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Target Price Range
Recommendation Rating
| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | 2028 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ‡‡‡‡ | ‡‡‡‡ | ‡‡‡‡ | ‡‡‡‡ | ‡‡‡‡ | ‡‡‡‡‡ | 2.12 | 2.20 | 3.49 | 4.70 | — | — | — |
Low Price
|
| ‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡ | ‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | 23.10 | 5.01 | 12.22 | 14.43 | — | — | — |
High Price
|
| — | — | — | — | — | ‡‡‡‡ | 48 | 57 | 74 | 106 | — | — | — |
Employees
|
| — | — | — | — | — | ‡‡‡ | 0.00 | 0.00 | 0.00 | 0.00 | — | — | — |
Revenue/Emp
|
| — | — | — | — | — | — | — | — | — | — | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | Revenue |
| — | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | 0.00% | — | — | — | — | — | — |
Gross Margin
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (56.80) | (95.73) | (108.68) | (183.79) | — | — | — |
EBT
|
| ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | 0.00% | 0.00% | 0.00% | 0.00% | ‡‡‡ | ‡‡‡ | ‡‡‡ |
EBT Margin
|
| ‡‡‡‡‡ | ‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (56.80) | (95.73) | (108.68) | (183.79) | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ |
Net Income
|
| — | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | 3.18 | 3.26 | 0.53 | (1.82) | — | — | — |
Depreciation
|
| ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | 0.00 | 0.00 | 0.00 | 0.00 | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ |
Revenue/Sh
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (1.84) | (2.44) | (1.54) | (2.06) | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ |
Earnings/Sh
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (1.62) | (1.64) | (1.12) | (1.47) | — | — | — |
Cash Flow/Sh
|
| ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | 0.00 | 0.00 | 0.00 | 0.00 | ‡‡‡ | ‡‡‡ | ‡‡‡ |
Capex/Sh
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (1.62) | (1.64) | (1.12) | (1.47) | — | — | — |
Free CF/Sh
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | 4.89 | 2.00 | 3.43 | 3.72 | — | — | — |
Book Value/Sh
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | 30.86 | 39.16 | 70.46 | 89.33 | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ |
Shares
|
| — | — | — | — | — | — | — | — | — | — | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | PE Ratio |
| — | — | — | — | — | — | — | — | — | — | ‡‡‡ | ‡‡‡ | ‡‡‡ | PS Ratio |
| — | — | — | — | — | — | — | — | — | — | ‡‡‡ | ‡‡‡ | ‡‡‡ | PB Ratio |
| — | — | — | — | — | — | — | — | — | — | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡ | EV/Sales |
| — | — | — | — | — | — | — | — | — | — | — | — | — | EV/FCF |
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (50.14) | (64.36) | (79.13) | (131.56) | ‡‡‡ | ‡‡‡ | ‡‡‡ |
Op' Cash Flow
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | — | — | — | — | — | — | ‡‡‡‡‡ | ‡‡‡‡‡ | — | Capex |
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (50.14) | (64.36) | (79.13) | (131.56) | — | — | — |
FCF
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | 128.16 | 71.63 | 242.77 | 352.62 | — | — | — |
Working Cap'
|
| — | ‡‡‡‡‡ | — | — | — | — | 0.05 | 14.13 | 21.85 | 40.58 | — | — | — |
Total Debt
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (142.09) | (85.57) | (251.89) | (371.01) | — | — | — |
Net Debt
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | 150.92 | 78.13 | 241.45 | 332.33 | — | — | — |
Sh' Equity
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (34.01%) | (65.01%) | (50.94%) | (49.52%) | — | — | — |
ROA
|
| ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡ | ‡‡‡‡‡ | (469.59%) | 0.00% | 0.00% | 0.00% | — | — | — |
ROIC
|
| ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | ‡‡‡‡‡ | (37.54%) | (83.59%) | (68.01%) | (64.06%) | — | — | — |
ROE
|
Analyst Commentary (Summary)
Definium Therapeutics, Inc. (DFTX) Latest News
20 Sep
Definium Therapeutics announced that its LSD-based pill cleared a second anxiety trial, marking another positive readout for its psychedelic program. The result signals momentum in LSD therapies for anxiety and could attract investor interest and potential partnerships, though substantial regulatory and competitive hurdles remain. Details on trial size, endpoints, and plans for larger pivotal studies were not provided. The news reinforces the psychedelics sector's growth narrative and places Definium among the more watched players, with potential near-term market impact but ongoing early-stage risk. Progress in a second anxiety trial signals meaningful advancement in LSD-based therapy and could broaden investor interest and potential partnerships.
