HCW Biologics Inc. HCWB

1.93 (0.06) (3.02%) as of 25 Sep
Market cap
$4.2M
P/E
0.0×
Insider Buys alert about insiders buying in the last 12 month

Insider Decisions

Total buys 0.53
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — 3 — 3 — —
Sell — — — — — — — — — — — —
Insider Ownership 0.00%

Capital & Financial Ratios

Market Cap 4.18
Revenue 6.72
Net Income (5.58)
Free Cash Flow (12.14)
Net Debt 5.82
Current Ratio 0.06
Debt/Equity 0.88
P/E ratio 0.00
P/S ratio 0.38
P/B ratio 0.35
Past 5Y EPS Growth (29.55%)
This Y EPS Growth 95.48%
Next Y EPS Growth 8.33%
Next 5Y EPS Growth 67.95%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 4 5 2 1
Receivables 2 1 0 0
Inventory — — — —
Other 0 0 0 0
6 6 2 1
2023 2024 2025 Q'26
Payables 6 22 13 11
ST’ Debt — 6 7 7
Other — — — —
9 30 21 19
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — (79.95%)
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% (58.04%)

Revenue

Mar Jun Sep Dec Year
’26 7 0 — — —
’25 0 0 0 0 0
’24 1 1 0 0 3
’23 0 1 1 1 3
’22 3 0 2 1 7
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (2) (4) — — —
’25 (4) (3) (3) (3) (13)
’24 (4) (5) (3) (3) (14)
’23 (4) (9) (6) (4) (23)
’22 (2) (3) (2) (4) (10)
’21 (1) (1) (5) (3) (11)
’20 (2) (4) (3) (4) (10)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (2) (4) — — —
’25 (4) (3) (3) (3) (13)
’24 (4) (5) (3) (3) (14)
’23 (4) (11) (6) (8) (29)
’22 (2) (3) (12) (4) (21)
’21 (2) (1) (5) (3) (11)
’20 (2) (4) (3) (4) (11)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 2.22 (11.58) — — —
’25 (11.81) (40.73) (12.12) (6.12) (63.77)
’24 (1.20) (95.98) (23.99) (19.20) (184.76)
’23 (33.59) (28.79) (33.59) (71.99) (167.97)
’22 (14.40) (23.99) (26.21) (35.99) (100.78)
’21 (141.00) (158.37) (33.59) 143.91 (165.57)
’20 (0.07) (141.10) (137.02) — (293.79)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
— — — — — 554.40 422.40 218.40 66.24 5.72

Analyst estimates 2026–2028

Powerpack
Low Price
— — — — — 1,866.00 796.80 556.80 604.80 247.20
High Price
— — — — — 44 44 45 36 35
Employees
— — — — 0 0 0 0 0 0
Revenue/Emp
— — — — 4 — 7 3 3 0
Revenue
— — — 0.00% 100.00% 0.00% 38.48% 19.72% 37.38% 19.93%
Gross Margin
— — — (7) (6) (13) (15) (25) (30) (8)
EBT
— — — 0.00% (141.52%) 0.00% (221.67%) (879.52%) (1,169.70%) (14,685.79%)
EBT Margin
— 0 — (7) (6) (13) (15) (25) (30) (8)
Net Income
— — — 0 1 1 1 1 1 1
Depreciation
— — — 0.00 208.11 0.00 45.02 18.98 15.87 0.16
Revenue/Sh
— — — (0.21) (293.79) (165.57) (100.78) (167.97) (184.76) (63.77)
Earnings/Sh
— — — (0.18) (529.51) (140.35) (69.57) (150.39) (87.99) (38.29)
Cash Flow/Sh
— — — 0.00 (9.48) (0.60) (68.82) (41.43) (1.62) 0.00
Capex/Sh
— — — (0.18) (538.98) (140.96) (138.39) (191.83) (89.60) (38.29)
Free CF/Sh
— — — 0.25 (848.65) 654.64 250.69 89.92 (41.87) 7.91
Book Value/Sh
— — — 37 0 0 0 0 0 0
Shares
— — — — 0.00 — 0.00 0.00 0.00 0.00
PE Ratio
— — — — 0.00 — 10.45 15.17 6.74 37.55
PS Ratio
— — — — 0.00 — 1.88 3.20 0.00 0.74
PB Ratio
— — — — 0.00 — 6.63 16.18 10.26 133.75
EV/Sales
— — — — (2.90) — (2.16) (1.60) (1.82) (0.53)
EV/FCF
— — — (7) (10) (11) (10) (23) (14) (13)
Op' Cash Flow
— — — (1) 0 0 (10) (6) 0 —
Capex
— — — (7) (11) (11) (21) (29) (14) (13)
FCF
— — — 7 11 38 31 (2) (24) (19)
Working Cap'
— — — — 1 — 6 6 14 7
Total Debt
— — — (7) (8) (37) (26) 3 9 5
Net Debt
— — — 9 (17) 51 37 13 (7) 3
Sh' Equity
— — — (154.63%) (55.56%) (37.33%) (29.71%) (66.37%) (102.21%) (81.45%)
ROA
— — — 0.00% 0.00% (57.70%) (80.03%) (99.40%) (819.04%) (107.94%)
ROIC
— — — 58.97% 53.60% (74.62%) (33.63%) (98.23%) (897.37%) 1,113.43%
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

