Revolution Medicines, Inc.

RVMD Healthcare Biotechnology

Revolution Medicines, Inc.’s revenue for fiscal 2023 (year ended December 2023) was $11.6 million, down 67.3% from fiscal 2022.

Revenue
+1,188.7%
EPS
−18.0%
Free cash flow
−99.1%
Total debt
+322.7%

Quarter to September 2026, against a year earlier

192.56 14.91 +8.39%
Market cap
$38.1B
P/E
0.0×
Fwd P/E
−11.9×
Dividend yield
—
F-score
4/9
Altman Z
7.73
Beneish M
−4.29
Dividend safety
n/a

Insider Decisions last twelve months

Sold, $m 143.32
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — — — —
Sell 5 3 — 9 2 1 9 — 3 15 1 —
Insider Ownership 10.19%

Capital & Financial Ratios $m

Size
Market Cap 38,080.00
Revenue ttm 209.14
Net income ttm (1,870.54)
Free cash flow ttm (1,440.82)
Net debt Q (3,651.38)
Valuation
P/E 0.00
Forward P/E (11.90) (negative: loss-making)
Price / sales 184.79 (above 10: high)
Forward P/S Powerpack
Price / FCF 0.00
Price / book 16.09 (above 6: high)
Financial health
Current ratio Q 8.36 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q (11.04)
Growth
Revenue growth Q +1,188.71% (above 0%: growing)
Operating income growth Q −18.36% (below 0%: shrinking)
EPS, this year −45.56% (below 0%: weak)
EPS, next year A +56.68% (at or above 15%: strong)
Revenue, next year A −97.01% (below 0%: weak)
EPS, past 5 yrs —
EPS, next 5 yrs A +63.75% (at or above 15%: strong)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/S against its own 10 years 61.52%
10-year low 10-year high
P/B against its own 10 years 93.37%
10-year low 10-year high
EV/Sales against its own 10 years 65.30%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 1,853 2,289 2,026 3,651
Receivables 1 — — —
Inventory — — — —
Other — — — —
1,879 2,328 2,075 3,977
2023 2024 2025 Q'26
Payables 62 54 65 101
ST’ Debt — — — —
Other — — — —
144 164 290 476

Compound Annual Growth %

10y 5y 3y
Sales — (10.50%) (35.41%)
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 28.01% 33.53%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (2.29) (3.06) (1.90) — —
’25 (1.13) (1.31) (1.61) (1.86) (5.95)
’24 (0.70) (0.81) (0.94) (1.12) (3.58)
’23 (0.72) (0.92) (0.99) (1.14) (3.86)
’22 (0.78) (0.82) (0.87) (0.63) (3.08)
’21 (0.53) (0.60) (0.72) (0.71) (2.57)
’20 (0.74) (0.46) (0.42) (0.52) (2.01)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 — — 198 — —
’23 7 4 — 1 12
’22 8 9 3 15 35
’21 10 9 1 9 29
’20 12 10 13 9 43
’19 13 12 13 12 50
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (354) (387) (416) — —
’25 (194) (222) (207) (274) (898)
’24 (161) (128) (130) (138) (557)
’23 (62) (67) (100) (121) (351)
’22 (55) (56) (52) (62) (224)
’21 (37) (34) (37) (39) (147)
’20 (28) (20) (27) (25) (100)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (356) (390) (419) — —
’25 (198) (229) (211) (276) (914)
’24 (164) (131) (134) (140) (568)
’23 (64) (68) (103) (123) (358)
’22 (57) (58) (55) (65) (235)
’21 (41) (35) (37) (40) (154)
’20 (29) (20) (28) (26) (103)
Fiscal quarters ending in the months shown.

Valuation

The price implies free cash flow after share-based pay growing 94.4% a year for ten years.

