IO Biotech, Inc. IOBTQ

0.00 0.00 NaN as of 25 Sep
Market cap
$3.5M
P/E
0.0×

Insider Decisions

in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 9.85%

Capital & Financial Ratios

Market Cap 3.45
Revenue —
Net Income (88.35)
Free Cash Flow (81.06)
Net Debt (14.00)
Current Ratio 2.01
Debt/Equity 18.29
P/E ratio 0.00
P/S ratio 0.00
P/B ratio 0.00
Past 5Y EPS Growth (27.25%)
This Y EPS Growth 59.09%
Next Y EPS Growth 66.67%
Next 5Y EPS Growth 41.92%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2022 2023 2024 Q'25
Cash 143 143 60 31
Receivables — — — —
Inventory — — — —
Other — — — —
148 147 65 37
2022 2023 2024 Q'25
Payables 4 4 5 6
ST’ Debt — — — —
Other — — — —
11 16 19 18
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% (39.46%)

Revenue

Year
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (23) (20) (18) — —
’24 (25) (17) (21) (20) (82)
’23 (15) (18) (16) (23) (72)
’22 (21) (13) (13) (13) (60)
’21 (4) (9) (8) (19) (41)
’20 — — (7) (3) (10)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (23) (20) (18) — —
’24 (25) (17) (21) (20) (82)
’23 (15) (18) (16) (23) (72)
’22 (21) (13) (13) (13) (60)
’21 (4) (9) (8) (19) (41)
’20 — — (7) (3) (10)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (0.34) (0.40) (0.13) — —
’24 (0.30) (0.31) (0.36) (0.48) (1.45)
’23 (0.59) (0.74) (0.43) (0.40) (1.98)
’22 (0.60) (0.64) (0.56) (0.69) (2.48)
’21 (21.15) (216.47) (36.88) 247.15 (17.30)
’20 — — (19.68) — (67.96)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

5
1Buy 2 3Hold 4 5Sell
2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027
— — — — — — 6.02 2.15 0.82 0.66

Analyst estimates 2025–2027

Powerpack
Low Price
— — — — — — 17.88 9.77 3.30 2.10
High Price
— — — — — 19 32 57 68 80
Employees
— — — — — 0 0 0 0 0
Revenue/Emp
— — — — — — — — — —
Revenue
— — — — — — — 0.00% — —
Gross Margin
— — — — (11) (12) (68) (70) (85) (94)
EBT
— — — — 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
EBT Margin
— — 0 — (11) (12) (68) (71) (86) (95)
Net Income
— — — — — — 0 0 0 0
Depreciation
— — — — 0.00 0.00 0.00 0.00 0.00 0.00
Revenue/Sh
— — — — (0.43) (67.96) (17.30) (2.48) (1.98) (1.45)
Earnings/Sh
— — — — (0.31) (56.19) (9.37) (2.07) (1.65) (1.25)
Cash Flow/Sh
— — — — 0.00 0.00 (0.04) (0.02) (0.01) 0.00
Capex/Sh
— — — — (0.31) (56.19) (9.41) (2.10) (1.65) (1.25)
Free CF/Sh
— — — — (0.05) (199.23) 48.88 4.82 3.06 0.71
Book Value/Sh
— — — — 29 0 4 29 44 66
Shares
— — — — — — — — — —
PE Ratio
— — — — — — — — — —
PS Ratio
— — — — — — — — — —
PB Ratio
— — — — — — — — — —
EV/Sales
— — — — — — — — — —
EV/FCF
— — — — (9) (10) (41) (60) (72) (82)
Op' Cash Flow
— — — — — — 0 (1) 0 0
Capex
— — — — (9) (10) (41) (60) (72) (82)
FCF
— — — — (1) 3 211 138 132 45
Working Cap'
— — — — 9 — — 3 — —
Total Debt
— — — — 1 (3) (212) (143) (143) (60)
Net Debt
— — — — (1) (35) 212 139 133 47
Sh' Equity
— — — — (265.67%) (193.61%) (65.80%) (38.20%) (56.91%) (87.44%)
ROA
— — — — 0.00% 0.00% (6,557.57%) 0.00% 0.00% 0.00%
ROIC
— — — — 42.55% 49.61% (84.91%) (40.74%) (63.29%) (106.00%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

IO Biotech, Inc. (IOBTQ) Latest News

News by impact score

Fine-tune

13 Feb

4

IO Biotech, Inc. (IOBT) is being highlighted as a potential investment opportunity due to its recent stock price decline and promising pipeline of immunotherapy treatments. Analysts suggest that the company's innovative approach to cancer treatment, particularly its lead candidate, could position it favorably in the market. The current valuation may present a buying opportunity for investors looking for undervalued stocks in the biotech sector. The company's promising pipeline and current stock valuation suggest significant potential for future performance and investor interest.