HCW Biologics Inc. peers in Biotechnology

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HCW Biologics Inc. (HCWB) key facts

  • HCW Biologics Inc. (HCWB) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of September 25, 2026, HCWB traded at $1.93, a market capitalization of $4.2 million.
  • Return on equity was 1,113.4% and debt-to-equity 0.88.

Source: company filings (standardised) and stockrow calculations.

HCW Biologics Inc. (HCWB) Latest News

News by impact score

Fine-tune

24 Sep

3

HCW Biologics Inc. priced a $1.5 million private placement with an existing stockholder. The offering covers 903,614 units; each includes a pre-funded warrant to buy one share of common stock and the right to receive one common warrant, subject to stockholder approval. The combined price per Unit is $1.6599. Pre-funded warrants have an exercise price of $0.0001, exercisable immediately and will not expire until exercised in full. Common warrants have an exercise price of $1.66 and will expire 5.5 years after issuance; issuance of these warrants requires stockholder approval under Nasdaq Rule 5635(d). If approved, the company will issue the common warrants to the investor. Maxim Group LLC is the placement agent. Proceeds will fund HCW9302, IND-enabling studies for HCW11-018b, HCW11-040, and general corporate purposes; Form S-1 registration will be filed within 15 trading days of closing. Ownership cap at 9.99% of outstanding common stock. The financing provides a modest capital raise with potential dilution upon warrant exercise, likely affecting near-term liquidity and investor sentiment but not altering core strategy.

8 Sep

3

HCW Biologics signed an exclusive distribution agreement with Akron Biotech to commercialize HCW11-006 as a reagent supporting production of highly functional human CAR-T cells. Distribution agreement broadens commercial access for HCW11-006 in CAR-T manufacturing.

2 Sep

3

HCW Biologics strengthens U.S. patent estate for lead clinical-stage immunotherapeutic HCW9302 as alopecia areata treatment. Patent strengthening for core candidate HCW9302 improves IP protection and supports future market positioning.

25 Aug

4

HCW Biologics develops TGF-β Trap and IL-15 fusion protein as novel approach to boost immunotherapy against diseased cells. Novel fusion protein advances company's core immunotherapy pipeline with potential to shift competitive position.

4

HCW Biologics Inc. (HCWB) announced the showcasing of its novel second-generation immune checkpoint inhibitor, which is identified as a potential entry point into a multi-billion dollar market. This development highlights the company's innovative approach in the competitive landscape of immunotherapy, aiming to enhance treatment options for patients and capture significant market share. The introduction of a novel immune checkpoint inhibitor could significantly impact HCWB's market positioning and investor sentiment.

3

HCW Biologics Inc. (HCWB) has been identified as one of the most active stocks in the market, reflecting heightened trading activity and investor interest. The company's recent developments and market performance have contributed to its visibility among investors, indicating potential shifts in market dynamics. Increased trading activity suggests a moderately noticeable influence on investor sentiment and market positioning.

23 Jul

3

HCW Biologics reached milestones in its proprietary tetravalent second-generation T-cell engager program and remains on track to initiate clinical trials in the first half of 2027. Milestone achievement advances the T-cell engager program toward clinical development but with trials not starting until 2027 the near-term market impact remains limited.

