Heron Therapeutics, Inc.

HRTX Healthcare Biotechnology

Heron Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $154.9 million, up 7.36% from fiscal 2024. In the quarter to June 2026, revenue grew 1.25%, EPS fell 93.6%, free cash flow grew 78.8% and total debt fell 18.5%, each against the same quarter a year earlier. Revenue growth for three consecutive years.

0.36 0.02 −5.26%
Market cap
$71.5M
P/E
0.0×
Fwd P/E
−6.6×
Dividend yield
—
F-score
4/9
Altman Z
−8.84
Beneish M
−2.40
Dividend safety
n/a

Insider Decisions trades per month

Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 1.25%

Capital & Financial Ratios $m

Market Cap 71.48
Revenue 151.18
Net Income (34.05)
Free Cash Flow (12.09)
Net Debt 99.99
Current Ratio 2.49 (at or above 1.5: strong)
Debt/Equity 20.65 (above 2: weak)
P/E ratio 0.00
Fwd P/E (6.58) (negative: loss-making)
P/S ratio 0.45
P/B ratio 11.70 (above 6: high)
Past 5Y EPS Growth —
This Y EPS Growth (8.33%) (below 0%: weak)
Next Y EPS Growth 15.38% (at or above 15%: strong)
Next Y revenue growth (4.33%) (below 0%: weak)
Next 5Y EPS Growth 22.90% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 1.79%
10-year low 10-year high
P/B against its own 10 years 66.92%
10-year low 10-year high
EV/Sales against its own 10 years 1.79%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 80 59 47 43
Receivables 60 79 90 90
Inventory 42 53 93 91
Other — — — —
189 209 238 230
2023 2024 2025 Q'26
Payables 3 12 9 12
ST’ Debt — — — —
Other — — — —
80 91 96 92

Compound Annual Growth %

10y 5y 3y
Sales — 11.81% 12.89%
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (19.01%) (42.92%) 1.84%

Revenue $m

Mar Jun Sep Dec Year
’26 35 38 — — —
’25 39 37 38 41 155
’24 35 36 33 41 144
’23 30 32 31 34 127
’22 23 28 27 30 108
’21 20 22 23 21 86
’20 25 23 20 21 89
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (2) (2) — — —
’25 (9) (11) 1 (9) (28)
’24 (10) (5) 3 (12) (23)
’23 (25) (27) (9) 2 (59)
’22 (44) (28) (37) (38) (147)
’21 (42) (63) (53) (45) (203)
’20 (33) (57) (42) (53) (185)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (2) (2) — — —
’25 (9) (11) 1 (9) (28)
’24 (10) (5) 3 (12) (24)
’23 (25) (27) (10) 2 (60)
’22 (45) (29) (37) (38) (149)
’21 (43) (63) (55) (46) (206)
’20 (36) (58) (43) (55) (192)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.04) (0.03) — — —
’25 0.01 (0.02) (0.10) (0.02) (0.12)
’24 (0.02) (0.06) (0.03) 0.02 (0.09)
’23 (0.27) (0.35) (0.17) (0.07) (0.80)
’22 (0.63) (0.55) (0.38) (0.17) (1.67)
’21 (0.58) (0.62) (0.51) (0.54) (2.24)
’20 (0.57) (0.61) (0.64) (0.68) (2.50)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

3
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 12.30 12.21 17.85 15.68 9.60 8.23 2.19 0.50 1.04 1.00