30 Jan

4

IO Biotech, Inc. (IOBT) provided a corporate update highlighting advancements in its clinical programs and strategic initiatives. The company is focused on developing innovative therapies for cancer treatment, with ongoing trials for its lead product candidates. IOBT also discussed its financial position and plans for future growth, emphasizing its commitment to addressing unmet medical needs in oncology. The update reflects the company's progress and strategic direction in the competitive biopharmaceutical landscape. Significant advancements in clinical programs and strategic initiatives could alter the company's trajectory and investor sentiment.

27 Jan

3

Piper Sandler has downgraded IO Biotech, Inc. (IOBT) as the company evaluates strategic alternatives. This decision reflects concerns about the company's current direction and potential future performance amidst ongoing assessments. The downgrade indicates a moderately noticeable influence on IO Biotech's market sentiment and operational outlook.

22 Jan

3

IO Biotech, Inc. (IOBT) has been identified as one of the most active stocks in the market, reflecting heightened trading activity and investor interest. The company's recent developments and market movements have contributed to its increased visibility among traders and analysts. This surge in activity may indicate potential shifts in investor sentiment or strategic developments within the company. Increased trading activity suggests a moderately noticeable influence on market sentiment and potential financial performance.

21 Jan

4

IO Biotech, Inc. (IOBT) has announced that it is exploring strategic alternatives to enhance shareholder value. This decision comes as the company seeks to evaluate various options, which may include partnerships, mergers, or other financial strategies. The exploration of these alternatives reflects IOBT's commitment to optimizing its operations and positioning in the biotechnology sector. Exploring strategic alternatives can lead to significant changes in the company's direction and market positioning.

20 Jan

4

IO Biotech, Inc. is considering a sale as it evaluates its strategic options amidst the ongoing performance of Moderna's cancer vaccine. The company is exploring potential partnerships or acquisition opportunities to enhance its market position and financial stability. Considering a sale indicates significant strategic shifts that could impact IO Biotech's future and market performance.

15 Dec

4

IO Biotech, Inc. announced the publication of five-year clinical outcomes from its Phase 1/2 trial in Nature Communications, highlighting the long-term efficacy and safety of its lead immunotherapy candidate. The study demonstrated promising results, indicating potential benefits for patients with cancer. This publication is expected to enhance the company's credibility and support future clinical development efforts. The publication of long-term clinical outcomes is likely to significantly impact investor sentiment and the company's strategic direction in immunotherapy.

26 Nov

3

IO Biotech, Inc. (IOBT) announced its participation in several investor conferences scheduled for December. The company aims to engage with investors and provide updates on its clinical programs and business strategy. These conferences present an opportunity for IOBT to enhance visibility and attract potential investors. Participation in investor conferences can moderately influence market sentiment and investor interest.

19 Nov

4

IO Biotech, Inc. (IOBT) has been upgraded to a 'Buy' rating by analysts due to positive developments in its clinical trials and promising data related to its cancer treatment therapies. The upgrade reflects confidence in the company's potential for growth and improved market performance, driven by advancements in its product pipeline and strategic initiatives aimed at enhancing shareholder value. The upgrade indicates significant potential for improved market performance and investor sentiment due to advancements in clinical trials and product development.

14 Nov

4

IO Biotech, Inc. (IOBT) reported its financial results for the third quarter of 2025, highlighting key business developments and financial metrics. The company continues to advance its pipeline and strategic initiatives, aiming to enhance its market position and shareholder value. Specific figures regarding revenue, expenses, and future outlook were provided, indicating ongoing efforts to drive growth and innovation in the biotech sector. The financial results and business highlights suggest significant strategic moves that could alter the company's trajectory and investor sentiment.

7 Nov

4

IO Biotech, Inc. presented pre-clinical data at the 2025 Annual Meeting of the Society for Immunotherapy of Cancer (SITC), showcasing the potential of additional therapeutic cancer vaccine candidates. The data highlights advancements in the company's research and development efforts in the field of immunotherapy, indicating promising avenues for future cancer treatments. The presentation of pre-clinical data on new therapeutic candidates could significantly influence IO Biotech's strategic positioning and investor sentiment in the competitive cancer treatment market.