16 Jun

4

HCW Biologics announces positive preliminary human data from its Phase 1 trial of HCW9302, an IL-2 fusion immunotherapeutic, as monotherapy in alopecia areata. Positive Phase 1 data readout for HCW9302 advances pipeline and lifts prospects for alopecia areata treatment.

27 May

3

HCW Biologics exercised option to regain full rights for two commercial-ready reagents from Wugen. Regaining rights to commercial reagents moderately strengthens HCWB control over assets and future revenue potential.

14 May

4

HCW Biologics discovers that HCW11-040 prevents bronchopulmonary dysplasia (BPD) during IND-enabling studies. Preclinical success of HCW11-040 in preventing BPD advances pipeline toward clinical trials and enhances market prospects.

3

HCW Biologics Inc. (HCWB) reported first quarter 2026 business highlights and financial results. Quarterly business highlights and financial results affect key financial performance and investor sentiment.

27 Apr

4

HCW Biologics reveals mechanism of action for its T-Cell Engager Program and validates Tissue Factor as a target for solid tumor treatment. Major program update revealing mechanism of action and target validation advances HCWB's pipeline for solid tumors, boosting investor sentiment and competitive positioning.

31 Mar

3

HCW Biologics Inc. (HCWB) reported fourth quarter 2025 and full fiscal year 2025 business highlights and financial results. Quarterly and annual financial results disclosure impacts financial performance and investor sentiment.

17 Mar

4

HCW Biologics Inc. (HCWB) closes exclusive worldwide license for HCW11-006, a high-potential fusion immunotherapeutic. Closing an exclusive worldwide license for a high-potential fusion immunotherapeutic is a major strategic move enhancing HCWB's product pipeline and market position.

16 Mar

4

HCW Biologics announces positive research results for CAR-T cell therapy manufactured using its commercial-ready proprietary compound HCW9206, with findings published in Science Advances. Prestigious publication of positive CAR-T results using commercial-ready HCW9206 validates the platform's efficacy, likely enhancing investor sentiment and competitive positioning.

2 Mar

4

HCW Biologics Inc. (HCWB) regained compliance with all Nasdaq continued listing rules following a determination letter from Nasdaq. Regaining full Nasdaq compliance averts delisting risk and significantly enhances market stability and investor sentiment.

13 Feb

4

HCW Biologics Inc. and WY Biotech have successfully closed the first round of financing for their newly formed joint venture, Trimmune. This collaboration aims to advance the development of innovative therapies, leveraging the strengths of both companies to enhance their market position and product offerings. The formation of a joint venture and successful financing round is a significant strategic move that could enhance product development and market competitiveness.

19 Nov

3

HCW Biologics Inc. has entered into a $4.0 million warrant inducement priced at-the-market under Nasdaq rules. This move is aimed at attracting investors and enhancing the company's financial position. The warrants are expected to provide additional capital for HCW Biologics to support its ongoing operations and strategic initiatives. The warrant inducement is likely to provide moderate financial support, influencing the company's operations but not fundamentally altering its trajectory.

18 Nov

4

HCW Biologics Inc. has announced the initiation of a first-in-human clinical trial to evaluate HCW9302, a novel therapeutic candidate aimed at treating autoimmune diseases. This trial marks a significant step in the company's development pipeline, potentially addressing unmet medical needs in this area. The study will assess the safety and efficacy of HCW9302, with results expected to provide insights into its therapeutic potential. The initiation of a first-in-human clinical trial for HCW9302 could significantly impact HCW Biologics' future performance and market position in the autoimmune disease sector.

14 Nov

4

HCW Biologics Inc. reported its third quarter 2025 business highlights and financial results, showcasing advancements in its product pipeline and financial performance metrics. The company emphasized its commitment to developing innovative biologics and expanding its market presence. Key financial figures indicated growth in revenue and a reduction in operational costs, reflecting effective management strategies. HCW Biologics also outlined future plans for product development and potential collaborations aimed at enhancing its competitive position in the biotechnology sector. Significant advancements in product development and financial performance are likely to influence investor sentiment and the company's market trajectory.

10 Nov

4

HCW Biologics Inc. presented new data for its second-generation immune checkpoint inhibitor at the 40th Annual Meeting of the Society for Immunotherapy of Cancer. The findings highlight advancements in the treatment's efficacy and safety profile, positioning HCWB favorably in the competitive landscape of immunotherapy. The presentation of significant data on a second-generation immune checkpoint inhibitor is likely to influence investor sentiment and the company's market position.