Implied
94.4%
Open the model

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue — — 20 50 43 29 35 12 — — 209 (10.5%) 201 1,258 2,613 +260.7%
Gross margin, % — 0.00 100.00 100.00 100.00 100.00 100.00 100.00 — — 95.62 +100.0 pt
EBT — (31) (42) (52) (109) (187) (249) (440) (601) (1,131) (1,873) +56.7%
EBT margin, % — 0.00 (207.24) (103.99) (252.50) (636.58) (704.14) (3,798.71) 0.00 0.00 (895.52) 0.0 pt
Net income — (31) (42) (48) (108) (187) (249) (436) (600) (1,131) (1,871) +56.7%
Per share, $
Per share, $ Revenue — 0.00 8.77 18.05 0.78 0.40 0.44 0.10 0.00 0.00 0.97 n/m
Earnings — — (21.24) (22.33) (2.01) (2.57) (3.08) (3.86) (3.58) (5.95) (9.11) (16.6%)
Cash flow — (14.60) 0.53 (17.89) (1.82) (2.02) (2.78) (3.10) (3.32) (4.72) (6.66) (13.2%)
Capex — (0.91) (0.65) 1.30 (0.05) (0.09) (0.13) (0.07) (0.06) (0.08) (0.04) (25.8%)
Free cash flow — (15.51) (0.12) (16.59) (1.88) (2.11) (2.92) (3.17) (3.38) (4.81) (6.70) (13.6%)
Book value — 0.00 42.04 55.01 8.65 8.28 8.50 16.14 13.50 8.58 11.17 n/m
Shares, m — 2 2 3 55 73 81 113 168 190 204 +80.0%
Valuation, ×
Valuation, × P/E — — 0.00 0.00 0.00 0.00 0.00 0.00 — — 0.00 0.0
P/S — — 1.60 1.60 50.54 62.35 52.30 148.60 — — 184.79 52.8
P/B — — 0.00 0.00 4.58 3.04 2.70 2.19 — — 16.09 2.1
EV/Sales — — (0.85) (0.85) 40.96 44.77 35.68 81.86 — — 172.29 33.6
EV/FCF — — 0.93 0.93 (17.09) (8.56) (5.37) (6.15) — — (25.01) (5.9)
Cash, $m
Cash, $m Operating cash flow — (25) 1 (50) (100) (147) (224) (351) (557) (898) (1,431) +56.3%
Capex — (2) (1) 4 (3) (7) (11) (8) (10) (16) (9) +33.6%
Free cash flow — (27) 0 (46) (103) (154) (235) (358) (568) (914) (1,441) +55.5%
Balance, $m
Balance, $m Working capital — 2 55 91 407 529 598 1,735 2,164 1,785 3,501 +136.2%
Net debt — (9) (70) (123) (412) (517) (588) (1,853) (2,289) (1,757) (3,651) +93.1%
Shareholders’ equity — — 97 153 475 603 685 1,826 2,265 1,631 2,402 +49.7%
Returns, %
Returns, % ROA — (37.00) (57.24) (31.65) (28.02) (28.66) (32.09) (30.37) (25.98) (46.06) (57.07) (9.1) pt
ROIC — 0.00 (93.10) (113.59) (109.95) (136.74) (165.26) 0.00 0.00 0.00 0.00 0.0 pt
ROE — 39.62 55.43 47.44 (68.54) (34.74) (38.63) (34.75) (29.33) (58.07) (93.56) (97.7) pt
People
People Employees — — 90 95 125 188 246 378 534 883 — +38.6%
Revenue/emp, $m — — 0.22 0.53 0.34 0.16 0.14 0.03 0.00 0.00 — n/m
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2023 · latest quarter Sep 2026 · fundamentals updated 4 Nov 2026

Business profile

Updated

Revolution Medicines develops targeted medicines for cancers driven by abnormal RAS proteins, which help cancer cells grow and survive. Founded in 2014 and headquartered in Redwood City, it sells RASONQUE, also known as daraxonrasib, in the United States for eligible patients with metastatic pancreatic cancer. The FDA approved the medicine.

RASONQUE is an oral medicine designed to inhibit several active forms of RAS. The company’s approach uses a proprietary platform to create small molecules that bind to active RAS proteins. Its medicines are designed for use alone, with another RAS inhibitor or alongside other treatments such as chemotherapy or immunotherapy.

