Oruka Therapeutics, Inc.

ORKA Healthcare Biotechnology

In the quarter to June 2026, EPS fell 19.6% and free cash flow fell 43.0%, each against the same quarter a year earlier.

71.93 1.94 −2.63%
Market cap
$4.9B
P/E
0.0×
Fwd P/E
—
Dividend yield
0.00%
F-score
n/a
Altman Z
n/a
Beneish M
n/a
Dividend safety
n/a

Insider Decisions trades per month

Total sells 336.97
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — 1 2 1 6 1 4 7 4 3 9 3
Insider Ownership 6.49%

Capital & Financial Ratios $m

Market Cap 4,890.00
Revenue —
Net Income (132.89)
Free Cash Flow (101.15)
Net Debt (873.56)
Current Ratio 38.51 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E —
P/S ratio 0.00
P/B ratio 4.07
Past 5Y EPS Growth —
This Y EPS Growth (29.94%) (below 0%: weak)
Next Y EPS Growth (17.62%) (below 0%: weak)
Next Y revenue growth —
Next 5Y EPS Growth (25.11%) (below 0%: weak)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/B against its own 10 years 94.14%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate 0.00
Annual Dividend Yield 0.00%
total individual payouts
2024 1.59
1.59
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 37 376 337 874
Receivables — — — —
Inventory — — — —
Other 0 — — —
38 377 344 885
2023 2024 2025 Q'26
Payables 0 9 4 8
ST’ Debt — — — —
Other — — — —
1 13 15 23

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value 28.63% 58.94% 124.56%

Revenue $m

Year
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (24) (33) — — —
’25 (21) (23) (22) (23) (88)
’24 (2) (3) (35) (19) (58)
’23 (2) (1) (2) (1) (5)
’22 (4) (3) (2) (1) (11)
’21 (5) (4) (5) (5) (19)
’20 (2) (1) (2) (3) (8)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (24) (33) — — —
’25 (21) (23) (22) (23) (88)
’24 (2) (3) (35) (19) (58)
’23 (2) (1) (2) (1) (5)
’22 (4) (3) (2) (1) (11)
’21 (5) (4) (5) (5) (19)
’20 (2) (1) (2) (3) (8)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.48) (0.55) — — —
’25 (0.40) (0.46) (0.55) (0.54) (1.85)
’24 (1.68) (6.96) (1.46) (0.49) (5.79)
’23 (1.08) (1.20) (1.20) (0.96) (4.44)
’22 (2.76) (2.64) (1.92) (0.96) (8.28)
’21 (3.96) (4.08) (3.96) (4.80) (16.69)
’20 (9.96) (8.76) (3.96) (7.32) (24.85)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1.1
1Buy 2 3Hold 4 5Sell

Ten years at a glance

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 464.40 226.80 56.16 58.68 26.52 25.68 20.52 19.32 17.64 5.49

