Lexicon Pharmaceuticals, Inc.

LXRX Healthcare Biotechnology

Lexicon Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $49.8 million, up 60.2% from fiscal 2024. In the quarter to June 2026, revenue fell 97.6%, EPS fell 800.0%, free cash flow fell 154.1% and total debt fell 8.32%, each against the same quarter a year earlier. Revenue growth for three consecutive years; insiders bought in the last twelve months.

1.52 0.13 −7.88%
Market cap
$734.2M
P/E
0.0×
Fwd P/E
−12.1×
Dividend yield
—
F-score
4/9
Altman Z
−12.11
Beneish M
−1.17
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
P/E ratio
0.00 0.00 0.00 3.40 0.00 0.00 0.00 0.00 0.00 0.00
Piotroski F-Score
1 2 1 7 1 3 2 2 5 4
Altman Z-Score
(1.20) (2.87) (6.29) (0.95) (4.82) (1.96) (9.98) (11.00) (9.56) (12.11)
P/S ratio
18.61 11.62 11.12 1.37 15.80 1,925.73 2,372.72 292.02 7.62 8.38
P/FCF ratio
0.00 0.00 0.00 3.88 0.00 0.00 0.00 0.00 0.00 0.00
Altman Z″-Score (non-manufacturers)
(7.18) (8.76) (16.26) (3.51) (16.94) (31.38) (24.59) (25.27) (20.51) (33.00)
P/Operating CF
(30.23) (31.59) (25.90) (18.09) (11.07) (25.14) (15.29) (6.96) (11.02) (24.23)
Beneish M-Score
8.68 (2.29) (1.55) 2.15 (3.60) (10.38) (1.14) 6.84 18.61 (1.17)
P/B ratio
9.37 15.60 0.00 3.76 2.42 5.05 2.82 3.78 1.62 3.88
EV/Sales
15.52 10.91 12.46 1.29 9.96 1,642.30 1,736.13 234.53 3.23 7.54
EV/EBITDA
0.00 0.00 0.00 2.83 0.00 0.00 0.00 0.00 0.00 0.00
EV/FCF
(6.99) (5.39) (5.30) 3.64 (1.81) (5.55) (2.68) (1.74) (0.56) (5.45)
Current Ratio
2.17 3.05 4.72 5.17 3.37 4.02 6.08 5.60 5.44 4.88
Net Debt/EBITDA
1.97 0.51 (0.86) (0.18) 3.19 0.97 0.89 0.42 0.71 0.91
Debt/Equity
0.64 3.60 (9.28) 2.09 0.08 0.02 0.43 1.07 0.69 0.50
ROE
(59.31%) (109.00%) (575.96%) 286.97% (42.84%) (65.01%) (88.37%) (168.50%) (167.66%) (39.72%)
ROA
(23.31%) (26.97%) (33.45%) 37.08% (18.85%) (51.52%) (61.56%) (83.60%) (75.93%) (20.83%)
ROIC
0.00% (2,594.22%) (110.26%) 97.55% (182.69%) (186.85%) (219.91%) (475.14%) (1,485.93%) (46.81%)
Return on Tangible Assets
(61.82%) (52.52%) (79.08%) 45.43% (52.67%) (129.11%) (85.12%) (120.50%) (98.51%) (60.73%)
Average Days of Receivables
34.50 19.21 34.21 64.07 6.01 17.15 73.53 306.19 40.79 17.47
Earnings Yield
(8.98%) (11.47%) (17.32%) 29.40% (16.08%) (15.48%) (30.65%) (50.31%) (86.49%) (12.17%)
Free Cash Flow Yield
(11.92%) (17.43%) (21.16%) 25.80% (34.83%) (15.38%) (27.34%) (46.18%) (75.93%) (16.50%)
Free Cash Flow per Share
(1.69) (1.76) (1.41) 1.07 (1.19) (0.61) (0.54) (0.73) (0.56) (0.19)
Book value per Share
1.52 0.65 (0.25) 1.10 1.41 0.78 0.71 0.42 0.46 0.30
Free Cash Flow
(175.86) (185.62) (148.70) 113.74 (132.04) (88.24) (90.18) (162.37) (179.81) (67.85)
EV/EBIT
0.00 0.00 0.00 2.93 0.00 0.00 0.00 0.00 0.00 0.00
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