20 Oct

4

IO Biotech, Inc. presented Phase 3 results for Cylembio® in combination with KEYTRUDA® (pembrolizumab) for first-line advanced melanoma at ESMO 2025. The study demonstrated promising efficacy and safety profiles, potentially positioning Cylembio® as a significant treatment option in this competitive market. The results are expected to influence future clinical strategies and market positioning for IO Biotech. The Phase 3 results could significantly impact IO Biotech's market position and investor sentiment regarding its product offerings.

30 Sep

4

IO Biotech, Inc. faces a setback as the FDA has opposed the submission of the Biologics License Application (BLA) for its Cylembio treatment, according to Morgan Stanley. This opposition raises concerns about the future of the drug's approval and the company's prospects in the competitive biotech landscape. The FDA's opposition to the BLA submission is a significant regulatory hurdle that could alter the company's trajectory and investor sentiment.

29 Sep

4

IO Biotech, Inc. provided an update following its Pre-BLA meeting with the FDA regarding its lead product candidate, IO102. The company received feedback on its planned Biologics License Application (BLA) submission and is preparing to address the FDA's comments. IO Biotech is focused on advancing its clinical development and regulatory strategy to bring IO102 to market for treating cancer patients. The company remains optimistic about the potential for its product to meet unmet medical needs. The feedback from the FDA on the BLA submission is a significant regulatory milestone that could greatly influence the company's future trajectory.

23 Sep

4

IO Biotech, Inc. announced that a late-breaking abstract on its treatment for advanced melanoma has been selected for oral presentation at the ESMO Congress 2025. This recognition highlights the significance of their research in the field of oncology and may enhance the company's visibility and credibility within the medical community. The selection for oral presentation at a major congress indicates significant interest and potential impact on IO Biotech's strategic positioning and investor sentiment.

4 Sep

3

IO Biotech, Inc. (IOBT) announced its participation in several upcoming investor conferences, including the H.C. Wainwright 25th Annual Global Investment Conference and the Cantor Fitzgerald Global Healthcare Conference. The company aims to engage with investors and provide updates on its clinical programs and business strategy. These conferences are opportunities for IOBT to enhance visibility and attract potential investors. Participation in investor conferences can moderately influence investor sentiment and visibility but is not expected to significantly alter the company's trajectory.

3 Sep

4

IO Biotech, Inc. (IOBT) has been upgraded to a 'Buy' rating by analysts, reflecting positive sentiment regarding its future performance. The upgrade is attributed to the company's promising pipeline and recent advancements in its clinical trials, which are expected to enhance its market position. Investors are encouraged to consider the potential for growth as IOBT continues to develop its innovative therapies. The upgrade indicates significant potential for improved market performance due to advancements in clinical trials and product development.

26 Aug

3

H.C. Wainwright has reiterated a Buy rating on IO Biotech, Inc. (IOBT) and maintained its price target at $14, indicating confidence in the company's future performance and potential growth in the market. The reaffirmation of the Buy rating and price target suggests a moderately positive outlook for IO Biotech's market position.

14 Aug

3

IO Biotech, Inc. (IOBT) reported its financial results for the second quarter of 2025, highlighting key business developments and financial metrics. The company continues to advance its pipeline and strategic initiatives, aiming to enhance its market position and drive future growth. Specific figures regarding revenue, expenses, and other financial indicators were disclosed, reflecting the company's ongoing efforts in the biotechnology sector. The financial results and business highlights indicate moderate influence on IO Biotech's performance and market positioning.

11 Aug

3

IO Biotech, Inc. plans to pursue approval for its cancer vaccine despite missing key endpoints in a Phase III clinical trial. The company aims to address the trial's shortcomings and believes the vaccine still holds potential for treating cancer. IO Biotech is committed to advancing its development efforts and engaging with regulatory authorities to explore the next steps for the vaccine's approval process. The Phase III trial miss may limit immediate investor confidence, but the company's commitment to pursue approval indicates potential for future developments.

3

IO Biotech, Inc. (IOBT) has been identified as one of the most active stocks in the market, reflecting heightened trading activity and investor interest. The company's recent developments and market movements have contributed to its visibility among investors, indicating potential shifts in market sentiment and engagement with its stock. This increased activity may be linked to broader trends in the biotech sector or specific company announcements that have captured attention. Increased trading activity suggests a moderate influence on market sentiment and potential interest in the company's future prospects.

