Saturday 17 October 2026 Export IONS’s income statement to Excel — free account

Ionis Pharmaceuticals, Inc.

Ionis Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $943.7 million, up 33.8% from fiscal 2024. In the quarter to June 2026, revenue fell 40.7%, EPS fell 188.5%, free cash flow grew 299.3% and total debt rose 116.0%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

42.94 1.18 −2.67%

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Market cap: $7.3B
P/E: 0.0×
Fwd P/E: −20.8×
Dividend yield: —
F-score: 4/9
Altman Z: 2.12
Beneish M: −3.13
Dividend safety: n/a

Overview Business Profile Financial Analysis Income Statement Balance Sheet Cash Flow Metrics & Ratios 10-Q 10-K

	Jun '26	Mar '26	Dec '25	Sep '25	Older periods
ROE Full definition →	(105.50%)	(67.62%)	(70.80%)	(40.04%)	+8 more TTM periods Free account
Piotroski F-Score Full definition →	2	3	4	5
ROA Full definition →	(18.90%)	(10.44%)	(11.69%)	(8.39%)
ROIC Full definition →	0.00%	0.00%	0.00%	0.00%
Return on Tangible Assets Full definition →	(24.25%)	(13.84%)	(16.35%)	(14.89%)
Average Days of Receivables Full definition →	24.57	25.42	25.55	9.29
Free Cash Flow per Share Full definition →	(3.43)	(5.93)	(2.04)	(1.94)
Free Cash Flow Full definition →	(567.50)	(977.73)	(325.67)	(309.48)
Capital Expenditures Full definition →	(71.07)	(67.10)	(57.08)	(62.47)
Other line items
Cash ROIC Full definition →	(14.76%)	(26.01%)	(6.58%)	(8.96%)
Accounts Receivable Turnover Full definition →	15.69	18.66	11.93	45.47
Accounts Payable Turnover Full definition →	0.45	0.80	0.45	1.01
Inventory Turnover Full definition →	0.54	2.04	1.41	0.61
Average Days of Payables Full definition →	1,087.09	545.12	644.29	443.85
Days of Inventory on Hand Full definition →	1,158.40	116.38	230.53	324.38
Tax Rate Full definition →	0.01	0.01	0.00	(0.01)
Research and Development Expense of Revenue Full definition →	105.79%	87.42%	97.02%	91.16%
Selling, General and Administrative Expense of Revenue Full definition →	60.38%	44.22%	41.74%	36.38%
Share Based Compensation of Revenue Full definition →	18.69%	13.93%	14.19%	13.10%
Interest Coverage Full definition →	(6.64)	(3.91)	(4.22)	(3.06)
Operating CF/Net income Full definition →	0.88	2.79	0.70	0.96
Depreciation/Fixed assets Full definition →	0.09	0.07	0.05	0.00
Capex/Depreciation Full definition →	(4.93)	(7.03)	(9.73)	223.91
Revenue per Share Full definition →	5.28	6.42	5.90	6.05
Operating CF per Share Full definition →	(3.00)	(5.52)	(1.68)	(1.55)
Capex per Share Full definition →	(0.43)	(0.41)	(0.36)	(0.39)
Capex to Sales Full definition →	0.08	0.06	0.06	0.06

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Columns are period end dates

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