19 Sep
Definium Therapeutics’ DT120 met primary and secondary endpoints in Phase III trial for anxiety treatment, showing strong efficacy and safety. Positive Phase III data for lead asset DT120 substantially raises odds of approval and commercial revenue for Definium Therapeutics.
15 Sep
Definium Therapeutics reports second Phase III success in anxiety disorder program. Second positive Phase III readout advances lead candidate toward approval and revenue potential.
Definium Therapeutics (DFTX) stock may trade at a premium despite Phase 3 DT120 results. Phase 3 DT120 results can substantially shift Definium Therapeutics valuation and investor outlook.
Definium Therapeutics readies regulatory submission for psychedelic after Phase III successes. Phase III completion and regulatory filing advance positions company for potential approval and market launch of lead asset.
Definium Therapeutics (DFTX) shares rose 5.7% after the second positive Phase 3 trial result for DT120 anxiety treatment. Positive Phase 3 DT120 data strengthens approval prospects and revenue potential for core pipeline asset.
Definium Therapeutics (DFTX) secured a Phase 3 win yet its shares remain undervalued. Phase 3 success opens major revenue paths and lifts long-term valuation outlook.
14 Sep
DFTX stock rose as much as 12% after the company reported unprecedented clinical data for its LSD-based anxiety drug. Strong positive data on core LSD anxiety drug produced immediate 12% stock surge and signals major trajectory shift for DFTX.
Definium Therapeutics Inc. (DFTX) stock surges 200% as Wall Street shifts focus to psychedelics biotech plays. 200% stock surge in psychedelics sector signals major momentum shift for company valuation and investor interest.
Positive psychedelics news drove Definium Therapeutics shares sharply higher, extending the stock's 190% gain for the year. Psychedelics-related developments triggered a sharp rally in Definium shares, pointing to material effects on market performance and investor sentiment.
DFTX shares rose 20% after Phase 3 anxiety trial met primary endpoint. Successful Phase 3 anxiety trial outcome positions Definium for potential approval and major revenue growth.
Definium Therapeutics succeeds with synthetic LSD, sending shares higher after a 190% gain this year. Synthetic LSD success and resulting share surge signal major strategic progress in a high-growth therapeutic area.
Definium Therapeutics reported positive topline results from its Phase 3 Panorama Study of DT120 ODT in generalized anxiety disorder. Positive Phase 3 results for lead candidate DT120 ODT mark a major regulatory milestone that can drive substantial valuation gains and partnership opportunities.
13 Sep
DFTX stock jumps overnight as investors brace for Phase 3 results from LSD-based anxiety drug. Phase 3 results for core LSD anxiety drug hold potential to reshape Definium Therapeutics trajectory and investor sentiment.
Definium Therapeutics, Inc. will discuss topline results from its Phase 3 Panorama Study in Generalized Anxiety Disorder on September 14, 2026. Phase 3 topline results in anxiety disorder can substantially shift company valuation, approval prospects, and market performance.
10 Sep
Definium Therapeutics will present topline data from Phase 3 Emerge and Voyage trials in major depressive disorder and generalized anxiety disorder at Psych Congress 2026. Phase 3 data presentations for lead psychiatric indications can substantially shift company valuation and investor sentiment.
8 Sep
Definium Therapeutics receives Breakthrough Therapy Designation for DT120 (lysergide) ODT in MDD after positive Phase 3 results. Breakthrough Therapy Designation plus positive Phase 3 data for DT120 accelerates regulatory path and commercial prospects in MDD.