7 Nov

4

HCW Biologics Inc. presented preclinical data for its TRBC-based T-cell engager program at the Society for Immunotherapy of Cancer’s 40th Annual Meeting. The data highlights the potential of this innovative approach in enhancing T-cell responses against cancer, showcasing promising results that could lead to further development and clinical applications. The presentation of preclinical data indicates significant advancements in product innovation that could enhance the company's competitive positioning in the immunotherapy market.

16 Oct

3

HCW Biologics Inc. (HCWB) will participate in the 2025 Maxim Growth Summit, showcasing its commitment to growth and innovation in the biotech sector. The event will provide a platform for HCWB to engage with investors and industry leaders, highlighting its strategic initiatives and future prospects. Participation in the summit may enhance investor engagement and market visibility, but its overall impact on the company's trajectory is expected to be limited.

3

HCW Biologics Inc. will present three scientific posters at the 40th Annual Meeting of the Society for Immunotherapy of Cancer. The presentations will showcase the company's advancements in immunotherapy research, highlighting their innovative approaches and findings in the field. This event is a significant opportunity for HCW Biologics to engage with industry experts and share their contributions to cancer treatment. Presenting at a major industry conference can enhance visibility and credibility, potentially influencing future collaborations and funding opportunities.

30 Sep

4

HCW Biologics Inc. (NASDAQ: HCWB) participated in a virtual investor segment titled 'What This Means,' focusing on its proprietary T-Cell Engager Program. The discussion highlighted the potential of the program in advancing cancer therapies and the company's strategic vision for future developments in immunotherapy. The focus on the proprietary T-Cell Engager Program indicates a significant strategic initiative that could enhance the company's competitive positioning in the immunotherapy market.

18 Sep

3

HCW Biologics Inc. congratulates Wugen on successfully completing its recent equity financing. As a shareholder, HCWB expresses optimism about Wugen's future prospects following this financial milestone, which is expected to enhance Wugen's operational capabilities and growth potential. Wugen's successful equity financing may positively influence HCWB's investment value and market sentiment.

16 Sep

4

HCW Biologics Inc. has designated one of its proprietary TRBC-Pembrolizumab-based immune checkpoint inhibitors as its primary immunotherapeutic for internal clinical development. This strategic move aims to enhance the company's focus on advancing its immunotherapy pipeline, potentially positioning it for significant growth in the competitive biopharmaceutical landscape. Designating a proprietary immunotherapeutic for internal development indicates a major strategic focus that could significantly impact future performance and investor sentiment.

9 Sep

4

HCW Biologics Inc. announced positive results from a non-human primate study for its proprietary second-generation T-cell engager program, indicating potential advancements in cancer treatment. The study demonstrated enhanced efficacy and safety profiles, supporting the company's ongoing development efforts in immunotherapy. These findings may pave the way for future clinical trials and product development. Positive study results could significantly impact HCW Biologics' product development and market positioning in the immunotherapy sector.

18 Aug

4

HCW Biologics Inc. reported its second quarter 2025 business highlights and financial results, showcasing advancements in its product pipeline and financial performance metrics. The company emphasized its commitment to innovation and strategic growth, highlighting key partnerships and ongoing clinical trials that are expected to enhance its market position. Financial results indicated a positive trajectory, with increased revenues and reduced operational costs, reflecting effective management and operational efficiencies. Significant advancements in product development and financial performance are likely to influence investor sentiment and the company's market trajectory.

2 Jul

3

HCW Biologics Inc. (NASDAQ:HCWB) experienced a 14% drop in stock value, impacting insiders who invested US$3.05m at an average price of US$22.83, now worth only US$500.2k. Despite this, insiders have recently purchased US$3.0m worth of shares, indicating a positive outlook. Founder Hing Wong made the largest purchase of US$2.4m at US$26.00 per share. Insiders own 40% of the company, suggesting alignment with shareholder interests. However, the company did not profit in the last year, raising caution. Eight warning signs have been identified for potential investors. Insider buying suggests confidence, but lack of profitability and warning signs indicate caution.

stockrow.com/HCWB · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com