3

IO Biotech, Inc. is optimistic about the future of its skin cancer vaccine despite a recent setback in clinical trials. The company believes it has identified a path forward to address the challenges faced in the study, which may involve adjustments to the vaccine's formulation or trial design. IO Biotech remains committed to advancing its innovative therapies aimed at treating cancer, and the management is focused on leveraging insights gained from the trial to enhance the vaccine's efficacy and patient outcomes. The setback in clinical trials presents challenges, but the company's identified path forward indicates potential for moderate influence on future performance.

3

IO Biotech, Inc. announced clinical improvements in progression-free survival in its pivotal Phase 3 trial of Cylembio® combined with KEYTRUDA® (Pembrolizumab) for first-line advanced melanoma treatment. However, the results narrowly missed statistical significance, raising questions about the therapy's efficacy. The trial results indicate potential benefits but lack statistical significance, which may limit immediate financial impact and market perception.

10 Aug

4

IO Biotech, Inc. will announce the topline results of its pivotal Phase 3 trial for Cylembio® in combination with KEYTRUDA® (pembrolizumab) as a first-line treatment for patients with advanced melanoma. This announcement is anticipated to provide critical data regarding the efficacy and safety of the treatment regimen. The results of this pivotal trial could significantly influence IO Biotech's market position and investor sentiment.

16 Jul

3

Private equity firms control 52% of IO Biotech, Inc. (NASDAQ:IOBT), significantly influencing management decisions. Their ownership was rewarded with a US$16m increase in market cap last week. Institutional investors also hold a notable stake, while insiders own less than 1%. The general public holds 33%, allowing some influence over company policies. Despite the significant ownership by private equity, insiders have been buying shares recently, indicating potential confidence in the company's future. The influence of private equity firms and institutional investors may moderately affect IO Biotech's financial performance and strategic direction.

28 May

3

IO Biotech, Inc. (IOBT) has recently shown a golden cross signal, indicating a potential bullish trend in its stock performance. This technical analysis pattern occurs when a short-term moving average crosses above a long-term moving average, suggesting increased investor interest and possible upward momentum. Analysts are evaluating whether this signal presents a buying opportunity for investors looking to capitalize on potential gains in the company's stock. The golden cross signal may influence market sentiment and short-term trading but does not guarantee a fundamental shift in the company's long-term trajectory.

20 May

4

IO Biotech (Nasdaq: IOBT) announced participation in the TD Cowen 6th Annual Oncology Summit on May 27, 2025, featuring a fireside chat with CEO Mai-Britt Zocca, CFO Amy Sullivan, and CMO Qasim Ahmad. Additionally, Dr. Zocca will present at the Jefferies Global Healthcare Conference from June 3-5, 2025, in New York. The company is advancing its investigational cancer vaccine Cylembio® through pivotal trials in combination with Merck's KEYTRUDA®. Participation in major healthcare conferences and ongoing pivotal trials for Cylembio® are likely to significantly impact IO Biotech's future performance and investor sentiment.

15 May

3

H.C. Wainwright raised the price target for IO Biotech (IOBT) from $12 to $14 while maintaining a Buy rating after the Q1 report, citing lower than expected operating expenses. The analyst noted that IO's Phase 3 advanced melanoma data is on track for Q3. The increase in price target and positive outlook on the Phase 3 data indicate a moderately noticeable influence on IO Biotech's market performance.

14 May

3

IO Biotech, Inc. (IOBT) reported its financial results for the first quarter of 2025, highlighting key business developments and financial metrics. The company continues to advance its pipeline and strategic initiatives, aiming to enhance its market position and drive growth. Specific figures regarding revenue, expenses, and future outlook were provided, indicating the company's ongoing commitment to innovation and development in the biotech sector. The financial results and business highlights suggest a moderately noticeable influence on IO Biotech's future performance and market positioning.

26 Apr

4

IO Biotech showcased its scientific leadership at the AACR Annual Meeting 2025, where co-founder Dr. Mads Hald Andersen presented on advancements in cancer vaccines, particularly the dual mechanism of action of IO102-IO103. This immune-modulatory vaccine targets tumor cells and immune suppressive cells, potentially reshaping the tumor microenvironment. IO Biotech's lead candidate has received Breakthrough Therapy Designation for advanced melanoma treatment, highlighting its innovative approach to cancer immunotherapy. The presentation of significant advancements in cancer vaccine research and the Breakthrough Therapy Designation for IO102-IO103 are likely to significantly impact IO Biotech's future performance and market perception.

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