S ratio
37.84 26.85 14.89 15.25
P/FCF ratio
7.21 10.10 9.01 12.83
P/Operating CF
4.94 (82.33) (41.96) (68.01)
P/B ratio
2.15 3.23 2.84 3.90
EV/Sales
16.32 18.34 10.08 11.49
EV/EBITDA
0.00 0.00 0.00 0.00
EV/FCF
3.11 6.90 6.10 9.66
Current Ratio
6.53 4.73 4.71 4.99
Net Debt/EBITDA
(157.33) 25.03 26.97 22.69
Debt/Equity
0.00 0.00 0.00 0.00
Earnings Yield
(8.03%) (3.98%) (3.37%) (1.61%)
Free Cash Flow Yield
13.87% 9.90% 11.10% 7.80%
Free Cash Flow per Share
4.09 (0.34) (0.59) (0.49)
Book value per Share
8.77 8.63 8.46 8.59
Free Cash Flow
181.29 (15.05) (26.46) (22.18)
EV/EBIT
0.00 0.00 0.00 0.00
Other line items

Show all line items

Columns are period end dates · fundamentals updated 25 Oct 2026