Lexicon Pharmaceuticals, Inc.

LXRX Healthcare Biotechnology

Lexicon Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $49.8 million, up 60.2% from fiscal 2024.

Revenue
−20.7%
EPS
+21.3%
Free cash flow
+66.1%
Total debt
−8.17%

Quarter to September 2026, against a year earlier

1.79 0.18 +11.18%
Market cap
$716.4M
P/E
0.0×
Fwd P/E
−8.4×
Dividend yield
—
F-score
4/9
Altman Z
−12.11
Beneish M
−1.17
Dividend safety
n/a

Lexicon Pharmaceuticals, Inc. (LXRX) P/E ratio

Alert me on P/E ratio

Lexicon Pharmaceuticals, Inc. has no meaningful P/E ratio: its trailing twelve-month earnings is negative. Over the past ten years it has ranged from 0.0× (November 2026) to 11.9× (September 2021) — the current reading is the lowest in ten years.

P/E ratio, daily

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Annual newest first

Period P/E ratio Change
FY2025 0.0× —
FY2024 0.0× —
FY2023 0.0× —
FY2022 0.0× —
FY2021 0.0× —
FY2020 0.0× —
FY2019 3.4× —
FY2018 0.0× —
FY2017 0.0× —
FY2016 0.0× —

Quarterly newest first

Period P/E ratio Change
Sep 2026 0.0× —
Jun 2026 0.0× —
Mar 2026 0.0× —
Dec 2025 0.0× —
43 more quarters

Against its own ten years

Low 0.0× High 11.9×
Ten-year median 0.0×
Current reading's percentile 89

P/E ratio against peers

What P/E ratio is

Price to Earnings Ratio shows how much investors pay for each dollar of a company’s annual profit per share.

Stock Price ÷ EPS (Basic) (TTM)

The full definition of P/E ratio →

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