Analyst estimates 2026–2028

Powerpack
High 28.10 19.55 42.90 28.70 24.76 21.64 10.40 3.41 3.93 2.68
People
People Employees 139 145 198 231 223 302 203 126 122 128
Revenue/emp, $m 0.01 0.21 0.39 0.63 0.40 0.29 0.53 1.01 1.18 1.21
Income, $m
Income, $m Revenue 1 31 77 146 89 86 108 127 144 155
Gross margin, % 97.26 85.09 64.49 57.79 59.17 46.70 49.04 48.75 73.21 73.31
EBT (173) (197) (179) (205) (227) (221) (182) (111) (14) (20)
EBT margin, % (13,537.37) (641.87) (230.84) (140.27) (256.41) (255.58) (169.05) (87.02) (9.41) (13.04)
Net income (173) (197) (179) (205) (227) (221) (182) (111) (14) (20)
Depreciation 2 2 (1) (1) 4 4 2 1 1 2
Per share, $
Per share, $ Revenue 0.03 0.57 1.06 1.78 0.98 0.88 0.99 0.92 0.95 0.93
Earnings (4.56) (3.65) (2.44) (2.50) (2.50) (2.24) (1.67) (0.80) (0.09) (0.12)
Cash flow (3.54) (3.15) (2.62) (1.52) (2.04) (2.07) (1.35) (0.43) (0.15) (0.17)
Capex (0.08) (0.05) (0.12) (0.09) (0.08) (0.03) (0.01) (0.01) (0.01) 0.00
Free cash flow (3.62) (3.20) (2.75) (1.61) (2.11) (2.10) (1.36) (0.44) (0.16) (0.17)
Book value (0.56) 2.43 5.06 4.94 2.61 0.79 0.12 (0.25) (0.22) 0.09
Shares, m 38 54 73 82 91 98 109 138 152 167
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S 0.00 32.49 24.51 13.17 21.68 10.41 2.46 2.06 1.62 1.40
P/B 0.00 7.62 5.13 4.76 8.13 11.59 19.49 0.00 0.00 16.32
EV/Sales 0.00 27.70 20.54 10.57 19.49 10.31 3.06 2.79 2.42 2.01
EV/FCF (3.69) (4.93) (7.92) (11.71) (9.02) (4.32) (2.22) (5.88) (14.26) (11.17)
Cash, $m
Cash, $m Operating cash flow (134) (170) (192) (125) (185) (203) (147) (59) (23) (28)
Capex (3) (2) (9) (7) (7) (3) (2) (2) (2) 0
Free cash flow (137) (173) (201) (132) (192) (206) (149) (60) (24) (28)
Balance, $m
Balance, $m Working capital 23 125 355 382 212 183 123 109 118 142
Total debt 50 29 5 12 15 149 149 174 175 141
Net debt (1) (172) (332) (379) (194) (8) 64 93 115 94
Shareholders’ equity (21) 131 370 404 236 78 14 (34) (34) 14
Returns, %
Returns, % ROA (168.65) (130.88) (51.35) (42.00) (52.47) (66.95) (65.40) (46.70) (5.96) (8.26)
ROIC 0.00 0.00 (304.22) (524.53) (335.05) (197.10) (139.94) (116.44) (8.81) (1.46)
ROE (357.52) (359.44) (71.35) (52.91) (70.99) (140.53) (399.43) 1,083.86 40.16 198.30
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Heron Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
NTRB Nutriband Inc. $76.2M — (loss-making) 4.6× −29.72% (below 0%: shrinking) n/m +55.46% (above 0%: growing) 41.58% (203.57%) Compare
CRDF Cardiff Oncology, Inc. $75.5M — (loss-making) — (loss-making) −14.05% (below 0%: shrinking) n/m −41.36% (below 0%: shrinking) 100.00% (9,245.19%) Compare
ACRV Acrivon Therapeutics, Inc. $75.4M — (loss-making) — — n/m +12.59% (above 0%: growing) 0.00% 0.00% Compare
OKYO OKYO Pharma Limited Sponsored ADR $75.1M — (loss-making) — — n/m +37.39% (above 0%: growing) 0.00% — Compare
PDSB PDS Biotechnology Corporation $72.8M — (loss-making) — — n/m +69.32% (above 0%: growing) 0.00% 0.00% Compare
HRTX Heron Therapeutics, Inc. $71.5M — (loss-making) — (loss-making) +1.25% (above 0%: growing) n/m +78.75% (above 0%: growing) 69.28% (5.43%)
MNOV MediciNova, Inc. $71.4M — (loss-making) — (loss-making) +240.56% (above 0%: growing) n/m +16.75% (above 0%: growing) 69.33% (554.36%) Compare
CGTX Cognition Therapeutics, Inc. $69.7M — (loss-making) — — n/m +45.35% (above 0%: growing) 0.00% 0.00% Compare
MAIA MAIA Biotechnology, Inc. $69.2M — (loss-making) — — n/m −63.23% (below 0%: shrinking) — 0.00% Compare
Median of peers $73.9M — — −14.05% — +27.07% 0.00% 0.00%

All 614 Biotechnology stocks →

Heron Therapeutics, Inc. (HRTX) key facts

  • Strength: Heron Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $154.9 million, up 7.36% from fiscal 2024.
  • Heron Therapeutics, Inc. (HRTX) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, HRTX traded at $0.36, a market capitalization of $71.5 million.
  • Return on equity was 198.3% and debt-to-equity 20.65.
  • Its Piotroski F-score is 4 out of 9 and its Altman Z-score is −8.84 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Heron Therapeutics, Inc. (HRTX) Latest News

stockrow.com/HRTX · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com