14 Aug
DFTX voyage data renews focus on company valuation. Voyage data draws renewed attention to DFTX valuation without indicating major strategic shifts.
13 Aug
Successful Voyage Phase 3 data is transforming the investment case for Definium Therapeutics (DFTX). Successful Phase 3 trial results position Definium Therapeutics for major regulatory and market advances.
Definium Therapeutics (DFTX) met its Phase 3 endpoints for DT120 ODT in generalized anxiety disorder. Phase 3 success for DT120 ODT advances the candidate toward approval and revenue generation.
Definium Therapeutics' DT120 data boosts confidence in future trials, according to RBC Capital Markets. RBC Capital Markets' positive view of DT120 data signals strengthened prospects for Definium Therapeutics' trials and company trajectory.
Definium Therapeutics’ DT120 met Phase III study goals in generalized anxiety disorder, advancing the candidate toward potential regulatory approval and commercialization. Positive Phase III results for lead asset DT120 represent a major clinical milestone that can materially shift company trajectory and investor sentiment.
12 Aug
Definium Therapeutics shares surged after positive Phase 3 anxiety trial results. Positive Phase 3 anxiety trial results drive major regulatory and revenue upside for Definium Therapeutics.
DFTX shares rose after positive trial results for its psychedelic drug DT120 in anxiety treatment, with retail noting potential market disruption. Positive DT120 anxiety trial results strengthen DFTX drug pipeline and shift market positioning.
Definium Therapeutics achieves another success with its LSD-based drug, driving share prices higher. Drug development win directly strengthens company trajectory and stock performance.
Definium Therapeutics reports another success with its LSD-based drug, resulting in a sharp rise in DFTX stock price. Positive LSD-based drug results drive major stock gains and strengthen Definium's long-term trajectory.
Definium Therapeutics reported positive topline results from its Phase 3 Voyage study of DT120 ODT for generalized anxiety disorder. Positive Phase 3 results for DT120 ODT in generalized anxiety disorder mark a major milestone toward potential approval and commercial launch.
Definium Therapeutics reports additional positive clinical data for its LSD pill. Further positive data on LSD pill strengthens pipeline and market prospects.
11 Aug
DFTX shares head for worst day in nine months as investors await anxiety trial data. Anxiety trial data can materially alter Definium Therapeutics trajectory and investor sentiment.
7 Aug
Definium Therapeutics Inc reported record Phase III MDD results in its Q2 2026 earnings call, highlighting key clinical and financial milestones. Record Phase III MDD success signals major clinical progress with strong potential to shift company trajectory and investor outlook.
Definium Therapeutics (DFTX), a clinical-stage biotech chasing therapies for metabolic and endocrine disorders, embodies the biotech rollercoaster: explosive highs of $86 in 2021 fueled by pandemic hype and funding frenzies, crashing to pennies amid trial setbacks and dilution, with shares now trading at depressed levels despite analyst targets implying 14% to a staggering 290% upside. This decade-long saga mirrors sector booms and busts, from 58x share dilution since 2016 to ballooning losses—net income plunging 173% in peak years—while book value and cash swing wildly, underscoring R&D ambition clashing with execution hurdles.
Pre-revenue through 2024, DFTX burns cash relentlessly ($79M operating outflow last year), headcount doubled to 74, yet insiders—led by the CEO—dumped over $2.5M in shares across 2025 clusters with zero buys, flashing caution amid rising debt and negative ROE/ROA. Projections tease a 2025 revenue debut at $32M (flatlining after), still mired in losses but betting on commercialization like GLP-1 winners, with EV/Sales at 38x signaling premium growth hopes.
In a world of binary biotech bets, DFTX’s story echoes CAR-T and mRNA frenzies—peaks precede troughs—but near-term catalysts like Phase 3 data could ignite that 78% mean target upside, or falter into another 90% wipeout. With 12-18 months’ runway and mounting pressures, is this dilution-weary name poised for revival or rerun? Dive deeper for the full verdict.