Revolution Medicines, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
ARGX argenex SE $56.3B 29.8× 30.1× +52.13% (above 0%: growing) +43.85% (above 0%: growing) +537.51% (above 0%: growing) 90.58% 27.70% Compare
ONC BeOne Medicines Ltd. - Sponsored ADR $40.4B 65.9× 48.8× +33.81% (above 0%: growing) +143.68% (above 0%: growing) +33.59% (above 0%: growing) 88.52% 22.15% Compare
RPRX Royalty Pharma PLC $39.0B 44.8× 27.3× +13.26% (above 0%: growing) −51.52% (below 0%: shrinking) +364.63% (above 0%: growing) 100.00% 59.53% Compare
RVMD Revolution Medicines, Inc. $38.1B — (loss-making) — (loss-making) +1,188.71% (above 0%: growing) n/m −99.06% (below 0%: shrinking) 100.00% (188.88%)
GMAB Genmab A/S Sponsored ADR $31.5B 41.7× 47.3× +24.86% (above 0%: growing) −9.26% (below 0%: shrinking) −7.69% (below 0%: shrinking) 92.73% 32.47% Compare
ROIV Roivant Sciences Ltd. $26.5B — (loss-making) — (loss-making) −33.55% (below 0%: shrinking) n/m −29.99% (below 0%: shrinking) 80.31% (25,380.93%) Compare
INCY Incyte Corporation $24.1B 56.3× 55.6× +14.00% (above 0%: growing) n/m −232.97% (below 0%: shrinking) 93.02% (45.49%) Compare
INSM Insmed, Inc. $23.9B — (loss-making) — (loss-making) +268.43% (above 0%: growing) n/m +81.06% (above 0%: growing) 85.09% (17.04%) Compare
BNTX BioNTech SE Sponsored ADR $21.6B — (loss-making) — (loss-making) −16.42% (below 0%: shrinking) n/m −123.82% (below 0%: shrinking) 91.99% 9.70% Compare
Median of peers $29.0B 44.8× 47.3× +19.43% +17.30% +12.95% 91.29% 15.93%

All 621 Biotechnology stocks →

Analyst rating changes each firm’s latest, last six months

Firm Date Action Rating Target
RBC Oct 20, 2026 Reiterated Outperform 260.00
Truist Oct 20, 2026 Target raised Buy 240.00 → 241.00

Largest institutional holders 13F, quarter to 30 June 2026

Held by institutions 99.84%
Held by the ten largest 52.04%
Holder Shares Stake Change
Vanguard 18.94m 8.84% +1.70m
BlackRock 13.70m 6.39% +2.48m
FARALLON CAPITAL MANAGEMENT, L.L.C. 13.55m 6.32% −54.00k
Fidelity (FMR) 12.20m 5.69% +3.74m
BAKER BROS. ADVISORS LP 11.44m 5.34% +1.89m
Jupiter Topco 10.71m 5.00% +10.71m
Darwin Global Management, Ltd. 10.63m 4.96% +8.42m
Nextech Invest Ltd. 7.60m 3.55% 0.00
Paradigm Biocapital Advisors LP 6.36m 2.97% −294.38k
UBS 6.36m 2.97% +1.47m
13F filings for the quarter to 30 June 2026: long positions in US-listed shares reported by managers with $100m or more, ~45 days after the quarter.

Pay and ownership Proxy statement filed 27 April 2026

Chief executive’s pay

Year Total pay Actually paid $100 invested
2025 14.67m 37.06m 201.19
2024 10.08m 20.33m 110.48
2023 10.41m 14.00m 72.44
2022 7.22m 8.64m 60.17
2021 7.83m (3.47m) 63.58

Ownership

Directors and executive officers, together 7.60%
Entities affiliated with Farallon Capital Partners, L.P. 7.30%
Entities affiliated with Janus Henderson Group PLC 5.70%
Total pay is as the Summary Compensation Table states it; actually paid revalues the year’s share awards at its end, as the SEC’s pay-versus-performance rule asks. $100 invested is what $100 in the company’s shares at the start of the earliest year shown was worth at each year’s end. Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Revolution Medicines, Inc. (RVMD) Latest News

17 Oct

Impact 4 · · Simply Wall St.

RVMD metrics, ten years each

stockrow.com/RVMD · Data as of Nov 4, 2026 · For information only; not investment advice. · © 2026 stockrow.com