Analyst estimates 2026–2028

Powerpack
High 1,062.72 626.40 421.20 245.40 264.00 66.00 31.08 32.40 53.88 32.64
People
People Employees 20 20 15 13 14 19 12 5 36 68
Revenue/emp, $m 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Income, $m
Income, $m Revenue — — — — — — — — — —
Gross margin, % 0.00 0.00 0.00 0.00 0.00 0.00 0.00 — — —
EBT (16) (19) (8) (6) (10) (19) (10) (5) (84) (105)
EBT margin, % 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Net income (16) (18) (8) (5) (10) (19) (10) (5) (84) (105)
Depreciation 0 0 0 0 0 0 0 0 (2) (5)
Per share, $
Per share, $ Revenue 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Earnings (390.80) (382.17) (123.07) (49.82) (24.85) (16.69) (8.28) (4.44) (5.79) (1.85)
Cash flow (356.83) (361.74) (128.61) (43.65) (19.69) (16.20) (9.09) (4.18) (3.44) (1.93)
Capex (0.29) (0.06) (0.06) (0.04) (0.05) (0.04) 0.00 0.00 (0.01) 0.00
Free cash flow (357.12) (361.80) (128.67) (43.68) (19.74) (16.24) (9.09) (4.18) (3.46) (1.94)
Book value 528.43 212.73 94.10 69.18 118.59 44.07 34.72 30.83 22.77 10.35
Shares, m 0 0 0 0 0 1 1 1 17 46
Valuation, ×
Valuation, × P/E — — — — — — — — — —
P/S — — — — — — — — — —
P/B — — — — — — — — — —
EV/Sales — — — — — — — — — —
EV/FCF — — — — — — — — — —
Cash, $m
Cash, $m Operating cash flow (15) (17) (8) (5) (8) (19) (11) (5) (58) (88)
Capex 0 0 0 0 0 0 0 — 0 0
Free cash flow (15) (17) (8) (5) (8) (19) (11) (5) (58) (88)
Balance, $m
Balance, $m Working capital 19 10 6 8 46 51 42 37 364 328
Total debt — — — 0 0 0 0 — — —
Net debt (21) (12) (7) (8) (49) (53) (42) (37) (376) (337)
Shareholders’ equity 22 10 6 8 47 51 42 37 382 472
Returns, %
Returns, % ROA (51.23) (99.96) (82.68) (71.38) (33.03) (36.68) (20.26) (13.19) (38.59) (23.84)
ROIC (1,007.09) 0.00 0.00 0.00 0.00 0.00 0.00 0.00 (837.93) (56.55)
ROE (54.57) (113.89) (97.30) (80.37) (35.98) (39.61) (21.41) (13.57) (40.22) (24.86)
Negative figures in brackets.

All 10 years →

Charts ten years each

Oruka Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
MIRM Mirum Pharmaceuticals, Inc. $5.4B — (loss-making) — (loss-making) +37.92% (above 0%: growing) n/m −681.46% (below 0%: shrinking) 82.78% (24.14%) Compare
ERAS Erasca, Inc. $5.2B — (loss-making) — — n/m −4.67% (below 0%: shrinking) 0.00% 0.00% Compare
COGT Cogent Biosciences, Inc. $5.1B — (loss-making) — (loss-making) −69.41% (below 0%: shrinking) n/m −42.01% (below 0%: shrinking) 0.00% 0.00% Compare
PTCT PTC Therapeutics, Inc. $5.1B — (loss-making) 110× +101.55% (above 0%: growing) n/m +295.69% (above 0%: growing) 94.47% 41.32% Compare
CRSP CRISPR Therapeutics AG $5.0B — (loss-making) — (loss-making) +1,041.37% (above 0%: growing) n/m +26.19% (above 0%: growing) 100.00% (1,151.84%) Compare
TVTX Travere Therapeutics, Inc. $5.0B — (loss-making) 196× +48.17% (above 0%: growing) n/m +604.22% (above 0%: growing) 98.72% 2.33% Compare
SRRK Scholar Rock Holding Corporation $5.0B — (loss-making) — (loss-making) +605.03% (above 0%: growing) n/m +8.88% (above 0%: growing) 0.00% 0.00% Compare
ORKA Oruka Therapeutics, Inc. $4.9B — (loss-making) — — n/m −43.00% (below 0%: shrinking) 0.00% 0.00%
DFTX Definium Therapeutics, Inc. $4.6B — (loss-making) — — n/m −78.31% (below 0%: shrinking) 0.00% 0.00% Compare
Median of peers $5.0B — — +74.86% — +2.11% 41.39% 0.00%

All 614 Biotechnology stocks →

Oruka Therapeutics, Inc. (ORKA) key facts

  • Oruka Therapeutics, Inc. (ORKA) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, ORKA traded at $71.93, a market capitalization of $4.9 billion.
  • Oruka Therapeutics, Inc. does not currently pay a dividend.
  • Return on equity was −24.9% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Oruka Therapeutics, Inc. (ORKA) Latest News

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